Sensitive Single Particle Method for Characterizing Rapid Rotational and Translational Diffusion and Aspect Ratio of Anisotropic Nanoparticles and Its Application in Immunoassays

2013 ◽  
Vol 85 (20) ◽  
pp. 9433-9438 ◽  
Author(s):  
Bocheng Zhang ◽  
Tao Lan ◽  
Xiangyi Huang ◽  
Chaoqing Dong ◽  
Jicun Ren
Author(s):  
Tao Zhang ◽  
Wenxiong Huang

AbstractCrushing characteristics of single particles are the basis of granular material simulation with discrete element method (DEM). To improve the universality and precision of crushable DEM model, inhomogeneous stiffness and strength properties are introduced into the bonded particle method, with which the Weibull distribution and size effect of particle strength can be reproduced without deleting elementary balls. The issues of particle strength and carrying capacity under complex contact conditions are investigated in this work by symmetric loading tests, asymmetric loading tests, and ball–ball loading tests. Results of numerical experiments indicate that particle carrying capacity is significantly influenced by coordination numbers, the symmetry of contact points, as well as the relative size of its neighbors. Contact conditions also show impact on single-particle crushing categories and the origin position of inner particle cracks. The existing stress indexes and assumptions of particle crushing criterion are proved to be inappropriate for general loading cases. Both the inherent inhomogeneity and contact conditions of particles should be taken into consideration in the simulation of granular materials.


2019 ◽  
Vol 14 (1) ◽  
pp. 18-00539-18-00539
Author(s):  
Tetsuro TSUJI ◽  
Kentaro DOI ◽  
Satoyuki KAWANO

2015 ◽  
Vol 36 (9-10) ◽  
pp. 1164-1171 ◽  
Author(s):  
Gaurav Goyal ◽  
Rafael Mulero ◽  
Jamel Ali ◽  
Armin Darvish ◽  
Min Jun Kim

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