Complexes [Cu(i)(2,4-dimethylphenoxy)2]− (A) and [Cu(ii)(2,4-dimethylphenoxy)2(p-tolyl)]− (B) were observed by in situ ESI-MS analysis of the ligand free copper(i)-catalyzed C–O coupling reaction using Cs2CO3 under the catalytic reaction conditions.
A novel integrated platform for quantitative proteome analysis was established by the combination of IMER, for digestion and in situ18O labeling, and nanoRPLC-ESI-MS/MS.
The integration of an anti-cancer drug bicalutamide with tissue-specific supramolecular self-assembly of peptide derivatives yielded in situ hydrogelation at prostate tissue for smart drug release.
Stimuli-responsive in situ self-assembly of small molecule probes into nanostructures has been promising for the construction of molecular probes for in vivo imaging.
In Situ and Multisubstrate Detection of Elastase Enzymatic Activity External to Microdialysis Sampling Probes Using LC−ESI-MS