Layer-By-Layer Self-Assembly of Glucose Oxidase and Os(Bpy)2ClPyCH2NH−poly(Allylamine) Bioelectrode

2001 ◽  
Vol 73 (6) ◽  
pp. 1161-1168 ◽  
Author(s):  
E. J. Calvo ◽  
R. Etchenique ◽  
L. Pietrasanta ◽  
A. Wolosiuk ◽  
C. Danilowicz
2006 ◽  
Vol 41 (10) ◽  
pp. 3147-3149 ◽  
Author(s):  
Xin Hua Xu ◽  
Guang Lei Ren ◽  
Juan Cheng ◽  
Qiang Liu ◽  
Dong Guang Li ◽  
...  

Langmuir ◽  
1997 ◽  
Vol 13 (10) ◽  
pp. 2708-2716 ◽  
Author(s):  
Jose Hodak ◽  
Roberto Etchenique ◽  
Ernesto J. Calvo ◽  
Kavita Singhal ◽  
Philip N. Bartlett

2012 ◽  
Vol 160 (1) ◽  
pp. H6-H12 ◽  
Author(s):  
Lingyan Jin ◽  
Xia Gao ◽  
Huan Chen ◽  
Lisha Wang ◽  
Qi Wu ◽  
...  

Nanomaterials ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1884
Author(s):  
Mengfei Jin ◽  
Shangyong Li ◽  
Yanhong Wu ◽  
Dandan Li ◽  
Yantao Han

(1) Background: In the treatment of ulcerative colitis (UC), accurate delivery and release of anti-inflammatory drugs to the site of inflammation can reduce systemic side effects. (2) Methods: We took advantage of this goal to prepare resveratrol-loaded PLGA nanoparticles (RES-PCAC-NPs) by emulsification solvent volatilization. After layer-by-layer self-assembly technology, we deposited chitosan and alginate to form a three-layer polyelectrolyte film. (3) Results: It can transport nanoparticles through the gastric environment to target inflammation sites and slowly release drugs at a specific pH. The resulting RES-PCAC-NPs have an ideal average diameter (~255 nm), a narrow particle size distribution and a positively charged surface charge (~13.5 mV). The Fourier transform infrared spectroscopy showed that resveratrol was successfully encapsulated into PCAC nanoparticles, and the encapsulation efficiency reached 87.26%. In addition, fluorescence imaging showed that RES-PCAC-NPs with positive charges on the surface can effectively target and accumulate in the inflammation site while continuing to penetrate downward to promote mucosal healing. Importantly, oral RES-PCAC-NPs treatment in DSS-induced mice was superior to other results in significantly improved inflammatory markers of UC. (4) Conclusions: Our results strongly prove that RES-PCAC-NPs can target the inflamed colon for maximum efficacy, and this oral pharmaceutical formulation can represent a promising formulation in the treatment of UC.


2014 ◽  
Vol 14 (2) ◽  
pp. 1145-1153 ◽  
Author(s):  
Bing Yu ◽  
Xiaomian Liu ◽  
Hailin Cong ◽  
Hua Yuan ◽  
Dong Wang ◽  
...  
Keyword(s):  

2010 ◽  
Vol 46 (9) ◽  
pp. 1434 ◽  
Author(s):  
Meng Yang ◽  
Shanfu Lu ◽  
Jinlin Lu ◽  
San Ping Jiang ◽  
Yan Xiang

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