scholarly journals Experimental Study on the Influence of Excipients on the Heterogeneous Crystallization and Dissolution Properties of an Active Pharmaceutical Ingredient

2017 ◽  
Vol 18 (1) ◽  
pp. 338-350 ◽  
Author(s):  
Vivek Verma ◽  
Raghu V. G. Peddapatla ◽  
Clare M. Crowley ◽  
Abina M. Crean ◽  
Peter Davern ◽  
...  
Keyword(s):  
Experimental Study ◽  
Active Pharmaceutical Ingredient ◽  
Dissolution Properties ◽  
Heterogeneous Crystallization

An experimental study on polymorph control and continuous heterogeneous crystallization of carbamazepine

CrystEngComm ◽  
2019 ◽  
Vol 21 (34) ◽  
pp. 5076-5083 ◽  
Author(s):  
Chuntian Hu ◽  
Christopher J. Testa ◽  
Brianna T. Shores ◽  
Wei Wu ◽  
Khrystyna Shvedova ◽  
...  
Keyword(s):  
Experimental Study ◽  
Polymer Type ◽  
Heterogeneous Crystallization

Influences of superstaturation, stirring, anti-solvent, and polymer type on polymorph are investigated.

scholarly journals Formulation development of directly compressed Naproxen SR tablet using Kollidon SR and Avicel PH 102 polymer

2013 ◽  
Vol 2 (6) ◽  
pp. 112-114 ◽  
Author(s):  
Dilshad Yasmin ◽  
Md. Rashidur Rahman ◽  
Morshada Akter
Keyword(s):  
Active Pharmaceutical Ingredient ◽  
Pharmaceutical Journal ◽  
Average Weight ◽  
Physical Parameters ◽  
Direct Compression ◽  
Formulation Development ◽  
Compression Method ◽  
Drug Release Profile ◽  
Dissolution Properties ◽  
Rate Of Dissolution

Naproxen is a well-known non-steroidal anti-inflammatory drug (NSAID). This work has been done for developing a formulation of 280 mg sustained release (SR) tablet where 150 mg active pharmaceutical ingredient (Naproxen) were used along with other excipients like Kollidon SR, Avicel PH 102, Lactose MH, Povidone K 30 and Mg-Stearate. Naproxen SR tablet was prepared by direct compression method aiming to enhance its dissolution properties. The physical parameters (hardness, thickness, diameter, average weight and friability) and drug release profile of this tablet were evaluated. The hardness of tablets from F1 and F2 formulation were highest and rest of them was also satisfactory. F2 formulation did not meet the friability test. But rests of the formulations were acceptable which indicate that others formulations can handle pressure during storage, transportation and packaging. All the formulations released 90% of drug within 120 minutes except F4 formulation. Among the six formulations, release was prompt in F1 formulation because of usage of higher concentration of polymer Kollidon SR. The outcome of this study indicates that the rate of dissolution of Naproxen SR tablet can be considerably improved with Kollidon SR.DOI: http://dx.doi.org/10.3329/icpj.v2i6.14871 International Current Pharmaceutical Journal, May 2013, 2(6): 112-114

Experimental study on the restoration from a tilt-azimuth series for improvement in resolution

1995 ◽  
Vol 53 ◽  
pp. 636-637
Author(s):  
Norio Baba ◽  
Norihiko Ichise ◽  
Syunya Watanabe
Keyword(s):  
Experimental Study ◽  
Spherical Aberration ◽  
Incident Beam ◽  
Optical Parameters ◽  
Beam Tilting ◽  
Illumination Method ◽  
Restoration Method ◽  
Illumination Mode

The tilted beam illumination method is used to improve the resolution comparing with the axial illumination mode. Using this advantage, a restoration method of several tilted beam images covering the full azimuthal range was proposed by Saxton, and experimentally examined. To make this technique more reliable it seems that some practical problems still remain. In this report the restoration was attempted and the problems were considered. In our study, four problems were pointed out for the experiment of the restoration. (1) Accurate beam tilt adjustment to fit the incident beam to the coma-free axis for the symmetrical beam tilting over the full azimuthal range. (2) Accurate measurements of the optical parameters which are necessary to design the restoration filter. Even if the spherical aberration coefficient Cs is known with accuracy and the axial astigmatism is sufficiently compensated, at least the defocus value must be measured. (3) Accurate alignment of the tilt-azimuth series images.

An Experimental Study of Some Properties of Stuttered Words

1962 ◽  
Vol 5 (4) ◽  
pp. 387-394 ◽  
Author(s):  
Bruce Quarrington ◽  
Jerome Conway ◽  
Nathan Siegel
Keyword(s):  
Experimental Study

Experimental study of total body washout employing extracorporeal circulation and hypothermia

1974 ◽  
Vol 126 (2) ◽  
pp. 243-248
Author(s):  
A WAKABAYASHI ◽  
T KUBO ◽  
K CHARNEY ◽  
Y NAKAMURA ◽  
J CONNOLLY
Keyword(s):  
Experimental Study ◽  
Extracorporeal Circulation ◽  
Total Body

Gastric Freezing: An Experimental Study

1963 ◽  
Vol 45 (3) ◽  
pp. 374-383 ◽  
Author(s):  
Donald C. McIlrath ◽  
George A. Hallenbeck ◽  
Hubert A. Allen ◽  
Charles V. Mann ◽  
Edward J. Baldes ◽  
...  
Keyword(s):  
Experimental Study
Sign in / Sign up

Export Citation Format

Share Document