Functional Group-Dependent Screening of Organophosphate Esters (OPEs) and Discovery of an Abundant OPE Bis-(2-ethylhexyl)-phenyl Phosphate in Indoor Dust

2020 ◽  
Vol 54 (7) ◽  
pp. 4455-4464 ◽  
Author(s):  
Weikun Meng ◽  
Jianhua Li ◽  
Jinyou Shen ◽  
Yirong Deng ◽  
Robert J. Letcher ◽  
...  
Keyword(s):  
Functional Group ◽  
Indoor Dust ◽  
Organophosphate Esters ◽  
Phenyl Phosphate

scholarly journals Exposure to Phthalate and Organophosphate Esters via Indoor Dust and PM10 Is a Cause of Concern for the Exposed Saudi Population

2021 ◽  
Vol 18 (4) ◽  
pp. 2125
Author(s):  
Nadeem Ali ◽  
Nabil A. Alhakamy ◽  
Iqbal M. I. Ismail ◽  
Ehtisham Nazar ◽  
Ahmed Saleh Summan ◽  
...  
Keyword(s):  
Daily Intake ◽  
Indoor Dust ◽  
Air Conditioner ◽  
Lifetime Cancer Risk ◽  
Organophosphate Esters ◽  
Local Public Health ◽  
Suspended Particulate ◽  
Settled Dust ◽  
Filter Dust ◽  
Ethylhexyl Phthalate

In this study, we measured the occurrence of organophosphate esters (OPEs) and phthalates in the settled dust (floor and air conditioner filter dust) and in suspended particulate matter (PM10) from different microenvironments (households (n = 20), offices (n = 10) and hotels (n = 10)) of Jeddah, Saudi Arabia. Bis (2-Ethylhexyl) phthalate (DEHP) was the major pollutant (contributing >85% of total chemicals burden) in all types of indoor dust with a concentration up to 3,901,500 ng g−1. While dibutyl phthalate (DBP) and DEHP together contributed >70% in PM10 (1900 ng m−3), which indicate PM10 as a significant source of exposure for DBP and DEHP in different Saudi indoor settings. Tris (1-chloro-2-propyl) phosphate (TCPP) was the major OPE in PM10 with a concentration of up to 185 ng m−3 and the occurrence of OPEs in indoor dust varied in studied indoor settings. The estimated daily intake (EDI) of studied chemicals via dust ingestion and inhalation of PM10 was below the reference dose (RfD) of individual chemicals. However, estimated incremental lifetime cancer risk (ILCR) with moderate risk (1.5 × 10−5) for Saudi adults and calculated hazardous index (HI) of >1 for Saudi children from DEHP showed a cause of concern to the local public health.

Concentrations of organophosphate esters and brominated flame retardants in German indoor dust samples

2012 ◽  
Vol 14 (9) ◽  
pp. 2482 ◽  
Author(s):  
Sandra Brommer ◽  
Stuart Harrad ◽  
Nele Van den Eede ◽  
Adrian Covaci
Keyword(s):  
Flame Retardants ◽  
Brominated Flame Retardants ◽  
Indoor Dust ◽  
Organophosphate Esters

scholarly journals Organophosphate Esters in Children and Adolescents in Liuzhou City, China: Concentrations, Exposure Assessment and Predictors

2021 ◽  
Author(s):  
Meng Yu ◽  
Xiang Li ◽  
Bingqing Liu ◽  
Yaping Li ◽  
Ling Liu ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Maternal Education ◽  
Tap Water ◽  
Dietary Factors ◽  
Dermal Absorption ◽  
Indoor Dust ◽  
Organophosphate Esters ◽  
Water Drinking ◽  
Metabolite Concentrations ◽  
Diphenyl Phosphate

Abstract Dermal contact with dust is commonly considered an important pathway of exposure to organophosphate esters (OPEs), but the importance of OPE uptake from diet is unclear. Herein, we used hand wipes to estimate OPE exposure from indoor dust and examined whether urinary OPE metabolite concentrations were influenced by sociodemographic characteristics, OPE amount in hand wipes, and dietary factors. OPEs were measured in urine and hand wipes from 6–18-year old children and adolescents (n=929) in Liuzhou, China. Sociodemographic and dietary factors were obtained from questionnaire. Six OPE metabolites were detected in >70% of the urine samples, and seven OPEs were detected in >50% of the hand wipes. Estimated daily intakes (EDIs) were calculated using urinary OPE metabolites to investigate the total daily intake of OPEs, in which 0.36–10.1% of the total intake was attributed to the exposure from dermal absorption. In multivariate linear regression models, sex, age, and maternal education were significant predictors of urinary OPE metabolite concentrations. Urinary diphenyl phosphate (DPHP) is positively associated with its parent compounds 2-ethylhexyl-diphenyl phosphate (EHDPP) and triphenyl phosphate (TPHP) in hand wipes. High versus low vegetable intake was associated with a 23.7% higher DPHP (95% confidence interval (CI): 0.51%, 52.1%). Barreled water drinking was associated with a 30.4% (95% CI: 11.8%, 52.0%) increase in bis(1-chloro-2-propyl) 1-hydroxy-2-propyl phosphate (BCIPHIPP) compared to tap water drinking. Our results suggested the widespread exposure to OPEs in children and adolescents. In additional to dermal absorption, dietary intake may be an important exposure source of certain OPEs.

scholarly journals Organophosphate esters in indoor dust from 12 countries: Concentrations, composition profiles, and human exposure

2019 ◽  
Vol 133 ◽  
pp. 105178 ◽  
Author(s):  
Wenhui Li ◽  
Yu Wang ◽  
Alexandros G. Asimakopoulos ◽  
Adrian Covaci ◽  
Bondi Gevao ◽  
...  
Keyword(s):  
Human Exposure ◽  
Indoor Dust ◽  
Organophosphate Esters ◽  
Composition Profiles
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