Preparation of a C70 Bis-heterocyclic Derivative with High Chemio- and Regioselectivity

2015 ◽  
Vol 80 (10) ◽  
pp. 5315-5319 ◽  
Author(s):  
Hui-Lei Hou ◽  
Zong-Jun Li ◽  
Tao Sun ◽  
Xiang Gao
2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
Jakob Kljun ◽  
Saša Petriček ◽  
Dušan Žigon ◽  
Rosana Hudej ◽  
Damijan Miklavčič ◽  
...  

Novel ruthenium(III) complexes with histamine[RuCl4(dmso-S)(histamineH)]⋅O(1a) and[RuCl4(dmso-S)(histamineH)](1b) have been prepared and characterized by X-ray structure analysis. Their crystal structures are similar and show a protonated amino group on the side chain of the ligand which is not very common for a simple heterocyclic derivative such as histamine. Biological assays to test the cytotoxicity of the compound1bcombined with electroporation were performed to determine its potential for future medical applications in cancer treatment.


2017 ◽  
Vol 5 (5) ◽  
pp. 170-175
Author(s):  
AsstabraqMohsin Yasir ◽  
◽  
HaiderShanshool Mohammed ◽  

Author(s):  
Ratnamala P. Sonawane ◽  
Rahul R. Tripathi

Isatins are synthetically versatile substrates, where they can be used for the synthesis of a large variety of heterocyclic compounds. In this, a convenient method has been developed for the conversion of Indoles into Isatins and some heterocyclic derivative were synthesised such as 5- nitro-1H-indole-2,3-dione, 2-methylquinoline-4-carboxylic acid which may be used as raw material for drug synthesis. The general process utilizes the effective method for synthesis of Isatin from Indole is bromination and oxidation with an N-bromosuccinimide-dimethyl sulfoxide reagent. The nitration of Isatin at C-5 takes place by using KNO3, conc. H2SO4, 2-methylquinoline-4-caboxylic acid are usually obtained from pfitzinger reaction.


2020 ◽  
Author(s):  
Younes Lakhrissi ◽  
Mohamed Rbaa ◽  
Meriem Mequedade ◽  
Inssaf Berkiks ◽  
Joel Mague ◽  
...  

1986 ◽  
Vol 20 (3) ◽  
pp. 191-193 ◽  
Author(s):  
G. V. Dontsova ◽  
M. M. Konstantinova ◽  
A. A. Mandrugin ◽  
O. N. Rakhmanina ◽  
V. M. Fedoseev ◽  
...  

1986 ◽  
Vol 17 (30) ◽  
Author(s):  
G. V. DONTSOVA ◽  
M. M. KONSTANTINOVA ◽  
A. A. MANDRUGIN ◽  
O. N. RAKHMANINA ◽  
V. M. FEDOSEEV ◽  
...  

2011 ◽  
Vol 71-78 ◽  
pp. 1049-1052
Author(s):  
Ping Ouyang ◽  
Xian Ming Zhang

A heterocyclic derivative of 3-(N-mono-n-lurylaminomethyl) quinazolin-4-one was synthesized and its tribological behavior as an ashless additve without phosphorus and sulphur in liquid paraffin was evaluated using a four-ball tester. On the basis of the experimental results, the novel additive has been found to be quite effective as a potential additive in liquid paraffin. The nature of the film on the rubbed surface was investigated by scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS).


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