Triple-helix molecular-switch-actuated exponential rolling circular amplification for ultrasensitive fluorescence detection of miRNAs

The Analyst ◽  
2019 ◽  
Vol 144 (17) ◽  
pp. 5245-5253 ◽  
Author(s):  
Yihan Zhao ◽  
Yu Wang ◽  
Su Liu ◽  
Chonglin Wang ◽  
Jiaxu Liang ◽  
...  
Keyword(s):  
Fluorescence Detection ◽  
Triple Helix ◽  
High Efficiency ◽  
Molecular Switch ◽  
Ultrasensitive Detection ◽  
Fluorescent Biosensing

We have developed a rapid and high-efficiency fluorescent biosensing platform based on triple-helix molecular-switch (THMS)-actuated exponential rolling circular amplification (RCA) strategy for the ultrasensitive detection of miR-21.

Triple-Helix Molecular Switch Electrochemical Ratiometric Biosensor for Ultrasensitive Detection of Nucleic Acids

2017 ◽  
Vol 89 (17) ◽  
pp. 8830-8835 ◽  
Author(s):  
Erhu Xiong ◽  
Zhenzhen Li ◽  
Xiaohua Zhang ◽  
Jiawan Zhou ◽  
Xiaoxia Yan ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Triple Helix ◽  
Molecular Switch ◽  
Ultrasensitive Detection

A novel colorimetric triple-helix molecular switch aptasensor based on peroxidase-like activity of gold nanoparticles for ultrasensitive detection of lead(ii)

RSC Advances ◽  
2015 ◽  
Vol 5 (54) ◽  
pp. 43508-43514 ◽  
Author(s):  
Seyed Mohammad Taghdisi ◽  
Noor Mohammad Danesh ◽  
Parirokh Lavaee ◽  
Ahmad Sarreshtehdar Emrani ◽  
Mohammad Ramezani ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Gold Nanoparticles ◽  
Triple Helix ◽  
Molecular Switch ◽  
Environmental Contaminant ◽  
Ultrasensitive Detection ◽  
Toxic Heavy Metals

Lead (Pb) is a serious environmental contaminant and one of the most toxic heavy metals.

A novel colorimetric triple-helix molecular switch aptasensor for ultrasensitive detection of tetracycline

2015 ◽  
Vol 70 ◽  
pp. 181-187 ◽  
Author(s):  
Mohammad Ramezani ◽  
Noor Mohammad Danesh ◽  
Parirokh Lavaee ◽  
Khalil Abnous ◽  
Seyed Mohammad Taghdisi
Keyword(s):  
Triple Helix ◽  
Molecular Switch ◽  
Ultrasensitive Detection

A sensitive SERS assay for detecting proteins and nucleic acids using a triple-helix molecular switch for cascade signal amplification

2014 ◽  
Vol 50 (66) ◽  
pp. 9409-9412 ◽  
Author(s):  
Sujuan Ye ◽  
Yanying Wu ◽  
Wen Zhang ◽  
Na Li ◽  
Bo Tang
Keyword(s):  
Nucleic Acids ◽  
Signal Amplification ◽  
Triple Helix ◽  
Detection System ◽  
Molecular Switch ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Multiple Cycle ◽  
Enhanced Raman Scattering

A sensitive surface-enhanced Raman scattering (SERS) detection system is developed for proteins and nucleic acids based on a triple-helix molecular switch for multiple cycle signal amplification.

High-Efficiency Triple-Helix-Mediated Photo-Cross-Linking at a Targeted Site within a Selectable Mammalian Gene†

Biochemistry ◽  
1996 ◽  
Vol 35 (33) ◽  
pp. 10712-10719 ◽  
Author(s):  
Karen M. Vasquez ◽  
Theodore G. Wensel ◽  
Michael E. Hogan ◽  
John H. Wilson
Keyword(s):  
Triple Helix ◽  
High Efficiency ◽  
Cross Linking ◽  
Mammalian Gene

A versatile signal-on electrochemical biosensor for Staphylococcus aureus based on triple-helix molecular switch

2021 ◽  
Vol 326 ◽  
pp. 128842
Author(s):  
Rongfeng Cai ◽  
Zhongwen Zhang ◽  
Haohan Chen ◽  
Yaping Tian ◽  
Nandi Zhou
Keyword(s):  
Staphylococcus Aureus ◽  
Triple Helix ◽  
Electrochemical Biosensor ◽  
Molecular Switch

A triple-helix molecular switch photoelectrochemical biosensor for ultrasensitive microRNA detection based on position-controllable CdS//CdTe signal enhancement and switching

2020 ◽  
Vol 56 (19) ◽  
pp. 2909-2912 ◽  
Author(s):  
Wenchao Geng ◽  
Ruiying Yang
Keyword(s):  
Triple Helix ◽  
Molecular Switch ◽  
Signal Enhancement ◽  
Microrna Detection ◽  
Photoelectrochemical Biosensor

A triple-helix molecular switch photoelectrochemical biosensor is developed for ultrasensitive microRNA detection based on position-controllable CdS//CdTe signal enhancement and switching.

Ultrasensitive nuclease activity and inhibition assay using microchip electrophoresis with laser induced fluorescence detection

2016 ◽  
Vol 8 (8) ◽  
pp. 1852-1857 ◽  
Author(s):  
Yingfeng Qin ◽  
Jingjin Zhao ◽  
Yong Huang ◽  
Shuting Li ◽  
Shulin Zhao
Keyword(s):  
Fluorescence Detection ◽  
Nuclease Activity ◽  
Microchip Electrophoresis ◽  
Laser Induced Fluorescence ◽  
Ultrasensitive Detection ◽  
Inhibition Assay ◽  
Laser Induced Fluorescence Detection ◽  
Electrophoresis Method

A novel microchip electrophoresis method with laser induced fluorescence detection was developed for ultrasensitive detection of nuclease activity and inhibitors.

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