Development of a Methodology Based on Metal-Catalyzed Oxidation Reactions and Mass Spectrometry To Determine the Metal Binding Sites in Copper Metalloproteins

2003 ◽  
Vol 75 (5) ◽  
pp. 1164-1172 ◽  
Author(s):  
Jihyeon Lim ◽  
Richard W. Vachet
Keyword(s):  
Mass Spectrometry ◽  
Metal Binding ◽  
Binding Sites ◽  
Oxidation Reactions ◽  
Metal Binding Sites ◽  
Metal Catalyzed Oxidation ◽  
Metal Catalyzed ◽  
Catalyzed Oxidation

scholarly journals Mass Spectrometry-Based Structural Analysis of Cysteine-Rich Metal-Binding Sites in Proteins with MetaOdysseus R Software

2020 ◽  
Vol 20 (1) ◽  
pp. 776-785 ◽  
Author(s):  
Manuel David Peris-Díaz ◽  
Roman Guran ◽  
Ondrej Zitka ◽  
Vojtech Adam ◽  
Artur Krężel
Keyword(s):  
Mass Spectrometry ◽  
Structural Analysis ◽  
Metal Binding ◽  
Binding Sites ◽  
R Software ◽  
Metal Binding Sites

scholarly journals Metal-catalyzed oxidation of Aβ and the resulting reorganization of Cu binding sites promote ROS production

Metallomics ◽  
2016 ◽  
Vol 8 (10) ◽  
pp. 1081-1089 ◽  
Author(s):  
Clémence Cheignon ◽  
Peter Faller ◽  
Denis Testemale ◽  
Christelle Hureau ◽  
Fabrice Collin
Keyword(s):  
Binding Sites ◽  
The Self ◽  
Ros Production ◽  
Copper Coordination ◽  
Metal Catalyzed Oxidation ◽  
Metal Catalyzed ◽  
Catalyzed Oxidation

Aβ oxidation due to HO˙ production by Cu–Aβ/ascorbate changes copper coordination and leads to the self-enhancement of HO˙ production and release.

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