Reproducibility and Robustness of a Real-Time Microfluidic Cell Toxicity Assay

2011 ◽  
Vol 83 (10) ◽  
pp. 3890-3896 ◽  
Author(s):  
Gregory A. Cooksey ◽  
John T. Elliott ◽  
Anne L. Plant
Keyword(s):  
Real Time ◽  
Cell Toxicity ◽  
Toxicity Assay

scholarly journals Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage

PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0177902 ◽  
Author(s):  
Jui-Hua Hsieh ◽  
Ruili Huang ◽  
Ja-An Lin ◽  
Alexander Sedykh ◽  
Jinghua Zhao ◽  
...  
Keyword(s):  
Real Time ◽  
Cell Toxicity ◽  
Toxicity Pathway

scholarly journals A spheroid toxicity assay using magnetic 3D bioprinting and real-time mobile device-based imaging

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Hubert Tseng ◽  
Jacob A. Gage ◽  
Tsaiwei Shen ◽  
William L. Haisler ◽  
Shane K. Neeley ◽  
...  
Keyword(s):  
Real Time ◽  
Mobile Device ◽  
3D Bioprinting ◽  
Toxicity Assay

Single identical cell toxicity assay on coordinately ordered patterns

2019 ◽  
Vol 1065 ◽  
pp. 56-63 ◽  
Author(s):  
Qingxuan Li ◽  
Liyuan Ma ◽  
Ming Su
Keyword(s):  
Cell Toxicity ◽  
Toxicity Assay ◽  
Identical Cell

scholarly journals Correction: Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage

PLoS ONE ◽  
2017 ◽  
Vol 12 (7) ◽  
pp. e0181291 ◽  
Author(s):  
Jui-Hua Hsieh ◽  
Ruili Huang ◽  
Ja-An Lin ◽  
Alexander Sedykh ◽  
Jinghua Zhao ◽  
...  
Keyword(s):  
Real Time ◽  
Cell Toxicity ◽  
Toxicity Pathway

Novel Primary Epithelial Cell Toxicity Assay Using Porcine Corneal Explants

Cornea ◽  
2015 ◽  
Vol 34 (5) ◽  
pp. 567-575 ◽  
Author(s):  
Hiroki Takahashi ◽  
Kazuki Tajima ◽  
Takaaki Hattori ◽  
Naoyuki Yamakawa ◽  
Norihiko Ito ◽  
...  
Keyword(s):  
Epithelial Cell ◽  
Cell Toxicity ◽  
Toxicity Assay ◽  
Primary Epithelial Cell

scholarly journals Inhibition of the filamentation of Candida albicans by Borojoa patinoi silver nanoparticles

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Marcela Gómez-Garzón ◽  
Luz D. Gutiérrez-Castañeda ◽  
Camilo Gil ◽  
Carlos H. Escobar ◽  
Ana P. Rozo ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Candida Albicans ◽  
Green Synthesis ◽  
Cell Line ◽  
Opportunistic Pathogen ◽  
Inhibitory Effect ◽  
Cell Toxicity ◽  
Toxicity Assay ◽  
Filamentous Form ◽  
Shape And Size

AbstractCandida albicans is fungus capable of changing from yeast to filamentous form when it’s transformed from a normal commensal to an opportunistic pathogen. The development of alternatives that interfere with this transition could be an effective way to reduce candidiasis. In this regard, evaluate the inhibitory effect of two Borojoa patinoi silver nanoparticles (AgNPs) produced by green synthesis at 5 °C and 25 °C on the process of filamentation of Candida albicans. The percentage of inhibition of filamentous forms of C. albicans ATCC10231 and C. albicans SC5314 with AgNPs was determined. Results showed that temperature of synthesis affected both the shape and size of silver nanoparticles synthesized using Borojoa patinoi extracts. The inhibition percentage of filamentous forms of Candida albicans ATCC10231 when treated with silver nanoparticles synthesized at 5 °C was 85.9% and at 25 °C it was 40%. C. albicans SC5314 when treated with AgNP synthesized at 5 °C was 97.2% and at 25 °C it was 64%. Cell toxicity assay showed that at 100ng/ml, AgNPs synthesized at 25 °C were safe in MES-OV CRL-3272 cell line. Our results showed that the silver nanoparticles obtained from Borojoa patinoi are inhibitors of the filamentous process of C. albicans.

Interdependence of initial cell density, drug concentration and exposure time revealed by real-time impedance spectroscopic cytotoxicity assay

The Analyst ◽  
2015 ◽  
Vol 140 (10) ◽  
pp. 3623-3629 ◽  
Author(s):  
C. Caviglia ◽  
K. Zór ◽  
S. Canepa ◽  
M. Carminati ◽  
L. B. Larsen ◽  
...  
Keyword(s):  
Real Time ◽  
Cell Density ◽  
Exposure Time ◽  
Drug Concentration ◽  
Drug Toxicity ◽  
Drug Exposure ◽  
Cytotoxicity Assay ◽  
Toxicity Assay ◽  
Initial Cell ◽  
Initial Cell Density

The impedance-based drug toxicity assay reveals the effect of cancer drugs, showing the interdependence of the drug exposure time, concentration, and cell density.

scholarly journals Development of a highly sensitive in vitro endothelial cell toxicity assay for evaluating ricin toxin A chain-based vaccines or therapeutics

Toxicon ◽  
2019 ◽  
Vol 167 ◽  
pp. 152-161 ◽  
Author(s):  
Nicholas J. Machesky ◽  
Janice M. Rusnak ◽  
Evan H. Moore ◽  
Christopher B. Dorsey ◽  
Lucy A. Ward
Keyword(s):  
Endothelial Cell ◽  
Cell Toxicity ◽  
Toxin A ◽  
Toxicity Assay ◽  
Ricin Toxin ◽  
Highly Sensitive ◽  
A Chain
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