scholarly journals Characterization of Local pH Changes in Brain Using Fast-Scan Cyclic Voltammetry with Carbon Microelectrodes

2010 ◽  
Vol 82 (23) ◽  
pp. 9892-9900 ◽  
Author(s):  
Pavel Takmakov ◽  
Matthew K. Zachek ◽  
Richard B. Keithley ◽  
Elizabeth S. Bucher ◽  
Gregory S. McCarty ◽  
...  
Keyword(s):  
Cyclic Voltammetry ◽  
Fast Scan Cyclic Voltammetry ◽  
Ph Changes ◽  
Local Ph

Characterization of rates of adsorption with fast-scan cyclic voltammetry

1989 ◽  
Vol 265 (1-2) ◽  
pp. 291-296 ◽  
Author(s):  
Jonathan A. Stamford ◽  
Peter R. Hurst ◽  
Wemer G. Kuhr ◽  
R.Mark Wightman
Keyword(s):  
Cyclic Voltammetry ◽  
Fast Scan Cyclic Voltammetry

Characterization of Electroactive Amino Acids with Fast-Scan Cyclic Voltammetry

2021 ◽  
Author(s):  
Moriah E Weese-Myers ◽  
Ashley E Ross
Keyword(s):  
Amino Acids ◽  
Cyclic Voltammetry ◽  
Electrochemical Technique ◽  
Fast Scan Cyclic Voltammetry ◽  
Design And Optimization ◽  
Peptide Release ◽  
Signaling Peptides ◽  
The Brain

Abstract Small molecules and signaling peptides are extensively involved in controlling basic brain function. While classical neurotransmitters can be detected with a variety of techniques, methods for measurement of rapidly-released neuropeptides remain underdeveloped. Fast-scan cyclic voltammetry (FSCV) is an electrochemical technique often used for subsecond detection of small molecule neurotransmitters, in vivo. A few peptides have been detected with FSCV; however, a detailed analysis of the electrochemical signature of all electroactive amino acids with FSCV has not been fully investigated. Because the mechanisms, locations, and timescales for signaling peptide release in the brain are relatively unexplored, developing sensitive and selective tools capable of quantitating neuropeptide signaling is essential. To bridge this gap, we used FSCV to characterize the electroactive amino acids: cysteine, methionine, histidine, tryptophan, and tyrosine. We show that tyrosine, tryptophan, and histidine are easily oxidized on carbon fiber surfaces with FSCV, while detection of the sulfur-containing amino acids is more difficult. This study provides critical information for electrochemical waveform design and optimization for detection of peptides containing these amino acids.

Application of fast-scan cyclic voltammetry for the in vivo characterization of optically evoked dopamine in the olfactory tubercle of the rat brain

The Analyst ◽  
2016 ◽  
Vol 141 (12) ◽  
pp. 3746-3755 ◽  
Author(s):  
Ken T. Wakabayashi ◽  
Michael J. Bruno ◽  
Caroline E. Bass ◽  
Jinwoo Park
Keyword(s):  
Cyclic Voltammetry ◽  
Carbon Fiber ◽  
Rat Brain ◽  
Olfactory Tubercle ◽  
Fast Scan Cyclic Voltammetry ◽  
Carbon Fiber Microelectrodes ◽  
In Vivo Characterization

Dopamine regulation in the rat brain olfactory tubercle was characterized by fast-scan cyclic voltammetry coupled with carbon–fiber microelectrodes and optogenetics.

Subsecond detection of guanosine using fast-scan cyclic voltammetry

The Analyst ◽  
2019 ◽  
Vol 144 (1) ◽  
pp. 249-257 ◽  
Author(s):  
Michael T. Cryan ◽  
Ashley E. Ross
Keyword(s):  
Cyclic Voltammetry ◽  
Carbon Fiber ◽  
Electrochemical Characterization ◽  
Fast Scan Cyclic Voltammetry ◽  
Carbon Fiber Microelectrodes

We present the first electrochemical characterization of guanosine, a purinergic neuromodulator and neuroprotector, using fast-scan cyclic voltammetry at carbon-fiber microelectrodes.

scholarly journals Use of Amperometric and Potentiometric Probes in Scanning Electrochemical Microscopy for the Spatially-Resolved Monitoring of Severe Localized Corrosion Sites on Aluminum Alloy 2098-T351

Sensors ◽  
2021 ◽  
Vol 21 (4) ◽  
pp. 1132 ◽  
Author(s):  
Rejane M. P. da Silva ◽  
Javier Izquierdo ◽  
Mariana X. Milagre ◽  
Abenchara M. Betancor-Abreu ◽  
Isolda Costa ◽  
...  
Keyword(s):  
Scanning Electrochemical Microscopy ◽  
Oxygen Depletion ◽  
Localized Corrosion ◽  
Alloy Surface ◽  
Al Alloy ◽  
Spatially Resolved ◽  
Lower Oxygen ◽  
Local Ph ◽  
Electrochemical Microscopy

Amperometric and potentiometric probes were employed for the detection and characterization of reactive sites on the 2098-T351 Al-alloy (AA2098-T351) using scanning electrochemical microscopy (SECM). Firstly, the probe of concept was performed on a model Mg-Al galvanic pair system using SECM in the amperometric and potentiometric operation modes, in order to address the responsiveness of the probes for the characterization of this galvanic pair system. Next, these sensing probes were employed to characterize the 2098-T351 alloy surface immersed in a saline aqueous solution at ambient temperature. The distribution of reactive sites and the local pH changes associated with severe localized corrosion (SLC) on the alloy surface were imaged and subsequently studied. Higher hydrogen evolution, lower oxygen depletion and acidification occurred at the SLC sites developed on the 2098-T351 Al-alloy.

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