Bacterial Fermentation of Water-Soluble Cellulose Acetate Raises Large-Bowel Acetate and Propionate and Decreases Plasma Cholesterol Concentrations in Rats

2018 ◽  
Vol 66 (45) ◽  
pp. 11909-11916 ◽  
Author(s):  
Tomomi Genda ◽  
Takashi Kondo ◽  
Shunsaku Sugiura ◽  
Shingo Hino ◽  
Shu Shimamoto ◽  
...  
2004 ◽  
Vol 92 (4) ◽  
pp. 607-615 ◽  
Author(s):  
Anthony R. Bird ◽  
Michelle Jackson ◽  
Roger A. King ◽  
Debra A. Davies ◽  
Sylvia Usher ◽  
...  

Hordeum vulgare var. Himalaya 292 is a new barley cultivar with altered starch synthesis and less total starch but more amylose, resistant starch (RS) and total and soluble NSP including β-glucan. To determine its nutritional potential, young pigs were fed diets containing stabilised wholegrain flours from either Himalaya 292, Namoi (a commercial barley), wheat bran or oat bran at equivalent dietary NSP concentrations for 21 d. Serum total cholesterol was significantly lowered by the Himalaya 292 diet relative to wheat bran, indicating that Himalaya 292 retained its hypocholesterolaemic potential. In all groups SCFA concentrations were highest in the proximal colon and decreased towards the rectum. Digesta pH was lowest in the proximal colon and highest in the distal colon. Large-bowel and faecal pH were significantly lower in the pigs fed the barley and oat diets, indicating greater bacterial fermentation. Caecal and proximal colonic pH was lowest and SCFA pools highest in the pigs fed Himalaya 292. Total and individual SCFA were lowest in the mid- and distal colon of the pigs fed Himalaya 292 or oat bran. These data suggest the presence of more RS in Himalaya 292 and suggest that its fermentation was rapid relative to transit. Differences in faecal and large-bowel anaerobic, aerobic, coliform and lactic acid bacteria were relatively small, indicating a lack of a specific prebiotic action. These data support the potential of this novel barley cultivar to improve health through plasma cholesterol reduction and increased large-bowel SCFA production.


2021 ◽  
Vol 156 ◽  
pp. 106255
Author(s):  
Taha El Assimi ◽  
Roko Blažic ◽  
Elvira Vidović ◽  
Mustapha Raihane ◽  
Abdellatif El Meziane ◽  
...  

2011 ◽  
Vol 239-242 ◽  
pp. 2855-2858 ◽  
Author(s):  
Hui Yun Zhou ◽  
Dong Ju Zhou ◽  
Chen Jie Fan ◽  
Xi Guang Chen

Chitosan/cellulose acetate multimicrospheres (CCAM) were prepared by the method of W/O/W emulsion with no toxic reagents and had the size interval of 200--280µm. It was investigated as an ideal alternative to enhancement the adsorption of water-soluble dyes from wastewater. The correlation coefficients of adsorption isotherm showed that the Freundlich model was comparable to the Langmuir model. The 1/n was lower than 1.0, indicating that malachite green was favorably adsorbed by CCAM. Furthermore, the amount of malachite green absorbed steeply increased with increasing time and reached plateau values within 2 h and increased with increasing of initial concentration of malachite green from 5 to 25 mg/g.


1993 ◽  
Vol 70 (2) ◽  
pp. 503-513 ◽  
Author(s):  
Yustinus Marsono ◽  
Richard J. Illman ◽  
Julie M. Clarke ◽  
Rodney P. Trimble ◽  
David L. Topping

Adult male pigs were fed on a diet containing (% of energy) fat 25 starch 55 from white rice and providing 20 g fibre/pig per d (diet WR). In two other groups rice bran was added to the diet to provide 43 g fibre/d. One group received the diet unmodified (diet RB), but in another (diet RO) heat-stabilized unrefined rice oil replaced the palm oil. In a further group brown rice replaced white rice and provided 37 g fibre/pig per d (diet BR). Plasma cholesterol concentrations were similar with diets WR, RB and BR. With diet RO the concentration was significantly lower than with diets WR and BR but was not different from diet RB. Plasma high-density-lipoprotein-cholesterol and plasma triacylglycerols were unaffected by diet. In all groups, digesta mass rose from the caecum to the proximal colon but fell in the distal colon. Diet WR gave the lowest digesta mass while diet BR gave a significantly higher mass along the large bowel length. RB- and RO-fed pigs had equal masses of digesta which were intermediate between BR- and WR-fed pigs at all sampling sites. Pools of individual and total volatile fatty acids (VFA) in the proximal large bowel were unaffected by diet. Pools of total and individual VFA in the median and distal colon were lowest with diets WR and RB and significantly higher with diet BR. In these regions of the colon pools of acetate in RO-fed pigs did not differ from those in the BR-fed group but were higher than in other groups. However, pools of propionate and butyrate with the RO diet were significantly lower than with diet BR and the same as with diets WR and RB. Portal venous VFA concentrations were unaffected by diet. The higher large bowel digesta masses and VFA with diet BR may reflect the escape of starch from the smallintestine.


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Mohamed El-Sakhawy ◽  
Samir Kamel ◽  
Ahmed Salama ◽  
Hebat-Allah Sarhan

Carboxymethyl cellulose acetate butyrate (CMCAB) has gained increasing importance in several fields, particularly in coating technologies and pharmaceutical research. CMCAB is synthesized by esterification of CMC sodium salt with acetic and butyric anhydrides. CMCAB mixed esters are relatively high molecular weight (MW) thermoplastic polymers with high glass transition temperatures (Tg). CMCAB ester is dispersible in water and soluble in a wide range of organic solvents, allowing varied opportunity to the solvent choice. It makes application of coatings more consistent and defect-free. Its ability to slow down the release rate of highly water-soluble compounds and to increase the dissolution of poorly soluble compounds makes CMCAB a unique and potentially valuable tool in pharmaceutical and amorphous solid dispersions (ASD) formulations.


2020 ◽  
Vol 28 (10) ◽  
pp. 1210-1216 ◽  
Author(s):  
Prasopchai Patrojanasophon ◽  
Siripran Tidjarat ◽  
Praneet Opanasopit ◽  
Tanasait Ngawhirunpat ◽  
Theerasak Rojanarata

Polymers ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 1734 ◽  
Author(s):  
Alfassi ◽  
Rein ◽  
Shpigelman ◽  
Cohen

Cellulose acetate is one of the most important cellulose derivatives. The use of ionic liquids in cellulose processing was recently found to act both as a solvent and also as a reagent. A recent study showed that cellulose dissolution in the ionic liquid 1-ethyl-3-methylimidazoliumacetate (EMIMAc) mixed with dichloromethane (DCM) resulted in controlled homogenous cellulose acetylation; yielding water-soluble cellulose acetate (WSCA). This research investigated the properties of cellulose acetate prepared in this manner, in an aqueous solution. The results revealed that WSCA fully dissolves in water, with no significant sign of molecular aggregation. Its conformation in aqueous solution exhibited a very large persistence length, estimated as over 10 nm. The WSCA exhibited surface activity, significantly reducing the surface tension of water. Because of the molecular dissolution of WSCA in water, augmented by its amphiphilicity, aqueous solutions of WSCA exhibited an overwhelmingly high rate of enzymatic hydrolysis.


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