scholarly journals A Novel Method for Profiling and Quantifying Short- and Medium-Chain Chlorinated Paraffins in Environmental Samples Using Comprehensive Two-Dimensional Gas Chromatography–Electron Capture Negative Ionization High-Resolution Time-of-Flight Mass Spectrometry

2016 ◽  
Vol 50 (14) ◽  
pp. 7601-7609 ◽  
Author(s):  
Dan Xia ◽  
Lirong Gao ◽  
Minghui Zheng ◽  
Qichang Tian ◽  
Huiting Huang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Environmental Samples ◽  
Two Dimensional ◽  
Resolution Time ◽  
Electron Capture Negative Ionization ◽  
Flight Mass Spectrometry ◽  
Chlorinated Paraffins ◽  
Novel Method ◽  
Negative Ionization

scholarly journals Headspace Solid-Phase Microextraction Coupled to Comprehensive Two-Dimensional Gas Chromatography Time-of-Flight Mass Spectrometry for the Determination of Short-Chain Chlorinated Paraffins in Water Samples

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Nan Zhan ◽  
Feng Guo ◽  
Shuai Zhu ◽  
Zhu Rao
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Water Samples ◽  
Solid Phase Microextraction ◽  
Solid Phase ◽  
Short Chain ◽  
Two Dimensional ◽  
Flight Mass Spectrometry ◽  
Chlorinated Paraffins

Short-chain chlorinated paraffins (SCCPs) are a new type of persistent organic pollutants. In this work, a simple and effective method involving headspace solid-phase microextraction (HS-SPME) and comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry (GC × GC-TOF-MS) was developed and optimized for the determination of trace SCCPs in water samples. The key parameters related to extraction and separation efficiency were systematically optimized. The SCCP congener groups were best resolved using an Rxi-5Sil MS (30 m × 0.25 mm × 0.25 µm) column followed by an Rxi-17Sil MS (1.0 m × 0.15 mm × 0.15 µm) column; the optimum extraction conditions were achieved with a 100 µm polydimethylsiloxane SPME fiber, when a 10 mL water sample added with 3.6 g sodium chloride was incubated for 15 min at 90°C and then extracted during 60 min at 90°C and desorption at 260°C for 2 min. The proposed method showed good linearity in the concentration range of 0.2–20.0 µg/L with the determination coefficient greater than 0.995. The detection and quantification limits ranged from 0.06 to 0.13 µg/L and 0.18 to 0.40 µg/L, respectively, which are sufficient to meet the regulatory detection limits as set by most environmental regulations. The accuracy and precision of the method was also good, where the recoveries ranged from 82.5 to 95.4%, and intra- and interday precision was within 7.2% and 14.5%, respectively. The optimized method has been applied to the determination of SCCPs in ten freshwater samples of three different types.

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