scholarly journals Stolen Twin: Fascination and Curiosity/Twin Research Reports: Evolution of Sleep Length; Dental Treatment of Craniopagus Twins; Cryopreserved Double Embryo Transfer; Gender Options in Multiple Pregnancy/Current Events: Appendectomy in One Twin; Autistic Twin Marathon Runners; 3D Facial Recognition; Twin Biathletes

2014 ◽  
Vol 17 (1) ◽  
pp. 56-61 ◽  
Author(s):  
Nancy L. Segal
Keyword(s):  
Embryo Transfer ◽  
Dental Treatment ◽  
Facial Recognition ◽  
Multiple Pregnancy ◽  
Societal Implications ◽  
Marathon Runners ◽  
Twin Research ◽  
Current Events ◽  
Sleep Length ◽  
Double Embryo Transfer

The story of her allegedly stolen twin brother in Armenia is recounted by a ‘singleton twin’ living in the United States. The behavioral consequences and societal implications of this loss are considered. This case is followed by twin research reports on the evolution of sleep length, dental treatment of craniopagus conjoined twins, cryopreserved double embryo transfer (DET), and gender options in multiple pregnancy. Current events include the diagnosis of appendectomy in one identical twin, the accomplishments of autistic twin marathon runners, the power of three-dimensional (3D) facial recognition, and the goals of twin biathletes heading to the 2014 Sochi Olympics in Russia.

O-199 Proof of concept: implantation window must be wider than proposed. Report of seven twins after asynchronous double embryo transfer

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
A. Gosálvez Vega ◽  
M. Rodriguez Mazaira ◽  
N. Martin Fernandez ◽  
M. Iglesias Nuñez ◽  
M Brandt ◽  
...  
Keyword(s):  
Embryo Transfer ◽  
Developmental Stages ◽  
Multiple Pregnancy ◽  
Good Prognosis ◽  
Human Embryos ◽  
Proof Of Concept ◽  
Implantation Window ◽  
Study Results ◽  
Simultaneous Transfer ◽  
Double Embryo Transfer

Abstract Study question Can simultaneous transfer of two embryos that were cryopreserved at different stages (D3 and Blastocyst) be appropriate to enhance success in women with more than three failed embryo transfers? Summary answer Double asynchronous embryo transfer offered excellent results in RIF. Unexpectedly high twin rate suggests that embryo-endometrium synchrony is overemphasized. Implantation window must be wider. What is known already Transcriptomic signature of the endometrium has been investigated in the last few years trying to understand the best moment for embryo implantation. Nevertheless, the optimal period has not been well established yet in humans. Simultaneous transfer of two human embryos at different developmental stages (D3 and Blastocyst) on Day 4 was proposed to help couples who have had RIF. Study design, size, duration Observational case-control study. From April 2016 to January 2021, we offered double asynchronous embryo transfer only after Recurrent Implantation Failure (RIF). Two requirements were necessary: 1) Double embryo transfer was acceptable by the couple due to poor reproductive outcome. 2) Availability of two embryos cryopreserved at different stage (D3 and Blastocyst). Results were compared with good prognosis patients (all patients under 35 years in that period who had elected to transfer two day 3 cryopreserved embryos). Participants/materials, setting, methods Forty-five patients accepted to participate in the study. Results were compared with all patients (237) under 35 years where two D3 thawed embryos were transferred. All cases received same protocol (oral estradiol 6mg/d or vaginal estradiol 4mg/d until ultrasound showed endometrial growth) LH, P4 and E2 were monitored in all patients to detect spontaneous LH surge. All cases received transvaginal micronized progesterone 800 mg/d. Embryo transfers were ultrasound guided and Wallace Embryosure catheter was employed. Main results and the role of chance Limitations, reasons for caution Multiple pregnancy rate was unacceptably high. Therefore, it should not be suggested for good prognosis couples where single embryo transfer is clearly advidsed. Our main limitation was the combination of D3 embryos with blastocysts. The retrospective design make the results to be considered as a proof of concept. Wider implications of the findings Double asynchronic embryo transfer can offer new insights in the understanding of human implantation. The concept of implantation window is clearly challenged. Aiming to the center of the window is fine, but we still dońt know how wide is that center. Trial registration number not applicable

Elective single versus double embryo transfer: live birth outcome and patient acceptance in a prospective randomised trial

2015 ◽  
Vol 27 (5) ◽  
pp. 794 ◽  
Author(s):  
Nicolás Prados ◽  
Rocío Quiroga ◽  
Cinzia Caligara ◽  
Myriam Ruiz ◽  
Víctor Blasco ◽  
...  
Keyword(s):  
Embryo Transfer ◽  
Live Birth ◽  
Controlled Trial ◽  
Randomised Trial ◽  
Multiple Pregnancy ◽  
Multiple Births ◽  
Delivery Rate ◽  
Patient Acceptance ◽  
Increased Risk ◽  
Double Embryo Transfer

