One-Pot Synthesis of Indoles by a Sequential Ugi-3CR/Wittig Reaction Starting from Odorless Isocyanide-Substituted Phosphonium Salts

2017 ◽  
Vol 82 (5) ◽  
pp. 2772-2776 ◽  
Author(s):  
Yan-Mei Yan ◽  
Yong Rao ◽  
Ming-Wu Ding
Synlett ◽  
2021 ◽  
Author(s):  
Long Zhao ◽  
Mao-Lin Yang ◽  
Mei Sun ◽  
Ming-Wu Ding

A new one-pot Synthesis of 3-(1,2,3,4-tetrahydroisoquinolin-1-yl)- isoquinolin-1(2H)-ones by DEAD-promoted oxidative Ugi/Wittig reaction was developed. The sequential reactions of (2-carboxybenzyl)triphenylphosphonium salts, isocyanides and N-aryl-1,2,3,4-tetrahydroisoquinolines produced 3-(1,2,3,4-tetrahydroisoquinolin-1-yl)- isoquinolin-1(2H)-ones in moderate to good overall yields in the presence of DEAD and Et3N.


ChemInform ◽  
2015 ◽  
Vol 46 (26) ◽  
pp. no-no
Author(s):  
Kazuhiro Kobayashi ◽  
Naoki Matsumoto ◽  
Mika Nagashima ◽  
Hiroki Inouchi

2005 ◽  
Vol 46 (24) ◽  
pp. 4213-4217 ◽  
Author(s):  
Pradeep N.D. Singh ◽  
Rodney F. Klima ◽  
Sivaramakrishnan Muthukrishnan ◽  
Rajesh S. Murthy ◽  
Jagadis Sankaranarayanan ◽  
...  

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