Gelatin Particle-Stabilized High-Internal Phase Emulsions for Use in Oral Delivery Systems: Protection Effect and in Vitro Digestion Study

2017 ◽  
Vol 65 (4) ◽  
pp. 900-907 ◽  
Author(s):  
Huan Tan ◽  
Lifeng Zhao ◽  
Sisi Tian ◽  
Hui Wen ◽  
Xiaojun Gou ◽  
...  
Keyword(s):  
Oral Delivery ◽  
In Vitro Digestion ◽  
Delivery Systems ◽  
Protection Effect ◽  
Internal Phase ◽  
Oral Delivery Systems

Development of antioxidant gliadin particle stabilized Pickering high internal phase emulsions (HIPEs) as oral delivery systems and the in vitro digestion fate

2018 ◽  
Vol 9 (2) ◽  
pp. 959-970 ◽  
Author(s):  
F. Z. Zhou ◽  
T. Zeng ◽  
S. W. Yin ◽  
C. H. Tang ◽  
D. B. Yuan ◽  
...  
Keyword(s):  
Lipid Oxidation ◽  
Chemical Stability ◽  
Oral Delivery ◽  
In Vitro Digestion ◽  
Delivery Systems ◽  
Algal Oil ◽  
Internal Phase ◽  
First Time ◽  
Oral Delivery Systems

In this paper, we demonstrate for the first time the use of gliadin particles to structure algal oil (rich in DHA) and to exert chemical stability against lipid oxidation via the Pickering high internal phase emulsion (HIPE) strategy.

In vitro Evaluation of Arabinoxylan Gels as an Oral Delivery System for Insulin

2012 ◽  
Vol 1487 ◽  
Author(s):  
E. Carvajal-Millan ◽  
C. Berlanga-Reyes ◽  
A. Rascón-Chu ◽  
A. L. Martínez-López ◽  
J. A. Márquez-Escalante ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Delivery System ◽  
Oral Delivery ◽  
Delivery Systems ◽  
Oral Delivery System ◽  
Apparent Diffusion ◽  
Oral Delivery Systems ◽  
Hydrolysis Of

ABSTRACTArabinoxylan gels are receiving increasing attention as oral delivery systems of biomolecules for therapeutic purposes. The aim of this research was to evaluate arabinoxylan gels as an oral delivery system for insulin, representing a painless therapy for diabetics. Gels at two concentrations of arabinoxylan were prepared (2.5 and 3.5 % w/v). One concentration of insulin (0.05 % w/v) entrapped in the arabinoxylan gels was investigated. At the end of gelation elasticity (G’) values were 11 and 20 for gels at 2.5 and 3.5% (w/v) in arabinoxylan, respectively. The presence of insulin in the gels did not affect the values of G’. The apparent diffusion coefficient for insulin decreased from 1.30 x 10-7 to 1.09 x 10-7 cm2/s when the concentration of arabinoxylan in the gel increased from 2.5 to 3.5% (w/v). The percentage of proteolysis for insulin entrapped in the gels at 2.5 and 3.5% in arabinoxylan (w/v) were 35 and 17%, respectively, in relation to 100% hydrolysis of insulin in solution. Results indicate that arabinoxylan gels could be potential candidates as oral delivery systems for insulin.

Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) Containing Rice Bran Oil for Enhanced Fenofibrate Oral Delivery: In Vitro Digestion, Ex Vivo Permeability, and In Vivo Bioavailability Studies

2020 ◽  
Vol 21 (6) ◽  
Author(s):  
Christina Karavasili ◽  
Ioannis I. Andreadis ◽  
Maria P. Tsantarliotou ◽  
Ioannis A. Taitzoglou ◽  
Paschalina Chatzopoulou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Rice Bran ◽  
Oral Delivery ◽  
Drug Delivery Systems ◽  
Rice Bran Oil ◽  
Ex Vivo ◽  
In Vitro Digestion ◽  
Delivery Systems

In vitro evaluation of glycol chitosan based formulations as oral delivery systems for efflux pump inhibition

2017 ◽  
Vol 166 ◽  
pp. 73-82 ◽  
Author(s):  
Delia Mandracchia ◽  
Adriana Trapani ◽  
Giuseppe Tripodo ◽  
Maria Grazia Perrone ◽  
Gaetano Giammona ◽  
...  
Keyword(s):  
Oral Delivery ◽  
Efflux Pump ◽  
Delivery Systems ◽  
Glycol Chitosan ◽  
In Vitro Evaluation ◽  
Efflux Pump Inhibition ◽  
Oral Delivery Systems

In vitro assessment of archaeosome stability for developing oral delivery systems

2000 ◽  
Vol 194 (1) ◽  
pp. 39-49 ◽  
Author(s):  
Girishchandra B Patel ◽  
Brian J Agnew ◽  
Lise Deschatelets ◽  
L.Perry Fleming ◽  
G.Dennis Sprott
Keyword(s):  
Oral Delivery ◽  
Delivery Systems ◽  
In Vitro Assessment ◽  
Oral Delivery Systems

In vitro evaluation of novel (nanoparticle) oral delivery systems allow selection of gut immunomodulatory formulations

2021 ◽  
Author(s):  
Ahmed Attaya ◽  
Kimberly Veenstra ◽  
Michael D. Welsh ◽  
Mukhtar Ahmed ◽  
Nessim Torabi-Pour ◽  
...  
Keyword(s):  
Oral Delivery ◽  
Delivery Systems ◽  
In Vitro Evaluation ◽  
Oral Delivery Systems ◽  
Selection Of
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