The purpose of this study was to determine which strategy of embryo transfer has a better trade-off in live birth delivery rate versus multiple pregnancy considering patient acceptance: elective single embryo transfer (eSET) or elective double embryo transfer (eDET). In all, 199 women <38 years of age undergoing their first IVF treatment in a private centre were included in a prospective open-label randomised controlled trial. Patients were randomised into four groups: (1) eSET on Day 3; (2) eSET on Day 5; (3) eDET on Day 3; and (4) eDET on Day 5. Per patient, main analysis included acceptance of assigned group, as well as multiple and live birth delivery rates of the fresh cycle. Secondary analysis included the rates of subsequent cryotransfers and the theoretical cumulative success rate. Of 98 patients selected for eSET, 40% refused and preferred eDET. The live birth delivery rate after eDET was significantly higher after eDET versus eSET (65% vs 42%, respectively; odds ratio = 1.6, 95% confidence interval 1.1–2.1). No multiple births were observed after eSET, compared with 35% after eDET. Although live birth delivery is higher with eDET, the increased risk of multiple births is avoided with eSET. Nearly half the patients refused eSET even after having been well informed about its benefits.

scholarly journals Human Dizygotic Twinning: Evolutionary-Based Explanations/Twin Research Reviews: Conjoined Twins in a Triplet Pregnancy; Double Embryo Transfer; Health Anxiety; Delayed Delivery of the Second Twin/In the Media: Digital Marketing Twins; Bereaved Twin at March for Our Lives; Exchange of Places; Football Players Reunite as Patriots

2018 ◽  
Vol 21 (4) ◽  
pp. 325-329
Author(s):  
Nancy L. Segal
Keyword(s):  
Embryo Transfer ◽  
Health Anxiety ◽  
Conjoined Twins ◽  
Digital Marketing ◽  
Football Players ◽  
Triplet Pregnancy ◽  
Twin Research ◽  
The Media ◽  
Second Twin ◽  
Double Embryo Transfer

Human twinning poses a conundrum for researchers, given that the female uterus is optimally designed to carry a single fetus. Evolutionary explanations of dizygotic (DZ or fraternal) twinning provide insight and understanding of this reproductive event. This review is followed by summaries of recent twin research and reports concerning twins in a triplet pregnancy, double embryo transfer; a twin study of health anxiety, and delayed delivery of the second twin. Twin events reported in the media include a pair of digital marketing twins, a speech by a bereaved twin at the March for Our Lives in Washington, D.C., twins who exchanged places, and a same-team reunion of twin football players.

Transfer of 2 Embryos Using a Double-Embryo Transfer Protocol Versus 2 Sequential Single-Embryo Transfers: The Impact on Multiple Pregnancy

2018 ◽  
Vol 25 (10) ◽  
pp. 1501-1508 ◽  
Author(s):  
Pedro A. A. Monteleone ◽  
Pedro F. M. Peregrino ◽  
Edmund C. Baracat ◽  
Paulo C. Serafini
Keyword(s):  
Embryo Transfer ◽  
Multiple Pregnancy ◽  
The Impact ◽  
Double Embryo Transfer ◽  
Transfer Protocol

scholarly journals Switched-at-Birth Twins in the Canary Islands: Revisited / Research Reports: Parkinson's Disease Discordance, Assisted Reproductive Technology and Neonatal Surgery, Double Embryo Transfer in a Cynomolgus Monkey, Mathematical Analysis of a Twin Convention Conundrum / Media Highlights: Twin Inventors, Basketball Duo, Two Comedians, Paired Designers, Two Musicians, Two Comedians, Twins’ Birth Interval

2013 ◽  
Vol 16 (4) ◽  
pp. 916-921 ◽  
Author(s):  
Nancy L. Segal
Keyword(s):  
Parkinson’S Disease ◽  
New York ◽  
Parkinson's Disease ◽  
Embryo Transfer ◽  
Cynomolgus Monkey ◽  
Human Genetics ◽  
Neonatal Surgery ◽  
Twin Research ◽  
True Story ◽  
Double Embryo Transfer

Switched-at-birth twins from Las Palmas, Gran Canaria in Spain drew international attention in May 2008 following news reports of their unexpected reunion. I visited Las Palmas in September 2009 to research this case and presented the findings in Segal and Blandón-Gitlin (Twin Research and Human Genetics, Vol. 13, 2010, pp. 115–119) and in a book, Someone Else's Twin: The True Story of Babies Switched at Birth (Segal, Prometheus Books, Amherst, New York, 2011). I traveled again to Las Palmas in November 2012 to meet with the twins, their families, and their attorneys and have updated my findings in this article. Next, new twin research on Parkinson's disease discordance, neonatal surgery, double embryo transfer in a cynomolgus monkey, and a convention conundrum are presented. Media highlights concerning twin inventors, basketball players, rappers, designers, musicians, and birth intervals are also summarized.

02 / Single and double embryo transfer provide similar live birth rates in frozen cycles

2018 ◽  
Author(s):  
Racca Annalisa ◽  
Panagiotis Drakopoulos ◽  
Samuel dos Santos Ribeiro ◽  
Christophe Blockeel
Keyword(s):  
Embryo Transfer ◽  
Live Birth ◽  
Birth Rates ◽  
Live Birth Rates ◽  
Double Embryo Transfer
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