Top-Down Structural Analysis of an Intact Monoclonal Antibody by Electron Capture Dissociation-Fourier Transform Ion Cyclotron Resonance-Mass Spectrometry

Yuan Mao; Santosh G. Valeja; Jason C. Rouse; Christopher L. Hendrickson; Alan G. Marshall

doi:10.1021/ac303525n

Top-Down Structural Analysis of an Intact Monoclonal Antibody by Electron Capture Dissociation-Fourier Transform Ion Cyclotron Resonance-Mass Spectrometry

Analytical Chemistry ◽

10.1021/ac303525n ◽

2013 ◽

Vol 85 (9) ◽

pp. 4239-4246 ◽

Cited By ~ 78

Author(s):

Yuan Mao ◽

Santosh G. Valeja ◽

Jason C. Rouse ◽

Christopher L. Hendrickson ◽

Alan G. Marshall

Keyword(s):

Mass Spectrometry ◽

Monoclonal Antibody ◽

Fourier Transform ◽

Structural Analysis ◽

Electron Capture ◽

Electron Capture Dissociation ◽

Cyclotron Resonance ◽

Ion Cyclotron Resonance ◽

Top Down ◽

Ion Cyclotron

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Faculty Opinions recommendation of Top-down structural analysis of posttranslationally modified proteins by Fourier transform ion cyclotron resonance-MS with hydrogen/deuterium exchange and electron capture dissociation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717973380.793470081 ◽

2013 ◽

Author(s):

Patricia C Weber

Keyword(s):

Fourier Transform ◽

Structural Analysis ◽

Electron Capture ◽

Electron Capture Dissociation ◽

Cyclotron Resonance ◽

Ion Cyclotron Resonance ◽

Hydrogen Deuterium Exchange ◽

Top Down ◽

Hydrogen Deuterium ◽

Modified Proteins

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Electron Capture Dissociation Implementation Progress in Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Journal of the American Society for Mass Spectrometry ◽

10.1016/j.jasms.2008.02.007 ◽

2008 ◽

Vol 19 (6) ◽

pp. 762-771 ◽

Cited By ~ 27

Author(s):

Yury O. Tsybin ◽

John P. Quinn ◽

Oleg Yu Tsybin ◽

Christopher L. Hendrickson ◽

Alan G. Marshall

Keyword(s):

Mass Spectrometry ◽

Fourier Transform ◽

Electron Capture ◽

Electron Capture Dissociation ◽

Cyclotron Resonance ◽

Ion Cyclotron Resonance ◽

Ion Cyclotron ◽

Implementation Progress

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Structural Analysis of an Intact Monoclonal Antibody by Online Electrochemical Reduction of Disulfide Bonds and Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Analytical Chemistry ◽

10.1021/ac500383c ◽

2014 ◽

Vol 86 (11) ◽

pp. 5376-5382 ◽

Cited By ~ 40

Author(s):

Simone Nicolardi ◽

André M. Deelder ◽

Magnus Palmblad ◽

Yuri E. M. van der Burgt

Keyword(s):

Mass Spectrometry ◽

Monoclonal Antibody ◽

Fourier Transform ◽

Structural Analysis ◽

Electrochemical Reduction ◽

Cyclotron Resonance ◽

Disulfide Bonds ◽

Ion Cyclotron Resonance ◽

Ion Cyclotron

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Determination of AberrantO-Glycosylation in the IgA1 Hinge Region by Electron Capture Dissociation Fourier Transform-Ion Cyclotron Resonance Mass Spectrometry

Journal of Biological Chemistry ◽

10.1074/jbc.m411368200 ◽

2005 ◽

Vol 280 (19) ◽

pp. 19136-19145 ◽

Cited By ~ 99

Author(s):

Matthew B. Renfrow ◽

Helen J. Cooper ◽

Milan Tomana ◽

Rose Kulhavy ◽

Yoshiyuki Hiki ◽

...

