scholarly journals Body Mass Index and Depressive Symptoms: Testing for Adverse and Protective Associations in Two Twin Cohort Studies

2016 ◽  
Vol 19 (4) ◽  
pp. 306-311 ◽  
Author(s):  
Markus Jokela ◽  
Venla Berg ◽  
Karri Silventoinen ◽  
G. David Batty ◽  
Archana Singh-Manoux ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Depressive Symptoms ◽  
Cohort Studies ◽  
Body Mass ◽  
Genetic Model ◽  
The United States ◽  
Population Based ◽  
The Us ◽  
Mz Twins ◽  
Pair Analysis

Studies have suggested both adverse and protective associations of obesity with depressive symptoms. We examined the contribution of environmental and heritable factors in this association. Participants were same-sex twin pairs from two population-based twin cohort studies, the Older Finnish Twin Cohort (n = 8,215; mean age = 44.1) and the US Midlife Development in the United States (MIDUS; n = 1,105; mean age = 45.1). Body mass index (BMI) was calculated from self-reported height and weight. Depressive symptoms were assessed using Beck's Depression Inventory (BDI; Finnish Twin Cohort), and by negative and positive affect scales (MIDUS). In the Finnish Twin Cohort, higher BMI was associated with higher depressive symptoms in monozygotic (MZ) twins (B = 2.01, 95% CI = 1.0, 3.0) and dizygotic (DZ) twins (B = 1.17, 0.5, 1.9) with BMI >22. This association was observed in within-pair analysis in DZ twins (B = 1.47, CI = 0.4, 2.6) but not in within-pair analysis of MZ twins (B = 0.03, CI = -1.9, 2.0). Consistent with the latter result, a bivariate genetic model indicated that the association between higher BMI and higher depressive symptoms was largely mediated by genetic factors. The results of twin-pair analysis and bivariate genetic model were replicated in the MIDUS sample. These findings suggest an association between obesity and higher depressive symptoms, which is largely explained by shared heritable biological mechanisms.

scholarly journals Trends in obesity and adiposity measures by race or ethnicity among adults in the United States 2011-18: population based study

BMJ ◽  
2021 ◽  
pp. n365
Author(s):  
Buyun Liu ◽  
Yang Du ◽  
Yuxiao Wu ◽  
Linda G Snetselaar ◽  
Robert B Wallace ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Waist Circumference ◽  
Ethnic Groups ◽  
Body Mass ◽  
Body Fat ◽  
Lean Mass ◽  
The United States ◽  
Population Based ◽  
Body Fat Percentage ◽  
Fat Percentage

AbstractObjectiveTo examine the trends in obesity and adiposity measures, including body mass index, waist circumference, body fat percentage, and lean mass, by race or ethnicity among adults in the United States from 2011 to 2018.DesignPopulation based study.SettingNational Health and Nutrition Examination Survey (NHANES), 2011-18.ParticipantsA nationally representative sample of US adults aged 20 years or older.Main outcome measuresWeight, height, and waist circumference among adults aged 20 years or older were measured by trained technicians using standardized protocols. Obesity was defined as body mass index of 30 or higher for non-Asians and 27.5 or higher for Asians. Abdominal obesity was defined as a waist circumference of 102 cm or larger for men and 88 cm or larger for women. Body fat percentage and lean mass were measured among adults aged 20-59 years by using dual energy x ray absorptiometry.ResultsThis study included 21 399 adults from NHANES 2011-18. Body mass index was measured for 21 093 adults, waist circumference for 20 080 adults, and body fat percentage for 10 864 adults. For the overall population, age adjusted prevalence of general obesity increased from 35.4% (95% confidence interval 32.5% to 38.3%) in 2011-12 to 43.4% (39.8% to 47.0%) in 2017-18 (P for trend<0.001), and age adjusted prevalence of abdominal obesity increased from 54.5% (51.2% to 57.8%) in 2011-12 to 59.1% (55.6% to 62.7%) in 2017-18 (P for trend=0.02). Age adjusted mean body mass index increased from 28.7 (28.2 to 29.1) in 2011-12 to 29.8 (29.2 to 30.4) in 2017-18 (P for trend=0.001), and age adjusted mean waist circumference increased from 98.4 cm (97.4 to 99.5 cm) in 2011-12 to 100.5 cm (98.9 to 102.1 cm) in 2017-18 (P for trend=0.01). Significant increases were observed in body mass index and waist circumference among the Hispanic, non-Hispanic white, and non-Hispanic Asian groups (all P for trend<0.05), but not for the non-Hispanic black group. For body fat percentage, a significant increase was observed among non-Hispanic Asians (30.6%, 29.8% to 31.4% in 2011-12; 32.7%, 32.0% to 33.4% in 2017-18; P for trend=0.001), but not among other racial or ethnic groups. The age adjusted mean lean mass decreased in the non-Hispanic black group and increased in the non-Hispanic Asian group, but no statistically significant changes were found in other racial or ethnic groups.ConclusionsAmong US adults, an increasing trend was found in obesity and adiposity measures from 2011 to 2018, although disparities exist among racial or ethnic groups.

