Mixing Effect on Stoichiometric Diversity in Benzoic Acid–Sodium Benzoate Cocrystals

2019 ◽  
Vol 19 (3) ◽  
pp. 1576-1583 ◽  
Author(s):  
Tzu-Hsuan Chen ◽  
Kuan Lin Yeh ◽  
Chih Wei Chen ◽  
Hung Lin Lee ◽  
Yu Cheng Hsu ◽  
...  
1974 ◽  
Vol 57 (3) ◽  
pp. 719-720
Author(s):  
John D Weber

Abstract Sodium benzoate is retained on a Celite :1N sodium bicarbonate column while caffeine is eluted with ether and trapped on a second Celite: 1N H2S04 column. The sodium benzoate is recovered in the form of benzoic acid by elution with acetic acid in chloroform and the caffeine is eluted with chloroform. The concentrations in the eluates are directly measured by ultraviolet spectrophotometry.


CrystEngComm ◽  
2015 ◽  
Vol 17 (47) ◽  
pp. 9002-9006 ◽  
Author(s):  
Hung Lin Lee ◽  
Tu Lee

The ternary phase diagram for the direct assembly of a 2 : 1 co-crystal of benzoic acid–sodium benzoate was illustrated. Benzoic acid acted as a reactant and underwent neutralization to produce sodium benzoate. The excessive amount of benzoic acid as an API can interact with the product, sodium benzoate as another API, to undertake API–API co-crystallization by cooling.


1980 ◽  
Vol 63 (6) ◽  
pp. 959-963 ◽  
Author(s):  
B.F. Jenny ◽  
B.A. Costello ◽  
H.J. Van Dijk
Keyword(s):  

2012 ◽  
Vol 66 (3) ◽  
pp. 227-236 ◽  
Author(s):  
Tobias Gräber ◽  
Holger Kluge ◽  
Frank Hirche ◽  
Jiří Brož ◽  
Gabriele I. Stangl

1940 ◽  
Vol 5a (2) ◽  
pp. 148-163 ◽  
Author(s):  
H. L. A. Tarr ◽  
P. A. Sunderland

The effect of a number of chemical preservatives in inhibiting the bacterial "spoilage" of fresh fillets of certain species of Pacific coast fish has been studied. The preservatives were applied by dissolving them in sodium chloride brines in which the fish were immersed. Chloroform (0.7%) markedly improved the keeping quality of treated fish, while hydrogen peroxide (0.1%) had little effect. Sulphurous acid (0.1% SO2) considerably retarded bacterial "spoilage" but produced an unpleasant flavour. Hydrochloric acid (0.1%) slightly enhanced keeping quality but caused treated fillets to assume an unattractive appearance. Benzoic acid (0.1%) and sodium benzoate (0.1%) were quite effective, the former being slightly more active than the latter. Neither boric acid (0.1%) nor para-hydroxybenzoic acid ethyl ester (0.09%) were as efficient preservatives as benzoic acid or sodium benzoate in similar (per cent) concentration. Both sodium nitrite and potassium nitrite in 0.1% concentration caused a much greater inhibition in bacterial "spoilage" of fresh fillets than did sodium benzoate or benzoic acid, and the probable value of nitrites in fish preservation, as well as their influence on the colour of treated products, is discussed. The efficiency of a given preservative in different cases varied greatly, and in certain experiments a compound which normally exerted a favourable effect on keeping quality was without effect. The probable reason for this is discussed.


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