Dose-Dependent Early Life Stage Toxicities in Xenopus laevis Exposed In Ovo to Selenium

2015 ◽  
Vol 49 (22) ◽  
pp. 13658-13666 ◽  
Author(s):  
Anita J. Massé ◽  
Jorgelina R. Muscatello ◽  
David M. Janz
Keyword(s):  
Xenopus Laevis ◽  
Early Life ◽  
Life Stage ◽  
Early Life Stage ◽  
In Ovo ◽  
Dose Dependent

Early Life-Stage Effects in Medaka (Oryzias latipes) Following in Ovo Exposure to Polyamine Biosynthetic Inhibitors

1994 ◽  
Vol 28 (3) ◽  
pp. 329-339 ◽  
Author(s):  
L.S. Ortego ◽  
A.C. Nimrod ◽  
W.T. Brehm ◽  
G.R. Parsons ◽  
W.H. Benson
Keyword(s):  
Early Life ◽  
Life Stage ◽  
Oryzias Latipes ◽  
Early Life Stage ◽  
In Ovo

scholarly journals Ultrastructural Alterations in Thyrocytes of Zebrafish (Danio rerio) after Exposure to Propylthiouracil and Perchlorate

2017 ◽  
Vol 45 (5) ◽  
pp. 649-662 ◽  
Author(s):  
Florian Schmidt ◽  
Raoul Wolf ◽  
Lisa Baumann ◽  
Thomas Braunbeck
Keyword(s):  
Danio Rerio ◽  
Early Life ◽  
Life Stage ◽  
Early Life Stage ◽  
Ultrastructural Level ◽  
Ultrastructural Changes ◽  
Histological Data ◽  
Dose Dependent ◽  
Sublethal Concentrations ◽  
Significant Mortality

Histopathology is a widely used approach to evaluate effects of endocrine-active chemicals in the thyroid. However, effects at an ultrastructural level have hardly been examined in fish thyroids. In the present study, zebrafish was exposed to sublethal concentrations of propylthiouracil (PTU; 0–50 mg/L) and perchlorate (PER; 0–5,000 µg/L) for 5 weeks in a modified early life–stage test. None of the treatments caused significant mortality (no observed effect concentrations for survival ≥50 mg/L [PTU] and ≥5,000 µg/L [PER]). PTU induced dose-dependent alterations in the rough endoplasmic reticulum (rER) in all exposure groups, whereas only the 2 highest PER exposure groups (500 and 5,000 µg/L) resulted in alterations of the rER. Both substances caused an increase in the numbers of lysosomes and mitochondria, with mitochondria displaying distorted cristae. Increased mitochondrial diameters were only observed in the PTU treatment. PER-exposed samples displayed an increase in apical microvilli. The highest PTU concentration (50 mg/L) showed first signs of cellular degeneration. Ultrastructural changes in zebrafish thyrocytes thus appear specific for different chemicals, most likely depending on their specific modes of action. Additional knowledge of subcellular changes in thyrocytes can help to better understand and interpret existing histological data in the future.

Age and growth of early life stage Atlantic Tarpon Megalops atlanticus from the northcentral Gulf of Mexico

2021 ◽  
Author(s):  
Patrick M. Graham ◽  
James S. Franks ◽  
Evan J. Anderson ◽  
Robert T. Leaf ◽  
Jason D. Tilley
Keyword(s):  
Gulf Of Mexico ◽  
Early Life ◽  
Life Stage ◽  
Early Life Stage ◽  
Age And Growth ◽  
Megalops Atlanticus ◽  
Atlantic Tarpon
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