Molecular Composition of Size-Fractionated Fulvic Acid-Like Substances Extracted from Spent Cooking Liquor and Its Relationship with Biological Activity

2019 ◽  
Vol 53 (24) ◽  
pp. 14752-14760 ◽  
Author(s):  
Yuanyuan Yao ◽  
Xiaoqi Wang ◽  
Yuechao Yang ◽  
Tianlin Shen ◽  
Chun Wang ◽  
...  
Keyword(s):  
Biological Activity ◽  
Fulvic Acid ◽  
Molecular Composition ◽  
Cooking Liquor

scholarly journals Isolation of bioactive substance from pure mumie

2014 ◽  
Vol 11 (2) ◽  
pp. 33-35
Author(s):  
T Enkh-Oyun ◽  
Ts Tsatsralt ◽  
J Bayarmaa
Keyword(s):  
Biological Activity ◽  
Humic Acid ◽  
Fulvic Acid ◽  
Fulvic Acids ◽  
Medical Applications ◽  
Asian Countries ◽  
Humic And Fulvic Acids ◽  
Highly Active ◽  
Agricultural Sciences ◽  
Bioactive Substance

Mumie contains humid and fulvic acids. For this study, pure mumie was fractionated into fulvic acid (FA) and humic acid (HA) fractions. Humic and Fulvic Acids are highly active bioregulators, and also they contain both macro- and micro-nutrients needed by human and animal bodies. Mumie is stone like material found in Mongolia at higher altitude, which has various medical applications in Mongolia and other Asian countries [2,3]. In the present study, the biological activity of mumie and its fractions was measured. Fractions were prepared according to the protocol described by I. A. Scheretkin and A.I. Khlebnikov. Both humic and fulvic acids can be obtained with the yields of 5.3% and 18.6 % respectively DOI: http://dx.doi.org/10.5564/mjas.v11i2.213 Mongolian Journal of Agricultural Sciences Vol.11(2) 2013 pp.33-35

Molecular composition of human luteinizing hormone: biological and immunological profiles of highly purified preparations after electrofocusing

1982 ◽  
Vol 94 (1) ◽  
pp. 29-36 ◽  
Author(s):  
A. A. Zaidi ◽  
M. H. Qazi ◽  
E. Diczfalusy
Keyword(s):  
Biological Activity ◽  
Luteinizing Hormone ◽  
Sucrose Density Gradient ◽  
Molecular Composition ◽  
Immunological Reactivity ◽  
Human Pituitary ◽  
Before And After ◽  
Pituitary Glands ◽  
Ph Range

Five highly purified human pituitary LH preparations (candidate preparations for a new International Reference Preparation (IRP) and coded A to E) and three highly purified commercial preparations (referred to as Kabi I, II and III) were fractionated by electrofocusing on a sucrose density gradient with ampholytes in the pH range of 3·5–10·0 The LH activity was monitored in each of the eluted fractions by an in-vitro bioassay and a radioimmunoassay procedure and the profiles of biological activity and immunoreactivity were compared with those of the first IRP of Human Pituitary Luteinizing Hormone for Immunoassay (code no. 68/40). The overall recovery of the biological activity after electrofocusing of the nine preparations ranged between 75 and 92% (mean 86%) and was higher (P < 0·05) than that of the immunological reactivity which varied between 71 and 94% (mean 79%). The profiles of the biological activity and immunological reactivity were in close agreement with each other in all preparations. Significant differences were, however, observed in the distribution of various molecular species between the currently used standard and the eight other highly purified preparations. The ratios of biological activity (B) to immunoreactivity (I) of preparation B and of the three Kabi preparations were significantly higher than those of the other five preparations, both before and after electrofocusing. After electrofocusing, a slight but significant (P < 0·05) rise in the B/I ratios was observed, suggesting that some biologically inactive immunoreactive material was removed during fractionation. All purified preparations lacked the characteristic 'acidic' human LH species which accompanies FSH and which is abundant in the IRP (69/104) and is also present in aqueous extracts of postmenopausal pituitary glands. A comparison of the electrofocusing profiles of the nine highly purified preparations with those of human LH from plasma and individual pituitary glands revealed marked differences, suggesting that the methods used for the purification of the hormone significantly altered its molecular composition.

Virus-Like Particles in a Human Breast Cancer: Structural Similarity to Previously Reported Particles

1973 ◽  
Vol 31 ◽  
pp. 378-379
Author(s):  
G. Kasnic ◽  
S. E. Stewart ◽  
C. Urbanski
Keyword(s):  
Breast Cancer ◽  
Biological Activity ◽  
Human Breast Cancer ◽  
Osteogenic Sarcoma ◽  
Human Tumor ◽  
Structural Similarity ◽  
Cell Tumor ◽  
Human Breast ◽  
Human Tumor Cell ◽  
Type Particle

We have reported the maturation of an intracisternal A-type particle in murine plasma cell tumor cultures and three human tumor cell cultures (rhabdomyosarcoma, lung adenocarcinoma, and osteogenic sarcoma) after IUDR-DMSO activation. In all of these studies the A-type particle seems to develop into a form with an electron dense nucleoid, presumably mature, which is also intracisternal. A similar intracisternal A-type particle has been described in leukemic guinea pigs. Although no biological activity has yet been demonstrated for these particles, on morphologic grounds, and by the manner in which they develop within the cell, they may represent members of the same family of viruses.

Effects of Vincristine on Endothelial Microtubules in the Spinal Cord

1976 ◽  
Vol 34 ◽  
pp. 58-59
Author(s):  
John L. Beggs ◽  
John D. Waggener ◽  
Wanda Miller
Keyword(s):  
Spinal Cord ◽  
Biological Activity ◽  
Horseradish Peroxidase ◽  
Transport Mechanism ◽  
Vasogenic Edema ◽  
Vesicular Transport ◽  
Close Proximity

Microtubules (MT) are versatile organelles participating in a wide variety of biological activity. MT involvement in the movement and transport of cytoplasmic components has been well documented. In the course of our study on trauma-induced vasogenic edema in the spinal cord we have concluded that endothelial vesicles contribute to the edema process. Using horseradish peroxidase as a vascular tracer, labeled endothelial vesicles were present in all situations expected if a vesicular transport mechanism was in operation. Frequently,labeled vesicles coalesced to form channels that appeared to traverse the endothelium. The presence of MT in close proximity to labeled vesicles sugg ested that MT may play a role in vesicular activity.

Isothiazol-3(2 H )-ones, Part I: Synthesis, Reactions and Biological Activity

2002 ◽  
Vol 23 (1) ◽  
pp. 79-121 ◽  
Author(s):  
Kathleen Taubert ◽  
Susanne Kraus ◽  
B&#x000E4;rbel Schulze
Keyword(s):  
Biological Activity ◽  
Synthesis Reactions

A spectroscopic study of soil fulvic acid composition after six-year applications of urban waste compost

Agronomie ◽  
2003 ◽  
Vol 23 (8) ◽  
pp. 719-724 ◽  
Author(s):  
Giovanni Gigliotti ◽  
Alceo Macchioni ◽  
Cristiano Zuccaccia ◽  
Pier Lodovico Giusquiani ◽  
Daniela Businelli
Keyword(s):  
Spectroscopic Study ◽  
Fulvic Acid ◽  
Acid Composition ◽  
Urban Waste
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