In Vivo Monitoring of Multiple Trace Metals in the Brain Extracellular Fluid of Anesthetized Rats by Microdialysis−Membrane Desalter−ICPMS

2007 ◽  
Vol 79 (23) ◽  
pp. 8900-8910 ◽  
Author(s):  
Y. T. Chung ◽  
Y. C. Ling ◽  
C. S. Yang ◽  
Y. C. Sun ◽  
P. L. Lee ◽  
...  
2002 ◽  
Vol 48 (3) ◽  
pp. 430-439 ◽  
Author(s):  
Jeffrey M. Macdonald ◽  
Olga Schmidlin ◽  
Thomas L. James

2000 ◽  
Vol 47 (1) ◽  
pp. 59-64
Author(s):  
T Kryczka ◽  
P Grieb ◽  
M Bero ◽  
J Kasperczyk ◽  
P Dobrzynski

We assessed the rate of release of a model nucleoside (adenosine, 5%, w/w) from nine different lactide-glycolide or lactide-caprolactone polymers. The polymer discs were eluted every second day with an artificial cerebrospinal fluid at the elution rate roughly approximating the brain extracellular fluid formation rate. Adenosine in eluate samples was assayed by HPLC. Three polymers exhibited a relatively constant release of adenosine for over four weeks, resulting in micromolar concentrations of nucleoside in the eluate. This points to the necessity of further development of polymers of this types as intracerebral nucleoside delivery systems for local treatment of brain tumors.


2012 ◽  
Vol 4 (2) ◽  
pp. 550 ◽  
Author(s):  
Niall J. Finnerty ◽  
Saidhbhe L. O'Riordan ◽  
Finbar O. Brown ◽  
Pier A. Serra ◽  
Robert D. O'Neill ◽  
...  

2006 ◽  
Vol 1118 (1) ◽  
pp. 34-42 ◽  
Author(s):  
W.H. Oldenziel ◽  
G. Dijkstra ◽  
T.I.F.H. Cremers ◽  
B.H.C. Westerink

2020 ◽  
Vol 524 (2) ◽  
pp. 340-345 ◽  
Author(s):  
Yuya Nishimura ◽  
Yota Fukuda ◽  
Toya Okonogi ◽  
Soichiro Yoshikawa ◽  
Hajime Karasuyama ◽  
...  

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