Internal Standard in Surface-Enhanced Raman Spectroscopy

2004 ◽  
Vol 76 (24) ◽  
pp. 7391-7395 ◽  
Author(s):  
A. Lorén ◽  
J. Engelbrektsson ◽  
C. Eliasson ◽  
M. Josefson ◽  
J. Abrahamsson ◽  
...  
2005 ◽  
Vol 77 (11) ◽  
pp. 3563-3569 ◽  
Author(s):  
Dongmao Zhang ◽  
Yong Xie ◽  
Shirshendu K. Deb ◽  
V. Jo Davison ◽  
Dor Ben-Amotz

2015 ◽  
Vol 7 (9) ◽  
pp. 3869-3875 ◽  
Author(s):  
Xiang Lin ◽  
Wu-Li-Ji Hasi ◽  
Xiu-Tao Lou ◽  
Si-qin-gao-wa Han ◽  
Dian-Yang Lin ◽  
...  

A SERS method has been developed to directly and quantitatively detect dicyandiamide in milk without any sample pretreatment through an internal standard method.


2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.


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