scholarly journals Profiling Compliers and Noncompliers for Instrumental-Variable Analysis

2020 ◽  
Vol 28 (3) ◽  
pp. 435-444 ◽  
Author(s):  
Moritz Marbach ◽  
Dominik Hangartner

Instrumental-variable (IV) estimation is an essential method for applied researchers across the social and behavioral sciences who analyze randomized control trials marred by noncompliance or leverage partially exogenous treatment variation in observational studies. The potential outcome framework is a popular model to motivate the assumptions underlying the identification of the local average treatment effect (LATE) and to stratify the sample into compliers, always-takers, and never-takers. However, applied research has thus far paid little attention to the characteristics of compliers and noncompliers. Yet, profiling compliers and noncompliers is necessary to understand what subpopulation the researcher is making inferences about and an important first step in evaluating the external validity (or lack thereof) of the LATE estimated for compliers. In this letter, we discuss the assumptions necessary for profiling, which are weaker than the assumptions necessary for identifying the LATE if the instrument is randomly assigned. We introduce a simple and general method to characterize compliers, always-takers, and never-takers in terms of their covariates and provide easy-to-use software in R and STATA that implements our estimator. We hope that our method and software facilitate the profiling of compliers and noncompliers as a standard practice accompanying any IV analysis.

2021 ◽  
Author(s):  
Richard Breen ◽  
John Ermisch

Heterogeneous effects of treatment on an outcome is a plausible assumption to make about the vast majority of causal relationships studied in the social sciences. In these circumstances the IV estimator is often interpreted as yielding an estimate of a Local Average Treatment Effect (LATE): a marginal change in the outcome for those whose treatment is changed by the variation of the particular instrument in the study. Our aim is to explain the relationship between the LATE parameter and its IV estimator by using a simple model which is easily accessible to applied researchers, and by relating the model to examples from the demographic literature. A focus of the paper is how additional heterogeneity in the instrument – treatment relationship affects the properties and interpretation of the IV estimator. We show that if the two kinds of heterogeneity are correlated, then the LATE parameter combines both the underlying treatment effects and the parameters from the instrument – treatment relationship. It is then a more complicated concept than many researchers realise.


2019 ◽  
Author(s):  
Stefan Öberg

There has been a fundamental flaw in the conceptual design of many natural experiments used in the economics literature, particularly among studies aiming to estimate a local average treatment effect (LATE). When we use an instrumental variable (IV) to estimate a LATE, the IV only has an indirect effect on the treatment of interest. Such IVs do not work as intended and will produce severely biased and/or uninterpretable results. This comment demonstrates that the LATE does not work as previously thought and explains why using the natural experiment proposed by Angrist and Evans (1998) as the example.


PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0249642
Author(s):  
Byeong Yeob Choi

Instrumental variable (IV) analysis is used to address unmeasured confounding when comparing two nonrandomized treatment groups. The local average treatment effect (LATE) is a causal estimand that can be identified by an IV. The LATE approach is appealing because its identification relies on weaker assumptions than those in other IV approaches requiring a homogeneous treatment effect assumption. If the instrument is confounded by some covariates, then one can use a weighting estimator, for which the outcome and treatment are weighted by instrumental propensity scores. The weighting estimator for the LATE has a large variance when the IV is weak and the target population, i.e., the compliers, is relatively small. We propose a truncated LATE that can be estimated more reliably than the regular LATE in the presence of a weak IV. In our approach, subjects who contribute substantially to the weak IV are identified by their probabilities of being compliers, and they are removed based on a pre-specified threshold. We discuss interpretation of the proposed estimand and related inference method. Simulation and real data experiments demonstrate that the proposed truncated LATE can be estimated more precisely than the standard LATE.


2013 ◽  
Vol 21 (4) ◽  
pp. 492-506 ◽  
Author(s):  
Peter M. Aronow ◽  
Allison Carnegie

Political scientists frequently use instrumental variables (IV) estimation to estimate the causal effect of an endogenous treatment variable. However, when the treatment effect is heterogeneous, this estimation strategy only recovers the local average treatment effect (LATE). The LATE is an average treatment effect (ATE) for a subset of the population: units that receive treatment if and only if they are induced by an exogenous IV. However, researchers may instead be interested in the ATE for the entire population of interest. In this article, we develop a simple reweighting method for estimating the ATE, shedding light on the identification challenge posed in moving from the LATE to the ATE. We apply our method to two published experiments in political science in which we demonstrate that the LATE has the potential to substantively differ from the ATE.


Biometrika ◽  
2021 ◽  
Author(s):  
Linbo Wang ◽  
Yuexia Zhang ◽  
Thomas S Richardson ◽  
James M Robins

Abstract Instrumental variables are widely used to deal with unmeasured confounding in observational studies and imperfect randomized controlled trials. In these studies, researchers often target the so-called local average treatment effect as it is identifiable under mild conditions. In this paper, we consider estimation of the local average treatment effect under the binary instrumental variable model. We discuss the challenges for causal estimation with a binary outcome, and show that surprisingly, it can be more difficult than the case with a continuous outcome. We propose novel modelling and estimating procedures that improve upon existing proposals in terms of model congeniality, interpretability, robustness and efficiency. Our approach is illustrated via simulation studies and a real data analysis.


2018 ◽  
Vol 238 (3-4) ◽  
pp. 243-293 ◽  
Author(s):  
Jason Ansel ◽  
Han Hong ◽  
and Jessie Li

Abstract We investigate estimation and inference of the (local) average treatment effect parameter when a binary instrumental variable is generated by a randomized or conditionally randomized experiment. Under i.i.d. sampling, we show that adding covariates and their interactions with the instrument will weakly improve estimation precision of the (local) average treatment effect, but the robust OLS (2SLS) standard errors will no longer be valid. We provide an analytic correction that is easy to implement and demonstrate through Monte Carlo simulations and an empirical application the interacted estimator’s efficiency gains over the unadjusted estimator and the uninteracted covariate adjusted estimator. We also generalize our results to covariate adaptive randomization where the treatment assignment is not i.i.d., thus extending the recent contributions of Bugni, F., I.A. Canay, A.M. Shaikh (2017a), Inference Under Covariate-Adaptive Randomization. Working Paper and Bugni, F., I.A. Canay, A.M. Shaikh (2017b), Inference Under Covariate-Adaptive Randomization with Multiple Treatments. Working Paper to allow for the case of non-compliance.


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