Squaramide-Catalyzed Asymmetric Intramolecular Oxa-Michael Reaction of α,β-Unsaturated Carbonyls Containing Benzyl Alcohol: Construction of Chiral 1-Substituted Phthalans

2021 ◽  
Author(s):  
Eun Chae Son ◽  
Seung Yeon Kim ◽  
Sung-Gon Kim
Keyword(s):  
Benzyl Alcohol ◽  
Michael Reaction ◽  
Unsaturated Carbonyls

scholarly journals Carbonyl Composition and Electrophilicity in Vaping Emissions of Flavored and Unflavored E-Liquids

Toxics ◽  
2021 ◽  
Vol 9 (12) ◽  
pp. 345
Author(s):  
Jin Y. Chen ◽  
Alexa Canchola ◽  
Ying-Hsuan Lin
Keyword(s):  
Mass Spectrometry ◽  
Benzyl Alcohol ◽  
Interactive Effects ◽  
Dual Descriptor ◽  
Potential Health ◽  
Potential Health Risk ◽  
Reactivity Descriptors ◽  
Risk Effects ◽  
Unsaturated Carbonyls ◽  
Global Reactivity Descriptors

It has been demonstrated that propylene glycol (PG), vegetable glycerin (VG), and flavoring chemicals can thermally degrade to form carbonyls during vaping, but less is known about carbonyl emissions produced by transformation of flavoring chemicals and the interactive effects among e-liquid constituents. This study characterized carbonyl composition and levels in vaping emissions of PG-VG (e-liquid base solvents) and four e-liquid formulations flavored with trans-2-hexenol, benzyl alcohol, l-(-)-menthol, or linalool. Utilizing gas chromatography (GC)- and liquid chromatography (LC)-mass spectrometry (MS) methods, 14 carbonyls were identified and quantified. PG-VG emitted highest levels of formaldehyde, acetaldehyde, and acrolein. However, flavored e-liquids contributed to the production of a wider variety of carbonyls, with some carbonyls directly corresponding to the oxidation of alcohol moieties in flavoring compounds (e.g., trans-2-hexenol and benzyl alcohol transformed into trans-2-hexenal and benzaldehyde, respectively). Detections of formaldehyde-GSH and trans-2-hexenal-GSH adducts signify interactions of carbonyls with biological nucleophiles. The global reactivity descriptors (I, A, μ, η, and ω) and condensed Fukui parameters (fk0, fk−, fk+, and dual-descriptor) were computed to elucidate site reactivities of selected simple and α,β-unsaturated carbonyls found in vaping emissions. Overall, this study highlights carbonyl emissions and reactivities and their potential health risk effects associated with vaping.

Selective Oxidation of Benzyl Alcohol Catalyzed by Pd/PMO-SBA-15 Catalyst

2011 ◽  
Vol 31 (11) ◽  
pp. 1369-1373
Author(s):  
Cheng LIU ◽  
Rong TAN ◽  
Donghong YIN ◽  
Ningya YU ◽  
Yuxu ZHOU
Keyword(s):  
Benzyl Alcohol ◽  
Selective Oxidation ◽  
Oxidation Of Benzyl Alcohol

Phenolic Michael Reaction Acceptors: Combined Direct and Indirect Antioxidant Defenses Against Electrophiles and Oxidants

2007 ◽  
Vol 3 (3) ◽  
pp. 261-268 ◽  
Author(s):  
A. Dinkova-Kostova ◽  
J. Cheah ◽  
A. Samouilov ◽  
J. Zweier ◽  
R. Bozak ◽  
...  
Keyword(s):  
Michael Reaction ◽  
Antioxidant Defenses

Experimental and kinetic modeling study of benzyl alcohol pyrolysis

2021 ◽  
Vol 231 ◽  
pp. 111477
Author(s):  
Jin-Tao Chen ◽  
Zhi-Hao Jin ◽  
Wang Li ◽  
Kai-Ru Jin ◽  
Shu-Bao Song ◽  
...  
Keyword(s):  
Benzyl Alcohol ◽  
Kinetic Modeling ◽  
Modeling Study

scholarly journals Metal-free porous phosphorus-doped g-C3N4 photocatalyst achieving efficient synthesis of benzoin

RSC Advances ◽  
2021 ◽  
Vol 11 (21) ◽  
pp. 12682-12686
Author(s):  
Yuanjin Li ◽  
Shuhui Wang ◽  
Jin Wu ◽  
Qiuyan Wang ◽  
Changqiu Ma ◽  
...  
Keyword(s):  
Benzyl Alcohol ◽  
Conversion Rate ◽  
Oxygen Activation ◽  
Superoxide Radicals ◽  
Efficient Synthesis ◽  
Metal Free ◽  
Phosphorus Doped

Porous phosphorus-doped g-C3N4 (PCNT) has intensive oxygen activation ability to generate superoxide radicals, and can efficiently catalyze synthesis of benzoin from benzyl alcohol, with conversion rate and selectivity near to 100%.

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