Parallel G-Quadruplex-Specific Fluorescent Probe for Monitoring DNA Structural Changes and Label-Free Detection of Potassium Ion

2010 ◽  
Vol 82 (18) ◽  
pp. 7576-7580 ◽  
Author(s):  
Tao Li ◽  
Erkang Wang ◽  
Shaojun Dong
Keyword(s):  
Fluorescent Probe ◽  
Structural Changes ◽  
Potassium Ion ◽  
Label Free ◽  
Label Free Detection ◽  
G Quadruplex

Label-free detection of folic acid using a sensitive fluorescent probe based on ovalbumin stabilized copper nanoclusters

Talanta ◽  
2019 ◽  
Vol 195 ◽  
pp. 372-380 ◽  
Author(s):  
Xinge Li ◽  
Xiaoman Wu ◽  
Fei Zhang ◽  
Bing Zhao ◽  
Yan Li
Keyword(s):  
Folic Acid ◽  
Fluorescent Probe ◽  
Label Free ◽  
Copper Nanoclusters ◽  
Label Free Detection

scholarly journals Comparison of DNAzyme activity for the development of an immobilized heme sensor

MRS Advances ◽  
2018 ◽  
Vol 3 (26) ◽  
pp. 1491-1496
Author(s):  
Natalie Hughes ◽  
Nancy Nguyen ◽  
Deanna-Kaye Daley ◽  
Justin Grennell ◽  
Amira Gee ◽  
...  
Keyword(s):  
Self Assembly ◽  
Point Of Care ◽  
Label Free ◽  
Detection Range ◽  
Chemical Complexity ◽  
Detection Strategy ◽  
Detection Approach ◽  
Label Free Detection ◽  
G Quadruplex ◽  
Care Systems

ABSTRACTPoint-of-care systems require highly sensitive, quantitative and selective detection platforms for the real-time multiplexed monitoring of target analytes. To ensure facile development of a sensor, it is preferable for the detection assay to have minimal chemical complexity, contain no wash steps and provide a wide and easily adaptable detection range for multiple targets. Current studies involve label-free detection strategy for relevant clinical molecules such as heme using G-quadruplex based self-assembly. We have explored the measurement of binding and kinetic parameters of various G-quadruplex/heme complexes which are able to self-associate to form a DNAzyme with peroxidase mimicking capabilities and are critical to nucleic acid research. The detection strategy includes immobilizing the G-quadruplex sequences within a polymer matrix to provide a self-assembly based detection approach for heme that could be translated towards other clinically relevant targets.

scholarly journals Label Free Detection of Adenosine Based on Hemin/G-Quadruplex Peroxidase-Mimicking DNAzyme as Bioelectrocatalyst

2013 ◽  
Vol 25 (18) ◽  
pp. 10541-10545 ◽  
Author(s):  
Yu Li ◽  
Sen Li ◽  
Ge-Qing Xia ◽  
Yuansheng Wang
Keyword(s):  
Label Free ◽  
Label Free Detection ◽  
G Quadruplex

Cationic-perylene-G-quadruplex complex based fluorescent biosensor for label-free detection of Pb 2+

Talanta ◽  
2016 ◽  
Vol 149 ◽  
pp. 98-102 ◽  
Author(s):  
Xu-Hua Zhao ◽  
Liang Gong ◽  
Yuan Wu ◽  
Xiao-Bing Zhang ◽  
Jun Xie
Keyword(s):  
Label Free ◽  
Fluorescent Biosensor ◽  
Label Free Detection ◽  
G Quadruplex

scholarly journals Label-free Detection of Zn2+ Based on G-quadruplex

2015 ◽  
Vol 31 (10) ◽  
pp. 1041-1045 ◽  
Author(s):  
Yahui GUO ◽  
Yan SUN ◽  
Xiaoqiang SHEN ◽  
Kunchi ZHANG ◽  
Jiming HU ◽  
...  
Keyword(s):  
Label Free ◽  
Label Free Detection ◽  
G Quadruplex
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