Valence Parity to Distinguish c′ and z•Ions from Electron Capture Dissociation/Electron Transfer Dissociation of Peptides: Effects of Isomers, Isobars, and Proteolysis Specificity

2011 ◽  
Vol 83 (20) ◽  
pp. 8024-8028 ◽  
Author(s):  
Yuan Mao ◽  
Jeremiah D. Tipton ◽  
Greg T. Blakney ◽  
Christopher L. Hendrickson ◽  
Alan G. Marshall
Keyword(s):  
Electron Transfer ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Electron Transfer Dissociation

Protein O-glycosylation analysis

2012 ◽  
Vol 393 (8) ◽  
pp. 687-708 ◽  
Author(s):  
Gerhild Zauner ◽  
Radoslaw P. Kozak ◽  
Richard A. Gardner ◽  
Daryl L. Fernandes ◽  
André M. Deelder ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Electron Transfer Dissociation ◽  
Detection Methods ◽  
Glycan Analysis ◽  
Attachment Sites ◽  
Fragmentation Techniques

Abstract This review provides an overview on the methods available for analysis of O-glycosylation. Three major themes are addressed: analysis of released O-glycans including different O-glycan liberation, derivatization, and detection methods; analysis of formerly O-glycosylated peptides yielding information on O-glycan attachment sites; analysis of O-glycopeptides, representing by far the most informative but also most challenging approach for O-glycan analysis. Although there are various techniques available for the identification of O-linked oligosaccharides, the focus here is on MS fragmentation techniques such as collision-induced fragmentation, electron capture dissociation, and electron transfer dissociation. Finally, the O-glycan analytical challenges that need to be met will be discussed.

scholarly journals Probing the Mechanism of Electron Capture and Electron Transfer Dissociation Using Tags with Variable Electron Affinity

2009 ◽  
Vol 131 (15) ◽  
pp. 5444-5459 ◽  
Author(s):  
Chang Ho Sohn ◽  
Cheol K. Chung ◽  
Sheng Yin ◽  
Prasanna Ramachandran ◽  
Joseph A. Loo ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Electron Capture ◽  
Electron Affinity ◽  
Electron Transfer Dissociation

scholarly journals Charge remote fragmentation in electron capture and electron transfer dissociation

2010 ◽  
Vol 21 (4) ◽  
pp. 646-656 ◽  
Author(s):  
Xiaojuan Li ◽  
Cheng Lin ◽  
Liang Han ◽  
Catherine E. Costello ◽  
Peter B. O’Connor
Keyword(s):  
Electron Transfer ◽  
Electron Capture ◽  
Electron Transfer Dissociation ◽  
Charge Remote Fragmentation
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