Design of Aptamer-Based Sensing Platform Using Triple-Helix Molecular Switch

2011 ◽  
Vol 83 (17) ◽  
pp. 6586-6592 ◽  
Author(s):  
Jing Zheng ◽  
Jishan Li ◽  
Ying Jiang ◽  
Jianyu Jin ◽  
Kemin Wang ◽  
...  
Keyword(s):  
Triple Helix ◽  
Molecular Switch ◽  
Sensing Platform

A signal on aptamer-based electrochemical sensing platform using a triple-helix molecular switch

2014 ◽  
Vol 6 (16) ◽  
pp. 6294-6300 ◽  
Author(s):  
Yudan Du ◽  
Yinfei Mao ◽  
Xiaoxiao He ◽  
Kemin Wang ◽  
Genping Yan ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Triple Helix ◽  
Molecular Switch ◽  
Electrochemical Sensing ◽  
Label Free ◽  
Sensing Platform ◽  
Aptamer Sequence

A signal on aptamer-based electrochemical sensing platform was demonstrated by taking advantage of a triple-helix molecular switch, which contained a label-free target specific aptamer sequence and a hairpin-shaped structured signal transduction probe.

A sensitive SERS assay for detecting proteins and nucleic acids using a triple-helix molecular switch for cascade signal amplification

2014 ◽  
Vol 50 (66) ◽  
pp. 9409-9412 ◽  
Author(s):  
Sujuan Ye ◽  
Yanying Wu ◽  
Wen Zhang ◽  
Na Li ◽  
Bo Tang
Keyword(s):  
Nucleic Acids ◽  
Signal Amplification ◽  
Triple Helix ◽  
Detection System ◽  
Molecular Switch ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Multiple Cycle ◽  
Enhanced Raman Scattering

A sensitive surface-enhanced Raman scattering (SERS) detection system is developed for proteins and nucleic acids based on a triple-helix molecular switch for multiple cycle signal amplification.

Triple-helix molecular-switch-actuated exponential rolling circular amplification for ultrasensitive fluorescence detection of miRNAs

The Analyst ◽  
2019 ◽  
Vol 144 (17) ◽  
pp. 5245-5253 ◽  
Author(s):  
Yihan Zhao ◽  
Yu Wang ◽  
Su Liu ◽  
Chonglin Wang ◽  
Jiaxu Liang ◽  
...  
Keyword(s):  
Fluorescence Detection ◽  
Triple Helix ◽  
High Efficiency ◽  
Molecular Switch ◽  
Ultrasensitive Detection ◽  
Fluorescent Biosensing

We have developed a rapid and high-efficiency fluorescent biosensing platform based on triple-helix molecular-switch (THMS)-actuated exponential rolling circular amplification (RCA) strategy for the ultrasensitive detection of miR-21.

A versatile signal-on electrochemical biosensor for Staphylococcus aureus based on triple-helix molecular switch

2021 ◽  
Vol 326 ◽  
pp. 128842
Author(s):  
Rongfeng Cai ◽  
Zhongwen Zhang ◽  
Haohan Chen ◽  
Yaping Tian ◽  
Nandi Zhou
Keyword(s):  
Staphylococcus Aureus ◽  
Triple Helix ◽  
Electrochemical Biosensor ◽  
Molecular Switch

A triple-helix molecular switch photoelectrochemical biosensor for ultrasensitive microRNA detection based on position-controllable CdS//CdTe signal enhancement and switching

2020 ◽  
Vol 56 (19) ◽  
pp. 2909-2912 ◽  
Author(s):  
Wenchao Geng ◽  
Ruiying Yang
Keyword(s):  
Triple Helix ◽  
Molecular Switch ◽  
Signal Enhancement ◽  
Microrna Detection ◽  
Photoelectrochemical Biosensor

A triple-helix molecular switch photoelectrochemical biosensor is developed for ultrasensitive microRNA detection based on position-controllable CdS//CdTe signal enhancement and switching.

Triple-Helix Molecular Switch Electrochemical Ratiometric Biosensor for Ultrasensitive Detection of Nucleic Acids

2017 ◽  
Vol 89 (17) ◽  
pp. 8830-8835 ◽  
Author(s):  
Erhu Xiong ◽  
Zhenzhen Li ◽  
Xiaohua Zhang ◽  
Jiawan Zhou ◽  
Xiaoxia Yan ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Triple Helix ◽  
Molecular Switch ◽  
Ultrasensitive Detection

A novel colorimetric triple-helix molecular switch aptasensor based on peroxidase-like activity of gold nanoparticles for ultrasensitive detection of lead(ii)

RSC Advances ◽  
2015 ◽  
Vol 5 (54) ◽  
pp. 43508-43514 ◽  
Author(s):  
Seyed Mohammad Taghdisi ◽  
Noor Mohammad Danesh ◽  
Parirokh Lavaee ◽  
Ahmad Sarreshtehdar Emrani ◽  
Mohammad Ramezani ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Gold Nanoparticles ◽  
Triple Helix ◽  
Molecular Switch ◽  
Environmental Contaminant ◽  
Ultrasensitive Detection ◽  
Toxic Heavy Metals

Lead (Pb) is a serious environmental contaminant and one of the most toxic heavy metals.

A sensitive colorimetric aptasensor with a triple-helix molecular switch based on peroxidase-like activity of a DNAzyme for ATP detection

2017 ◽  
Vol 9 (32) ◽  
pp. 4726-4731 ◽  
Author(s):  
Kosar Shahsavar ◽  
Morteza Hosseini ◽  
Ehsan Shokri ◽  
Mohammad Reza Ganjali ◽  
Huangxian Ju
Keyword(s):  
Adenosine Triphosphate ◽  
Triple Helix ◽  
Molecular Switch ◽  
Colorimetric Aptasensor ◽  
Atp Detection

A DNAzyme-based colorimetric aptasensor has been fabricated for fast readout and facile detection of adenosine triphosphate (ATP).

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