Molecular Complexity as a Driver for Chemical Process Innovation in the Pharmaceutical Industry

2019 ◽  
Vol 84 (8) ◽  
pp. 4583-4603 ◽  
Author(s):  
Seb Caille ◽  
Sheng Cui ◽  
Margaret M. Faul ◽  
Steven M. Mennen ◽  
Jason S. Tedrow ◽  
...  
2020 ◽  
pp. 097639962094427
Author(s):  
Madan Dhanora ◽  
Ruchi Sharma ◽  
Walter G. Park

Technological innovations are positively associated with firms’ market performance. This study aims to examine the impact of product and process innovation on the market power of 168 Indian pharmaceutical firms during 2000–2013. We generate product and process patent stock to capture firm-level innovation activities. Findings of this study suggest that both product and process innovation positively influence firms’ market power. Results also reveal that MNEs enjoy more market power in the Indian pharmaceutical industry. Further, this study also highlights that there is a differential impact of firms’ product group on market power. This study concludes that patenting is a positive source of firm performance in the Indian pharmaceutical industry.


2020 ◽  
Vol 74 (5) ◽  
pp. 407-417
Author(s):  
Greg Mann ◽  
Frédéric V. Stanger

Enzymes have the potential to catalyse complex chemical reactions with unprecedented selectivity, under mild conditions in aqueous media. Accordingly, there is serious interest from the pharmaceutical industry to utilize enzymes as biocatalysts to produce medicines in an environmentally sustainable and economic manner. Prominent advances in the field of biotechnology have transformed this potential into a reality. Using modern protein engineering techniques, in a matter of months it is possible to evolve an enzyme, which fits the demands of a chemical process, or even to catalyse entirely novel chemistry. Consequently, biocatalysis is routinely applied throughout the pharmaceutical industry for a variety of applications, ranging from the manufacture of large volumes of high value blockbuster drugs to expanding the chemical space available for drug discovery.


2006 ◽  
Vol 106 (7) ◽  
pp. 2794-2810 ◽  
Author(s):  
A. Erik Rubin ◽  
Srinivas Tummala ◽  
Douglas A. Both ◽  
Chenchi Wang ◽  
Edward J. Delaney

ChemInform ◽  
2006 ◽  
Vol 37 (41) ◽  
Author(s):  
A. Erik Rubin ◽  
Srinivas Tummala ◽  
Douglas A. Both ◽  
Chenchi Wang ◽  
Edward J. Delaney

Author(s):  
Ivan Lugovoi ◽  
Dimitrios Andritsos ◽  
Claire Senot

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