Conformer-Specific Hydrogen Exchange Analysis of Aβ(1–42) Oligomers by Top-Down Electron Capture Dissociation Mass Spectrometry

2011 ◽  
Vol 83 (13) ◽  
pp. 5386-5393 ◽  
Author(s):  
Jingxi Pan ◽  
Jun Han ◽  
Christoph H. Borchers ◽  
Lars Konermann
Keyword(s):  
Mass Spectrometry ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Hydrogen Exchange ◽  
Top Down

scholarly journals Electron capture dissociation and drift tube ion mobility-mass spectrometry coupled with site directed mutations provide insights into the conformational diversity of a metamorphic protein

2015 ◽  
Vol 17 (16) ◽  
pp. 10538-10550 ◽  
Author(s):  
Sophie R. Harvey ◽  
Massimiliano Porrini ◽  
Robert C. Tyler ◽  
Cait E. MacPhee ◽  
Brian F. Volkman ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Ion Mobility ◽  
Drift Tube ◽  
Ion Mobility Mass Spectrometry ◽  
Top Down ◽  
Conformational Diversity ◽  
Metamorphic Protein

Ion mobility mass spectrometry can be combined with data from top-down sequencing to discern adopted conformations of proteins in the absence of solvent.

scholarly journals Native Electrospray and Electron-Capture Dissociation FTICR Mass Spectrometry for Top-Down Studies of Protein Assemblies

2011 ◽  
Vol 83 (14) ◽  
pp. 5598-5606 ◽  
Author(s):  
Hao Zhang ◽  
Weidong Cui ◽  
Jianzhong Wen ◽  
Robert E. Blankenship ◽  
Michael L. Gross
Keyword(s):  
Mass Spectrometry ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Protein Assemblies ◽  
Top Down ◽  
Fticr Mass Spectrometry
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