A Surface Acoustic Wave Biosensor Concept with Low Flow Cell Volumes for Label-Free Detection

2003 ◽  
Vol 75 (20) ◽  
pp. 5561-5566 ◽  
Author(s):  
Kerstin Länge ◽  
Florian Bender ◽  
Achim Voigt ◽  
Hui Gao ◽  
Michael Rapp
Keyword(s):  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Flow Cell ◽  
Low Flow ◽  
Label Free ◽  
Label Free Detection ◽  
Acoustic Wave Biosensor ◽  
Cell Volumes

Tailoring odorant-binding protein coatings characteristics for surface acoustic wave biosensor development

2014 ◽  
Vol 302 ◽  
pp. 250-255 ◽  
Author(s):  
F. Di Pietrantonio ◽  
M. Benetti ◽  
V. Dinca ◽  
D. Cannatà ◽  
E. Verona ◽  
...  
Keyword(s):  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Binding Protein ◽  
Odorant Binding Protein ◽  
Protein Coatings ◽  
Acoustic Wave Biosensor ◽  
Odorant Binding

scholarly journals Wave number–spiral acoustic tweezers for dynamic and reconfigurable manipulation of particles and cells

2019 ◽  
Vol 5 (5) ◽  
pp. eaau6062 ◽  
Author(s):  
Zhenhua Tian ◽  
Shujie Yang ◽  
Po-Hsun Huang ◽  
Zeyu Wang ◽  
Peiran Zhang ◽  
...  
Keyword(s):  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Cell Interaction ◽  
Cell Manipulation ◽  
Wave Number ◽  
Label Free ◽  
Multiple Functions ◽  
Pressure Distributions ◽  
Acoustic Tweezers ◽  
Interaction Research

Acoustic tweezers have recently raised great interest across many fields including biology, chemistry, engineering, and medicine, as they can perform contactless, label-free, biocompatible, and precise manipulation of particles and cells. Here, we present wave number–spiral acoustic tweezers, which are capable of dynamically reshaping surface acoustic wave (SAW) wavefields to various pressure distributions to facilitate dynamic and programmable particle/cell manipulation. SAWs propagating in multiple directions can be simultaneously and independently controlled by simply modulating the multitone excitation signals. This allows for dynamic reshaping of SAW wavefields to desired distributions, thus achieving programmable particle/cell manipulation. We experimentally demonstrated the multiple functions of wave number–spiral acoustic tweezers, among which are multiconfiguration patterning; parallel merging; pattern translation, transformation, and rotation; and dynamic translation of single microparticles along complex paths. This wave number–spiral design has the potential to revolutionize future acoustic tweezers development and advance many applications, including microscale assembly, bioprinting, and cell-cell interaction research.

scholarly journals Hybrid Sensor Device for Simultaneous Surface Plasmon Resonance and Surface Acoustic Wave Measurements

Sensors ◽  
2020 ◽  
Vol 20 (21) ◽  
pp. 6177
Author(s):  
Anastasios G. Samarentsis ◽  
Alexandros K. Pantazis ◽  
Achilleas Tsortos ◽  
Jean-Michel Friedt ◽  
Electra Gizeli
Keyword(s):  
Surface Plasmon Resonance ◽  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Love Wave ◽  
Future Application ◽  
Label Free ◽  
Combined System ◽  
Wave Measurements

Surface plasmon resonance (SPR) and Love wave (LW) surface acoustic wave (SAW) sensors have been established as reliable biosensing technologies for label-free, real-time monitoring of biomolecular interactions. This work reports the development of a combined SPR/LW-SAW platform to facilitate simultaneous optical and acoustic measurements for the investigation of biomolecules binding on a single surface. The system’s output provides recordings of two acoustic parameters, phase and amplitude of a Love wave, synchronized with SPR readings. We present the design and manufacturing of a novel experimental set-up employing, in addition to the SPR/LW-SAW device, a 3D-printed plastic holder combined with a PDMS microfluidic cell so that the platform can be used in a flow-through mode. The system was evaluated in a systematic study of the optical and acoustic responses for different surface perturbations, i.e., rigid mass loading (Au deposition), pure viscous loading (glycerol and sucrose solutions) and protein adsorption (BSA). Our results provide the theoretical and experimental basis for future application of the combined system to other biochemical and biophysical studies.

Detection of viral bioagents using a shear horizontal surface acoustic wave biosensor

2008 ◽  
Vol 23 (9) ◽  
pp. 1397-1403 ◽  
Author(s):  
M. Bisoffi ◽  
B. Hjelle ◽  
D.C. Brown ◽  
D.W. Branch ◽  
T.L. Edwards ◽  
...  
Keyword(s):  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Horizontal Surface ◽  
Acoustic Wave Biosensor ◽  
Shear Horizontal

Label-free detection of HIV-2 antibodies in serum with an ultra-high frequency acoustic wave sensor

Talanta ◽  
2011 ◽  
Vol 85 (1) ◽  
pp. 816-819 ◽  
Author(s):  
Sonia Sheikh ◽  
Christophe Blaszykowski ◽  
Michael Thompson
Keyword(s):  
Acoustic Wave ◽  
High Frequency ◽  
Label Free ◽  
Ultra High Frequency ◽  
Label Free Detection ◽  
Acoustic Wave Sensor
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