Performance Evaluation of an In-Injection Port Thermal Desorption/Gas Chromatographic/Negative Ion Chemical Ionization Mass Spectrometric Method for Trace Explosive Vapor Analysis

2001 ◽  
Vol 73 (4) ◽  
pp. 792-798 ◽  
Author(s):  
Michael E. Sigman ◽  
Cheng-Yu Ma ◽  
Ralph H. Ilgner
Keyword(s):  
Performance Evaluation ◽  
Chemical Ionization ◽  
Mass Spectrometric ◽  
Negative Ion ◽  
Spectrometric Method ◽  
Ionization Mass ◽  
Mass Spectrometric Method ◽  
Injection Port ◽  
Negative Ion Chemical Ionization ◽  
Vapor Analysis

Negative Ion Chemical Ionization Mass Spectrometric Method for Confirmation of Identity of Aflatoxin B,: Collaborative Study

1985 ◽  
Vol 68 (4) ◽  
pp. 636-640
Author(s):  
Douglas L Park ◽  
Vincent Diprossimo ◽  
Emil Abdel-Malek ◽  
Mary W Trucksess ◽  
Stanley Nesheim ◽  
...  
Keyword(s):  
Aflatoxin B1 ◽  
Chemical Ionization ◽  
Collaborative Study ◽  
The United States ◽  
Mass Spectrometric ◽  
West Germany ◽  
Negative Ion ◽  
Ionization Mass ◽  
Mass Spectrometric Method ◽  
Negative Ion Chemical Ionization

Abstract An interlaboratory study of a negative ion chemical ionization mass spectrometric (MS) confirmation procedure for aflatoxin B1 was conducted in laboratories in the United States, England, and West Germany. Twelve partially purified, dry film extracts from naturally and artificially contaminated roasted peanuts, cottonseed, and ginger root containing varying quantities of aflatoxin B1 were distributed to the participating laboratories. The extracts required additional cleanup before MS analysis, using either an acidic alumina column and preparative thin layer chromatography (TLC) or a 2-dimensional TLC procedure. Recovery of purified aflatoxin B1 was influenced by the degree of recovery of sample from acid alumina and/or the TLC plate and incomplete elution of aflatoxin Bt from silica gel. Factors affecting MS confirmation included the purity and recovery of aflatoxin and MS instrument sensitivity. Aflatoxin Bi identity was confirmed in 19.5, 90.9, and 100% of samples containing <5,5-10, and >10 ng aflatoxin B1/g product, respectively, by solid probe introduction using full mass scans. The MS method has been adopted official first action.

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