Immunoelectrodes in Protein Detection:  Comparison between Glassy Carbon and a Semimetallic Ni/P Thin Film as Binding Support. Biological Applications

1998 ◽  
Vol 70 (23) ◽  
pp. 5072-5078 ◽  
Author(s):  
Pascal Darbon ◽  
Vincent Michel ◽  
François Math ◽  
Hervé Giorgi ◽  
Francis Machizaud
2010 ◽  
Vol 1272 ◽  
Author(s):  
Sang Hoon Lee ◽  
Jangbae Jeon ◽  
Sang Ho Lee ◽  
Moon J. Kim

AbstractHere we report an epoch-making simple fabrication for wrinkle formation. The present wrinkle formation process is a solution for controlling the area, shape and direction of wrinkle area by forming wrinkles on the liquid state polydimethylsiloxane directly exposed to sputtered metal particles in the low vacuum plasma chamber in various vacuum states and deposition conditions. Also the process allows us to make extremely flexible metal thin film electrode with approved adhesion. These bring us possibilities of actual electrical and biological applications.


2019 ◽  
Vol 19 (7) ◽  
pp. 4116-4122
Author(s):  
Vadivel Selvamani ◽  
Venkatachalam Rajagopal ◽  
Noel Nesakumar ◽  
David Velayutham ◽  
Vembu Suryanarayanan

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Surabhi Nimbalkar ◽  
Erwin Fuhrer ◽  
Pedro Silva ◽  
Tri Nguyen ◽  
Martin Sereno ◽  
...  

AbstractThe recent introduction of glassy carbon (GC) microstructures supported on flexible polymeric substrates has motivated the adoption of GC in a variety of implantable and wearable devices. Neural probes such as electrocorticography and penetrating shanks with GC microelectrode arrays used for neural signal recording and electrical stimulation are among the first beneficiaries of this technology. With the expected proliferation of these neural probes and potential clinical adoption, the magnetic resonance imaging (MRI) compatibility of GC microstructures needs to be established to help validate this potential in clinical settings. Here, we present GC microelectrodes and microstructures—fabricated through the carbon micro-electro-mechanical systems process and supported on flexible polymeric substrates—and carry out experimental measurements of induced vibrations, eddy currents, and artifacts. Through induced vibration, induced voltage, and MRI experiments and finite element modeling, we compared the performances of these GC microelectrodes against those of conventional thin-film platinum (Pt) microelectrodes and established that GC microelectrodes demonstrate superior magnetic resonance compatibility over standard metal thin-film microelectrodes. Specifically, we demonstrated that GC microelectrodes experienced no considerable vibration deflection amplitudes and minimal induced currents, while Pt microelectrodes had significantly larger currents. We also showed that because of their low magnetic susceptibility and lower conductivity, the GC microelectrodes caused almost no susceptibility shift artifacts and no eddy-current-induced artifacts compared to Pt microelectrodes. Taken together, the experimental, theoretical, and finite element modeling establish that GC microelectrodes exhibit significant MRI compatibility, hence demonstrating clear clinical advantages over current conventional thin-film materials, further opening avenues for wider adoption of GC microelectrodes in chronic clinical applications.


2017 ◽  
Vol 2 (1) ◽  
pp. 1700081 ◽  
Author(s):  
Maria Vomero ◽  
Elisa Castagnola ◽  
Juan S. Ordonez ◽  
Stefano Carli ◽  
Elena Zucchini ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document