Discovery and Mechanistic Study of a Totally Organic C(aryl)–C(alkyl)Oxygen Insertion Reaction

2019 ◽  
Vol 84 (21) ◽  
pp. 14349-14353 ◽  
Author(s):  
Muhammad Kazim ◽  
Hayden Foy ◽  
Maxime A. Siegler ◽  
Travis Dudding ◽  
Thomas Lectka
Keyword(s):  
Insertion Reaction ◽  
Mechanistic Study ◽  
Organic C ◽  
Oxygen Insertion

Mn-catalyzed radical initiated domino transformation of alkynylated cyclohexadienones with TMSN3 and O2 to bicyclic azido alcohols

2020 ◽  
Vol 56 (23) ◽  
pp. 3453-3456 ◽  
Author(s):  
Pranesh Pal ◽  
Prathama S. Mainkar ◽  
Kiranmai Nayani ◽  
Srivari Chandrasekhar
Keyword(s):  
Radical Addition ◽  
Insertion Reaction ◽  
Mild Conditions ◽  
Oxygen Insertion

An efficient cascade radical addition/cyclization/oxygen insertion reaction of alkyne-tethered cyclohexadienones with TMSN3 was carried out under mild conditions to generate bicyclic azido alcohol scaffolds.

Oxygen insertion into boroles as a route to 1,2-oxaborines

2016 ◽  
Vol 52 (40) ◽  
pp. 6658-6661 ◽  
Author(s):  
Sam Yruegas ◽  
Dayna C. Patterson ◽  
Caleb D. Martin
Keyword(s):  
Insertion Reaction ◽  
Oxygen Insertion

The synthesis of 1,2-oxaborines is accomplishedviathe reaction of pentaarylboroles withN-methylmorpholine-N-oxideviaa 1,1-insertion reaction.

An Oxygen Insertion Reaction of Osuloses

1965 ◽  
Vol 87 (14) ◽  
pp. 3273-3273 ◽  
Author(s):  
Ruth F. Nutt ◽  
Byron Arison ◽  
Frederick W. Holly ◽  
Edward Walton
Keyword(s):  
Insertion Reaction ◽  
Oxygen Insertion

scholarly journals The microbial metabolism of acetophenone. Metabolism of acetophenone and some chloroacetophenones by an Arthrobacter species

1975 ◽  
Vol 152 (2) ◽  
pp. 233-241 ◽  
Author(s):  
Roger E. Cripps
Keyword(s):  
Pure Culture ◽  
Sole Source ◽  
Insertion Reaction ◽  
Phenyl Acetate ◽  
Growth Substrate ◽  
Environmental Implications ◽  
Acetate Esterase ◽  
Oxygen Insertion ◽  
Arthrobacter Species ◽  
Hydrolysis Of

1. An organism that utilizes acetophenone as sole source of carbon and energy was isolated in pure culture and tentatively identified as an Arthrobacter sp. 2. Cell-free extracts of the acetophenone-grown organism contained an enzyme, acetophenone oxygenase, that catalysed an NADPH-dependent consumption of O2 in the presence of the growth substrate; approx. 1mol of O2 and 1mol of NADPH were consumed per mol of acetophenone oxidized. 3. Cell-free extracts also contained an enzyme capable of the hydrolysis of phenyl acetate to phenol and acetate. The amount of this esterase was increased markedly by growth on acetophenone. 4. The observed products of the acetophenone oxygenase reaction by crude cell-free extracts were phenol and acetate. However, inhibition of the phenyl acetate esterase by paraoxon resulted in the formation of phenyl acetate from acetophenone. 5. A degradative sequence is proposed in which acetophenone is metabolized by an oxygen-insertion reaction to form phenyl acetate. Further metabolism occurs by hydrolysis of this ester. 6. The organism and extracts were shown to metabolize chlorinated acetophenones. The environmental implications of this observation are discussed.

Mechanistic study of proliferation induced by Angelica sinensis in gastric epithelial cells

2001 ◽  
Vol 120 (5) ◽  
pp. A145-A145
Author(s):  
C CHO ◽  
Y YE ◽  
E LIU ◽  
V SHIN ◽  
N SHAM
Keyword(s):  
Epithelial Cells ◽  
Mechanistic Study ◽  
Angelica Sinensis ◽  
Gastric Epithelial Cells

Mechanistic study on the cardioprotective and chemosensitizing effects of a novel danshensu derivative

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
L Wang ◽  
L Shan ◽  
G Cui ◽  
Y Chen ◽  
J li ◽  
...  
Keyword(s):  
Mechanistic Study
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