Structure–Activity Relationship of Curcumin: Role of the Methoxy Group in Anti-inflammatory and Anticolitis Effects of Curcumin

2017 ◽  
Vol 65 (22) ◽  
pp. 4509-4515 ◽  
Author(s):  
Haixia Yang ◽  
Zheyuan Du ◽  
Weicang Wang ◽  
Mingyue Song ◽  
Katherine Sanidad ◽  
...  
Keyword(s):  
Methoxy Group ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Anti Inflammatory ◽  
Relationship Of

Tiliroside: Biosynthesis, Bioactivity and Structure activity relationship (SAR)- A review

2017 ◽  
Vol 6 (6) ◽  
pp. 343-348
Author(s):  
Lokadi Pierre Luhata ◽  
◽  
Wembi Gaston Luhata ◽  
◽  
Keyword(s):  
Acute Inflammation ◽  
Shikimate Pathway ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Coumaric Acid ◽  
Acid Moiety ◽  
Structure Activity ◽  
Starter Unit ◽  
Anti Inflammatory ◽  
Relationship Of

Tilirosides (TLD) are glycosidic flavonoids (GFD) from originating in plants that exhibit a range of bioactivities of great interest for healthcare: antioxidant, anti-microbial, antifungal, anti-diabetic and antihyperlipedemic, antiviral and cytotoxic, anti–inflammatory, anti-rheumatism, inhibition of neuroinflammation and acute inflammation and hepatoprotective activities. TLD are biosynthesized in plants in three main steps. First, the synthesis of the aglycone (a flavonoid) occurs, which follows the shikimate pathway with cinnamoylCoA as a starter unit. Second, there is the glucosylation of the aglycone using Uridine diphosphosugar (UDPglucose) as the agent for glycosylation. Finally, the coumaroyl part is added. The Structure Activity Relationship of TLD reveals that the addition of the para coumaric acid moiety considerably modifies their bioactivity.

scholarly journals Structure-Activity Relationship of Terpenes with Anti-Inflammatory Profile - A Systematic Review

2014 ◽  
Vol 115 (3) ◽  
pp. 244-256 ◽  
Author(s):  
Marilia Trindade de Santana Souza ◽  
Jackson Roberto Guedes da Silva Almeida ◽  
Adriano Antunes de Souza Araujo ◽  
Marcelo Cavalcante Duarte ◽  
Daniel Pens Gelain ◽  
...  
Keyword(s):  
Systematic Review ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Anti Inflammatory ◽  
Inflammatory Profile ◽  
Relationship Of
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