Gas Chromatography with In Situ Catalytic Hydrogenolysis and Flame Ionization Detection for the Direct Measurement of Formaldehyde and Acetaldehyde in Challenging Matrices

2018 ◽  
Vol 90 (23) ◽  
pp. 13855-13859 ◽  
Author(s):  
Jim Luong ◽  
Xiuhan Yang ◽  
Yujuan Hua ◽  
Peilin Yang ◽  
Ronda Gras
Keyword(s):  
Gas Chromatography ◽  
Direct Measurement ◽  
Flame Ionization Detection ◽  
Ionization Detection ◽  
Flame Ionization ◽  
Catalytic Hydrogenolysis

Metal 3D‐printed catalytic jet and flame ionization detection for in situ trace carbon oxides analysis by gas chromatography

2019 ◽  
Vol 42 (17) ◽  
pp. 2826-2834 ◽  
Author(s):  
Ronda Gras ◽  
Yujuan Hua ◽  
Jim Luong ◽  
Peiqi Qiao ◽  
Xiuhan Grace Yang ◽  
...  
Keyword(s):  
Gas Chromatography ◽  
Flame Ionization Detection ◽  
Carbon Oxides ◽  
Ionization Detection ◽  
Flame Ionization ◽  
3D Printed

Study of Endocrine Disruptors in the Sediment of a South Brazilian River

2015 ◽  
Vol 1120-1121 ◽  
pp. 862-866
Author(s):  
Irajá Do Nascimento ◽  
Nathália Christine Vieceli ◽  
Michele Schmitz ◽  
Fernanda Glaeser
Keyword(s):  
Gas Chromatography ◽  
Bisphenol A ◽  
Endocrine Disruptors ◽  
River Sediment ◽  
Flame Ionization Detection ◽  
River Contamination ◽  
Ionization Detection ◽  
Flame Ionization ◽  
Organic Extracts ◽  
Ethylhexyl Phthalate

This study investigated the occurrence of di (2-ethylhexyl) phthalate (DEHP) di-n-butylphthalate (DBP) and bisphenol A (BPA) in river sediment. The samples were collected from three selected points and extracted by sonication, using n-hexane and ethanol. The organic extracts were analyzed by gas chromatography with flame ionization detection (GC/FID). DBP and BPA were not detected. The average concentrations of DEHP range from 0.72 (±0.04) to 27.90 (± 3.05) ng g-1 of sediment. The best solvent for the extractions was n-hexane. However ethanol also shows good extraction yields of DEHP. These results showed an important anthropic contribution for the river contamination by endocrine disruptors.

The secretion of ibuprofen metabolites interferes with the capillary chromatography of urinary homovanillic acid and 4-hydroxy-3-methoxymandelic acid in neuroblastoma diagnosis

2005 ◽  
Vol 43 (2) ◽  
Author(s):  
Isabella Levreri ◽  
Ubaldo Caruso ◽  
Franca Deiana ◽  
Antonella Buoncompagni ◽  
Bruno De Bernardi ◽  
...  
Keyword(s):  
Gas Chromatography ◽  
Capillary Gas Chromatography ◽  
Homovanillic Acid ◽  
Urine Samples ◽  
Gas Chromatography Mass Spectrometry ◽  
Catecholamine Metabolism ◽  
Flame Ionization Detection ◽  
Trimethylsilyl Ester ◽  
Ionization Detection ◽  
Flame Ionization

AbstractNeuroblastoma is the most common extracranial solid tumor in children. Abnormal secretion of catechol-amines in tissues and body fluids allows for the differential diagnosis of neuroblastoma from other neoplasms and its distinction from non-neoplastic inflammatory diseases. This is achieved by assaying homovanillic acid and 4-hydroxy-3-methoxymandelic acid, the catabolites of catecholamine metabolism. In the course of an evaluation of children with suspected neuroblastoma, homovanillic acid and 4-hydroxy-3-methoxymandelic acid were analyzed in urine samples by capillary gas chromatography with flame ionization detection after extraction and derivatization of these compounds as trimethylsilyl derivatives. In three urine samples a significant increase in biogenic amines was observed, but these results were not confirmed by thin-layer chromatography. Patient history revealed that these children had been treated with ibuprofen, an analgesic and anti-inflammatory drug. To verify how ibuprofen or its metabolites may have interfered with capillary gas chromatography with flame ionization detection, we analyzed the same samples by capillary gas chromatography-mass spectrometry. In urine samples from patients on the drug, the presence of a peak identified as the trimethylsilyl ester of hydroxyibuprofen, which had the same retention time as 4-hydroxy-3-methoxymandelic acid, was found to interfere with the capillary gas chromatography with flame ionization detection analysis of the metabolite. This interference must be taken into account during the laboratory diagnosis of neuroblastoma.

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