Identification of New Anti-inflammatory Peptides from Zein Hydrolysate after Simulated Gastrointestinal Digestion and Transport in Caco-2 Cells

2018 ◽  
Vol 66 (5) ◽  
pp. 1114-1120 ◽  
Author(s):  
Qiufang Liang ◽  
Meram Chalamaiah ◽  
Xiaofeng Ren ◽  
Haile Ma ◽  
Jianping Wu
Keyword(s):  
Gastrointestinal Digestion ◽  
Simulated Gastrointestinal Digestion ◽  
Anti Inflammatory

The anti-inflammatory activity of peptides from simulated gastrointestinal digestion of preserved egg white in DSS-induced mouse colitis

2018 ◽  
Vol 9 (12) ◽  
pp. 6444-6454 ◽  
Author(s):  
Mengya Zhang ◽  
Yan Zhao ◽  
Na Wu ◽  
Yao Yao ◽  
Mingsheng Xu ◽  
...  
Keyword(s):  
Egg White ◽  
Inflammatory Activity ◽  
Gastrointestinal Digestion ◽  
Simulated Gastrointestinal Digestion ◽  
Anti Inflammatory

Peptides DEDTQAMPFR (DR-10), MLGATSL (ML-7), SLSFASR (SR-7), and MSYSAGF (MF-7) derived from simulated gastrointestinal digestion of preserved egg white (SGD-PEW) exerted anti-inflammatory effects on DSS-induced mouse colitis.

Anti-inflammatory and antioxidant effects of peptides released from germinated amaranth during in vitro simulated gastrointestinal digestion

2021 ◽  
Vol 343 ◽  
pp. 128394
Author(s):  
Eslim Sugey Sandoval-Sicairos ◽  
Ada Keila Milán-Noris ◽  
Diego Armando Luna-Vital ◽  
Jorge Milán-Carrillo ◽  
Alvaro Montoya-Rodríguez
Keyword(s):  
Gastrointestinal Digestion ◽  
Simulated Gastrointestinal Digestion ◽  
Anti Inflammatory ◽  
Antioxidant Effects

scholarly journals Simulated gastrointestinal digestion of Brazilian açaí seeds affects the content of flavan-3-ol derivatives, and their antioxidant and anti-inflammatory activities

Heliyon ◽  
2020 ◽  
Vol 6 (10) ◽  
pp. e05214
Author(s):  
Priscilla Siqueira Melo ◽  
Adna Prado Massarioli ◽  
Josy Goldoni Lazarini ◽  
Jackeline Cintra Soares ◽  
Marcelo Franchin ◽  
...  
Keyword(s):  
Gastrointestinal Digestion ◽  
Simulated Gastrointestinal Digestion ◽  
Anti Inflammatory

scholarly journals Antioxidant and Anti-Inflammatory Activity of Coffee Brew Evaluated after Simulated Gastrointestinal Digestion

Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4368
Author(s):  
Luigi Castaldo ◽  
Marianna Toriello ◽  
Raffaele Sessa ◽  
Luana Izzo ◽  
Sonia Lombardi ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Antioxidant Activity ◽  
High Resolution Mass Spectrometry ◽  
Mass Spectrometry Analysis ◽  
Total Phenolic ◽  
Gastrointestinal Digestion ◽  
Simulated Gastrointestinal Digestion ◽  
Wide Range ◽  
Anti Inflammatory ◽  
Ht 29

Coffee contains human health-related molecules, namely polyphenols that possess a wide range of pharmacological functions, and their intake is associated with reduced colon cancer risk. This study aimed to assess the changes in the anti-inflammatory and antioxidant activity of coffee after simulated gastrointestinal digestion. The evaluation of intracellular reactive oxygen species (ROS) levels in the HT-29 human colon cancer cell line and three in vitro spectrophotometric assays were performed to determine the antioxidant activity of the samples. Characterization of coffee composition was also assessed through a Q-Orbitrap high-resolution mass spectrometry analysis. The results highlighted that the levels of polyphenols in the digested coffee brews were higher than those of the non-digested ones. All assayed samples decreased the levels of intracellular ROS when compared to untreated cells, while digested coffee samples exhibited higher antioxidant capacity and total phenolic content than not-digested coffee samples. Digested coffee samples showed a higher reduction in interleukin-6 levels than the not-digested samples in lipopolysaccharide-stimulated HT-29 cells treated for 48 h and fewer cytotoxic effects in the MTT assay. Overall, our findings suggest that coffee may exert antioxidant and anti-inflammatory properties, and the digestion process may be able to release compounds with higher bioactivity.

Bioaccessibility of Tudela artichoke (Cynara scolymus cv. Blanca de Tudela) (poly)phenols: the effects of heat treatment, simulated gastrointestinal digestion and human colonic microbiota

2021 ◽  
Author(s):  
Maite Domínguez-Fernández ◽  
Iziar A. Ludwig ◽  
María-Paz De Peña ◽  
Concepción Cid
Keyword(s):  
Heat Treatment ◽  
Gastrointestinal Digestion ◽  
Cynara Scolymus ◽  
Simulated Gastrointestinal Digestion ◽  
Catabolic Activity ◽  
Colonic Microbiota ◽  
Positive Effect

Heat treatment exerts a positive effect on the bioaccessibility of artichoke (poly)phenols after gastrointestinal digestion. In the first 2 h of fermentation, native (poly)phenols were readily degraded by an important microbial catabolic activity.

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