scholarly journals Mutation induced in germ cells of the foetal female mouse

1960 ◽  
Vol 1 (1) ◽  
pp. 59-61 ◽  
Author(s):  
T. C. Carter
Keyword(s):  
Great Britain ◽  
Effective Dose ◽  
Germ Cells ◽  
Female Mouse ◽  
High Intensity ◽  
Human Population ◽  
Medical Radiology

In Great Britain by far the greater part of the genetically effective dose of man-made radiation to the human population is due to high-intensity irradiation of the gonads in medical radiology; about a third of it is received by post-natal males, a third by post-natal females, and a third by foetuses, mainly in the later stages of gestation (Osborn & Smith, 1956).

scholarly journals Primates and conservation priorities in Madagascar

Oryx ◽  
1986 ◽  
Vol 20 (4) ◽  
pp. 209-216 ◽  
Author(s):  
Jon I. Pollock
Keyword(s):  
Great Britain ◽  
Natural Resources ◽  
Human Population ◽  
Conservation Priorities ◽  
Behavioural Ecology ◽  
Primate Conservation ◽  
Conservation Of Natural Resources ◽  
Primate Society

Madagascar's conservation problems are many, but the Malagasy Government is working towards solutions, having recently passed into law a strategy that links development with the conservation of natural resources. The protection of the country's remaining forests is a key concern, both for the human population and for the non-human primates. The author is a primatologist and has a research background in behavioural ecology, reproduction and conservation, especially with prosimians. This article was first presented at the joint Primate Society of Great Britain/FFPS meeting on primate conservation in December 1985.

scholarly journals Plants causing dermatosis in humans

2020 ◽  
Vol 29 (1) ◽  
pp. 5-24
Author(s):  
Vaskrsija Janjić
Keyword(s):  
Great Britain ◽  
Direct Contact ◽  
Human Population ◽  
World Population ◽  
Cosmetic Products ◽  
The World ◽  
Different Types ◽  
Other Substances ◽  
The Usa ◽  
Everyday Problem

Many plants cause dermatosis in the human population, thus presenting an everyday problem for dermatologists and allergologists around the world. To this day it is still not known how common are plant-induced dermatosis. It is estimated that around 334 million people worldwide, or 3.5% of the world population, is affected by dermatosis each year. The onset of dermatitis is most common in the early childhood. Around 20% of children in Great Britain and 10% in the USA are affected by different types of dermatosis. It is believed that around 10,000 plant species can cause dermatosis in humans. Phytodermatosis are dermatosis caused by plants. They are usually induced by direct contact with a plant, but can also occur without a direct contact or be activated by the sun. Dermatosis which occur without a direct contact with the plant are observed in those cases where certain perfumes, cremes or other cosmetic products are used. Some cosmetic products contain substances such as eugenol, isoeugenol, cinnamaldehyde, colophonium, turpentines and other substances which originate from plants. Similarly, lichens, which are not plants, but organisms resulting from a fungi and algae symbiosis, produce usnic acids, which are most commonly used in sun protection products.

scholarly journals Serological evidence of continuing infection of swine in Great Britain with an influenza A virus (H3N2)

1978 ◽  
Vol 80 (3) ◽  
pp. 415-422 ◽  
Author(s):  
M. S. Chapman ◽  
P. H. Lamont ◽  
J. W. Harkness
Keyword(s):  
Great Britain ◽  
Influenza A Virus ◽  
Small Proportion ◽  
Human Population ◽  
Influenza A ◽  
Haemagglutination Inhibition ◽  
Swine Influenza ◽  
Seasonal Fluctuations ◽  
Serological Evidence ◽  
Serum Samples

SummarySerum samples collected from swine and cattle in Great Britain at various times between July 1971 and July 1977 were examined by haemagglutination-inhibition or single radial haemolysis methods for evidence of infection with influenza A (H3N2) viruses. A small proportion of swine sera collected in each year reacted in the tests but there was no evidence of infection in cattle. The significance of the findings is discussed, with particular reference to the seasonal fluctuations in the prevalence of antibody in swine observed during the period of the study, and their possible relevance to influenzal events in the human population. None of the sera tested had antibody to swine influenza strains (HSw1N1).

