Sensitive and Homogeneous Protein Detection Based on Target-Triggered Aptamer Hairpin Switch and Nicking Enzyme Assisted Fluorescence Signal Amplification

2012 ◽  
Vol 84 (8) ◽  
pp. 3507-3513 ◽  
Author(s):  
Liyun Xue ◽  
Xiaoming Zhou ◽  
Da Xing
Keyword(s):  
Signal Amplification ◽  
Protein Detection ◽  
Fluorescence Signal ◽  
Fluorescence Signal Amplification ◽  
Nicking Enzyme

Proximity-dependent protein detection based on enzyme-assisted fluorescence signal amplification

2014 ◽  
Vol 51 ◽  
pp. 255-260 ◽  
Author(s):  
Yuyu Tan ◽  
Qiuping Guo ◽  
Xiayu Zhao ◽  
Xiaohai Yang ◽  
Kemin Wang ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Protein Detection ◽  
Fluorescence Signal ◽  
Fluorescence Signal Amplification ◽  
Dependent Protein

Sensitive mutant DNA biomarker detection based on magnetic nanoparticles and nicking endonuclease assisted fluorescence signal amplification

RSC Advances ◽  
2015 ◽  
Vol 5 (26) ◽  
pp. 20020-20024 ◽  
Author(s):  
Na Li ◽  
Zhong Feng Gao ◽  
Bei Hua Kang ◽  
Nian Bing Li ◽  
Hong Qun Luo
Keyword(s):  
Magnetic Nanoparticles ◽  
Signal Amplification ◽  
Fluorescence Signal ◽  
Biomarker Detection ◽  
Background Signal ◽  
Sensitive Mutant ◽  
Nicking Endonuclease ◽  
Low Background ◽  
Target Dna ◽  
Fluorescence Signal Amplification

Amplified fluorescence target DNA detection was developed combining nicking endonuclease assisted target recycling and magnetic nanoparticles with low background signal.

Fluorescence Signal Amplification by Cation Exchange in Ionic Nanocrystals

2009 ◽  
Vol 121 (9) ◽  
pp. 1616-1619 ◽  
Author(s):  
Jishan Li ◽  
Tierui Zhang ◽  
Jianping Ge ◽  
Yadong Yin ◽  
Wenwan Zhong
Keyword(s):  
Cation Exchange ◽  
Signal Amplification ◽  
Fluorescence Signal ◽  
Fluorescence Signal Amplification

scholarly journals A new two-mode fluorescence signal amplification strategy for protease activity assay based on graphene oxide

RSC Advances ◽  
2017 ◽  
Vol 7 (76) ◽  
pp. 47983-47989 ◽  
Author(s):  
Fangfang Wang ◽  
Jie Gao ◽  
Jianwei Zhao ◽  
Wenyue Zhang ◽  
Jie Bai ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Signal Amplification ◽  
Protease Activity ◽  
Fluorescence Signal ◽  
Activity Assay ◽  
Fluorescence Signal Amplification ◽  
Amplification Strategy

A new graphene oxide-based two-mode fluorescence signal amplification strategy for the detection of protease activity has been established.

A supersandwich fluorescence in situ hybridization strategy for highly sensitive and selective mRNA imaging in tumor cells

2016 ◽  
Vol 52 (2) ◽  
pp. 370-373 ◽  
Author(s):  
Jin Huang ◽  
He Wang ◽  
Xiaohai Yang ◽  
Yanjing Yang ◽  
Ke Quan ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Fluorescence In Situ Hybridization ◽  
Tumor Cells ◽  
Signal Amplification ◽  
Fluorescence Signal ◽  
Target Mrna ◽  
Highly Sensitive ◽  
Fluorescence Signal Amplification

This strategy uses two fluorophore-labeled signal probes to generate a supersandwich product, which in turn generates numerous signal probes located at the target mRNA position, resulting in thein situfluorescence signal amplification.

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