Keyword(s):

Mass Spectrometry ◽

Fourier Transform ◽

Electron Capture ◽

Electron Capture Dissociation ◽

Cyclotron Resonance ◽

Hinge Region ◽

Ion Cyclotron Resonance ◽

Ion Cyclotron

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Evaluation and optimization of electron capture dissociation efficiency in fourier transform ion cyclotron resonance mass spectrometry

Journal of the American Society for Mass Spectrometry ◽

10.1016/j.jasms.2005.03.020 ◽

2005 ◽

Vol 16 (7) ◽

pp. 1060-1066 ◽

Cited By ~ 23

Author(s):

Melinda A. McFarland ◽

Michael J. Chalmers ◽

John P. Quinn ◽

Christopher L. Hendrickson ◽

Alan G. Marshall

Keyword(s):

Mass Spectrometry ◽

Fourier Transform ◽

Electron Capture ◽

Electron Capture Dissociation ◽

Cyclotron Resonance ◽

Ion Cyclotron Resonance ◽

Dissociation Efficiency ◽

Ion Cyclotron

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Peptide and protein characterization by high-rate electron capture dissociation Fourier transform ion cyclotron resonance mass spectrometry

Journal of Mass Spectrometry ◽

10.1002/jms.658 ◽

2004 ◽

Vol 39 (7) ◽

pp. 719-729 ◽

Cited By ~ 31

Author(s):

Youri O. Tsybin ◽

Margareta Ramström ◽

Matthias Witt ◽

Gökhan Baykut ◽

Per Håkansson

Keyword(s):

Mass Spectrometry ◽

Fourier Transform ◽

Electron Capture ◽

Electron Capture Dissociation ◽

Cyclotron Resonance ◽

Protein Characterization ◽

High Rate ◽

Ion Cyclotron Resonance ◽

Ion Cyclotron

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Combined infrared multiphoton dissociation and electron-capture dissociation using co-linear and overlapping beams in Fourier transform ion cyclotron resonance mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.2520 ◽

2006 ◽

Vol 20 (12) ◽

pp. 1838-1844 ◽

Cited By ~ 18

Author(s):

Romulus Mihalca ◽

Yuri E. M. van der Burgt ◽

Liam A. McDonnell ◽

Marc Duursma ◽

Iliya Cerjak ◽

...

Keyword(s):

Mass Spectrometry ◽

Fourier Transform ◽

Electron Capture ◽

Electron Capture Dissociation ◽

Cyclotron Resonance ◽

Infrared Multiphoton Dissociation ◽

Ion Cyclotron Resonance ◽

Ion Cyclotron ◽

Multiphoton Dissociation

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Erratum to: An antibiotic linked to peptides and proteins is released by electron capture dissociation fourier transform ion cyclotron resonance mass spectrometry

Journal of the American Society for Mass Spectrometry ◽

10.1016/s1044-0305(03)00331-3 ◽

2003 ◽

Vol 14 (6) ◽

pp. 682-682 ◽

Cited By ~ 1

Author(s):

Clifton K. Fagerquist ◽

Robert R. Hudgins ◽

Mark R. Emmett ◽

Kristina Håkansson ◽

Alan G. Marshall

Keyword(s):

Mass Spectrometry ◽

Fourier Transform ◽

Electron Capture ◽

Electron Capture Dissociation ◽

Cyclotron Resonance ◽

Ion Cyclotron Resonance ◽

Ion Cyclotron

Download Full-text

Peptide and protein characterization by high-rate electron capture dissociation Fourier transform ion cyclotron resonance mass spectrometry. J. Mass Spectrom. 2004;39(7): 719–729

Journal of Mass Spectrometry ◽

10.1002/jms.692 ◽

2004 ◽

Vol 39 (9) ◽

pp. 1077-1077 ◽

Cited By ~ 1

Author(s):

Youri O. Tsybin ◽

Margareta Ramström ◽

Matthias Witt ◽

Gökhan Baykut ◽

Per Håkansson

Keyword(s):

Mass Spectrometry ◽

Fourier Transform ◽

Electron Capture ◽

Electron Capture Dissociation ◽

Cyclotron Resonance ◽

Protein Characterization ◽

High Rate ◽

Ion Cyclotron Resonance ◽

Mass Spectrom ◽

Ion Cyclotron

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Top-down structural analysis of posttranslationally modified proteins by Fourier transform ion cyclotron resonance-MS with hydrogen/deuterium exchange and electron capture dissociation

PROTEOMICS ◽

10.1002/pmic.201200246 ◽

2013 ◽

Vol 13 (6) ◽

pp. 974-981 ◽

Cited By ~ 30

Author(s):

Jingxi Pan ◽

Christoph H. Borchers

Keyword(s):

Fourier Transform ◽

Structural Analysis ◽

Electron Capture ◽

Electron Capture Dissociation ◽

Cyclotron Resonance ◽

Ion Cyclotron Resonance ◽

Hydrogen Deuterium Exchange ◽

Top Down ◽

Hydrogen Deuterium ◽

Modified Proteins

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