scholarly journals Body mass index and breast cancer risk in Japan: a pooled analysis of eight population-based cohort studies

2014 ◽  
Vol 25 (2) ◽  
pp. 519-524 ◽  
Author(s):  
K. Wada ◽  
C. Nagata ◽  
A. Tamakoshi ◽  
K. Matsuo ◽  
I. Oze ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Body Mass Index ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Cohort Studies ◽  
Body Mass ◽  
Population Based ◽  
Pooled Analysis

scholarly journals Body-Mass Index and Pancreatic Cancer Incidence: A Pooled Analysis of Nine Population-Based Cohort Studies With More Than 340,000 Japanese Subjects

2018 ◽  
Vol 28 (5) ◽  
pp. 245-252 ◽  
Author(s):  
Yuriko N. Koyanagi ◽  
Keitaro Matsuo ◽  
Hidemi Ito ◽  
Akiko Tamakoshi ◽  
Yumi Sugawara ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Body Mass Index ◽  
Cohort Studies ◽  
Body Mass ◽  
Cancer Incidence ◽  
Population Based ◽  
Pooled Analysis ◽  
Japanese Subjects

scholarly journals Body Mass Index and Risk of Gastric Cancer in Asian Adults: A Meta-Epidemiological Meta-Analysis of Population-Based Cohort Studies

2020 ◽  
Vol 52 (2) ◽  
pp. 369-373 ◽  
Author(s):  
Jong-Myon Bae
Keyword(s):  
Gastric Cancer ◽  
Body Mass Index ◽  
Body Weight ◽  
Cohort Studies ◽  
Body Mass ◽  
Meta Analysis ◽  
Population Based ◽  
Overweight And Obesity ◽  
Excess Body Weight ◽  
Inverse Association

PurposeA previous meta-analysis (MA) published in 2009 reported that excess body weight was associated with an increased risk of gastric cancer in non-Asians, but not in Asians. The aim was to conduct a meta-epidemiological MA (MEMA) to evaluate association between excess body weight and the risk of gastric cancer in Asian adults with using the proposed classification of weight by body mass index (BMI) in Asian adults.Materials and MethodsThe selection criteria were population-based prospective cohort studies that measured BMI of cohort participants and evaluated a risk of gastric cancer. Overweight group (OW) and obesity group (OB) were defined as 23.0-24.9 and ≥ 25.0, respectively. A group only showing results for BMI over 23.0 was defined as overweight and obesity group (OWB). Random effect model was applied if I<sup>2</sup> value was over 50%.ResultsAfter four new studies were added through citation discovery tools, seven cohort studies with 21 datasets were selected finally for MEMA. The I<sup>2</sup> value of OW, OB, and OWB were 76.1%, 83.5%, and 97.1%, respectively. Only OWB in men had a I<sup>2</sup> value below 50% (22.5%) and showed a statistical significance with inverse association (summary relative risk, 0.79; 95% confidence interval, 0.77 to 0.81).ConclusionThis MEMA supported the hypothesis that OW might be a protective factor in gastric cancer risk in Asian adults. It will be necessary to conduct additional cohort studies with lengthening follow-up periods and re-analyzing the effect of overweight and obesity classified by the Asian criteria.

Redefining standards for body mass index of the US population based on BRFSS data using mixtures

2016 ◽  
Vol 44 (2) ◽  
pp. 197-211 ◽  
Author(s):  
Tatjana Miljkovic ◽  
Saleem Shaik ◽  
Dragan Miljkovic
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Population Based ◽  
The Us

1480: The Association of Body Mass Index and Serum Prostate Specific Antigen Levels in a Population-Based Study

2005 ◽  
Vol 173 (4S) ◽  
pp. 401-401
Author(s):  
Javier Hernandez ◽  
Jacques Baillargeon ◽  
Brad Pollock ◽  
Alan R. Kristal ◽  
Patrick Bradshaw ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Prostate Specific Antigen ◽  
Body Mass ◽  
Specific Antigen ◽  
Population Based ◽  
Population Based Study ◽  
Serum Prostate Specific Antigen
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