The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells

2007 ◽  
Vol 39 (3) ◽  
pp. 386-390 ◽  
Author(s):  
Liqin Cao ◽  
Hiroshi Shitara ◽  
Takuro Horii ◽  
Yasumitsu Nagao ◽  
Hiroshi Imai ◽  
...  
Keyword(s):  
Germ Cells ◽  
Female Mouse

Effects of FSH and testosterone on highly purified rat Sertoli cells: inhibin α-subunit mRNA expression and inhibin secretion are enhanced by FSH but not by testosterone

1989 ◽  
Vol 122 (3) ◽  
pp. 757-762 ◽  
Author(s):  
A. M. W. Toebosch ◽  
D. M. Robertson ◽  
I. A. Klaij ◽  
F. H. de Jong ◽  
J. A. Grootegoed
Keyword(s):  
Mrna Expression ◽  
Effective Dose ◽  
Sertoli Cell ◽  
Germ Cells ◽  
Sertoli Cells ◽  
Osmotic Shock ◽  
Shock Treatment ◽  
Α Subunit ◽  
Subunit Mrna ◽  
Old Rats

ABSTRACT The effects of FSH and testosterone on inhibin mRNA expression and inhibin production by highly purified Sertoli cell preparations were examined. Sertoli cells were isolated from testes of 22-day-old rats by sequential trypsin, collagenase and hyaluronidase treatments, with subsequent osmotic shock treatment on day 3 of culture. Contamination by peritubular and germ cells was <0·5 and 1–3% respectively. Intracellular and secreted inhibin levels were measured by radioimmunoassay, using Sertoli cells which were incubated for 24 h in the absence or presence of FSH and testosterone from days 4 to 5 of culture. FSH stimulated the cellular inhibin content and the secreted inhibin level by four- and sevenfold respectively, with a half-maximal effective dose of 5–50 ng/ml. Under the present incubation conditions, testosterone (1 μmol/l) had no effect on immunoreactive inhibin levels in either the presence or absence of FSH. Similarly, the expression of inhibin α-subunit mRNA was increased following FSH stimulation, whereas testosterone had no effect. The expression of inhibin βB-subunit mRNAs was not influenced by FSH or testosterone. It is concluded that highly purified Sertoli cell preparations, with a very low number of peritubular or germ cells, are fully responsive to FSH with respect to inhibin mRNA expression and inhibin production. Journal of Endocrinology (1989) 122, 757–762

Fate of germ cells in the B6.YDOM XY sex-reversed female mouse

1989 ◽  
Vol 27 ◽  
pp. 161
Author(s):  
T. Taketo-Hosotani ◽  
Y. Nishioka
Keyword(s):  
Germ Cells ◽  
Female Mouse

scholarly journals Potential role of miR-29b in modulation of Dnmt3a and Dnmt3b expression in primordial germ cells of female mouse embryos

RNA ◽  
2009 ◽  
Vol 15 (8) ◽  
pp. 1507-1514 ◽  
Author(s):  
S. Takada ◽  
E. Berezikov ◽  
Y. L. Choi ◽  
Y. Yamashita ◽  
H. Mano
Keyword(s):  
Germ Cells ◽  
Female Mouse ◽  
Potential Role ◽  
Primordial Germ Cells ◽  
Mouse Embryos ◽  
Dnmt3b Expression

Female mouse germ cells form synchronously dividing cysts

Development ◽  
1998 ◽  
Vol 125 (17) ◽  
pp. 3323-3328 ◽  
Author(s):  
M.E. Pepling ◽  
A.C. Spradling
Keyword(s):  
Confocal Microscopy ◽  
Germ Cells ◽  
Female Mouse ◽  
Progenitor Cell ◽  
Molecular Level ◽  
Cyst Formation ◽  
Intercellular Bridges ◽  
Cell Clusters ◽  
Key Characteristics ◽  
Germline Cyst

Oocytes from many invertebrates initiate development within distinctive cysts of interconnected cells, which are formed through synchronous divisions of a progenitor cell. Recently, processes underlying cyst formation have been extensively characterized at the molecular level in Drosophila. Defects in this process cause sterility in female flies. Early female mouse germ cells are organized as cell clusters as well, but it is uncertain whether these groups are similar to the cysts of invertebrates. We find that mouse germ cells are connected by intercellular bridges in the ovaries of 11.5 to 17.5 days postcoitum embryos; microtubules and organelles have been observed within these bridges. Confocal microscopy shows that cells within mouse clusters divide synchronously and frequently correspond in number to powers of two. Thus, female mouse germ cell clusters exhibit key characteristics of invertebrate germline cysts indicating that the process of germline cyst formation is conserved in the mouse.

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