Synthesis of S-(3-aminobutyl)isothiourea and its heterocyclic derivative and radioprotective effect of these compounds

1986 ◽  
Vol 20 (3) ◽  
pp. 191-193 ◽  
Author(s):  
G. V. Dontsova ◽  
M. M. Konstantinova ◽  
A. A. Mandrugin ◽  
O. N. Rakhmanina ◽  
V. M. Fedoseev ◽  
...  
Keyword(s):  
Radioprotective Effect ◽  
Heterocyclic Derivative

scholarly journals Radioprotective Effect of Hesperidin: A Systematic Review

Medicina ◽  
2019 ◽  
Vol 55 (7) ◽  
pp. 370 ◽  
Author(s):  
Musa ◽  
Omyan ◽  
Esmaely ◽  
Shabeeb
Keyword(s):  
Clinical Trials ◽  
Survival Rates ◽  
Control Design ◽  
Case Control ◽  
Radioprotective Effect ◽  
Cellular Damage ◽  
Animal Cells ◽  
Meta Analyses ◽  
Late Side ◽  
Radioprotective Agent

Background and objectives: Ionizing radiation (IR) has been of immense benefit to man, especially for medical purposes (diagnostic imaging and radiotherapy). However, the risks of toxicity in healthy normal cells, leading to cellular damage as well as early and late side effects, have been major drawbacks. The aim of this study was to evaluate the radioprotective effect of hesperidin against IR-induced damage. Materials and Methods: The preferred reporting items for systematic reviews and meta-analyses (PRISMA) were applied in reporting this study. A search was conducted using the electronic databases PubMed, Scopus, Embase, Google Scholar, and www.ClinicalTrials.gov for information about completed or ongoing clinical trials. Results: From our search results, 24 studies involving rats, mice, and cultured human and animal cells were included. An experimental case—control design was used in all studies. The studies showed that the administration of hesperidin reduced oxidative stress and inflammation in all investigated tissues. Furthermore, it increased 30-day and 60-day survival rates and protected against DNA damage. The best radioprotection was obtained when hesperidin was administered before irradiation. Conclusions: The results of the included studies support the antioxidant, anti-inflammatory, and antiapoptotic abilities of hesperidin as a potential radioprotective agent against IR-induced damage. We recommend future clinical trials for more insights.

An investigation of the radioprotective effect of dietary antioxidants on isolated murine lymphocytes

1997 ◽  
Vol 25 (1) ◽  
pp. 136S-136S ◽  
Author(s):  
ETHEL S. GALLIGAN ◽  
SANDRA F. SWEETMAN ◽  
SEAN J. STRAIN ◽  
STEPHANIE R. McKEOWN
Keyword(s):  
Radioprotective Effect ◽  
Dietary Antioxidants

Radioprotective effect of dimethylsulfoxide on lactate dehydrogenase

1966 ◽  
Vol 53 (24) ◽  
pp. 702-702 ◽  
Author(s):  
W. Lohmann ◽  
A. J. Moss ◽  
S. L. Barker
Keyword(s):  
Lactate Dehydrogenase ◽  
Radioprotective Effect

Radioprotective Effect of Polyethylene Glycol

1986 ◽  
Vol 107 (1) ◽  
pp. 125 ◽  
Author(s):  
James Shaeffer ◽  
Karl A. Schellenberg ◽  
Cathy H. Seymore ◽  
Timothy E. Schultheiss ◽  
Anas M. El-Mahdi
Keyword(s):  
Polyethylene Glycol ◽  
Radioprotective Effect

Radioprotective effect of antioxidative flavonoids in γ-ray irradiated mice

1994 ◽  
Vol 15 (11) ◽  
pp. 2669-2672 ◽  
Author(s):  
Kayoko Shimoi ◽  
Shuichi Masuda ◽  
Michiyo Furugori ◽  
Sachiko Esaki ◽  
Naohide Kinae
Keyword(s):  
Radioprotective Effect ◽  
Γ Ray

The radioprotective effect of 5-thio-D-glucose on normal tissues in vivo

1982 ◽  
Vol 8 (3-4) ◽  
pp. 589-591 ◽  
Author(s):  
Vicki L. Schuman ◽  
Seymour H. Levitt ◽  
Chang W. Song
Keyword(s):  
Radioprotective Effect ◽  
Normal Tissues
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