scholarly journals Multistate Outbreak of an Emerging Burkholderia cepacia Complex Strain Associated With Contaminated Oral Liquid Docusate Sodium

2018 ◽  
Vol 39 (2) ◽  
pp. 237-239 ◽  
Author(s):  
Ibukunoluwa C. Akinboyo ◽  
Anna C. Sick-Samuels ◽  
Emily Singeltary ◽  
James Fackler ◽  
Judith Ascenzi ◽  
...  
Keyword(s):  
Burkholderia Cepacia ◽  
Burkholderia Cepacia Complex ◽  
Oral Liquid ◽  
Complex Strain ◽  
Docusate Sodium

scholarly journals Study of class I integron in a Burkholderia cepacia complex strain isolated from blood colture

2011 ◽  
Vol 26 (2) ◽  
Author(s):  
Linda Furlanis ◽  
Lucia Corich ◽  
Lucilla Dolzani ◽  
Enrico Angelo Tonin ◽  
Cristina Lagatolla
Keyword(s):  
Burkholderia Cepacia ◽  
Class I ◽  
Burkholderia Cepacia Complex ◽  
Complex Strain

scholarly journals A multistate investigation of health care–associated Burkholderia cepacia complex infections related to liquid docusate sodium contamination, January-October 2016

2018 ◽  
Vol 46 (6) ◽  
pp. 649-655 ◽  
Author(s):  
Janet Glowicz ◽  
Matthew Crist ◽  
Carolyn Gould ◽  
Heather Moulton-Meissner ◽  
Judith Noble-Wang ◽  
...  
Keyword(s):  
Health Care ◽  
Burkholderia Cepacia ◽  
Burkholderia Cepacia Complex ◽  
Docusate Sodium

An epidemic Burkholderia cepacia complex strain identified in soil

The Lancet ◽  
2002 ◽  
Vol 359 (9322) ◽  
pp. 2002-2003 ◽  
Author(s):  
John J LiPuma ◽  
Theodore Spilker ◽  
Tom Coenye ◽  
Carlos F Gonzalez
Keyword(s):  
Burkholderia Cepacia ◽  
Burkholderia Cepacia Complex ◽  
Complex Strain

scholarly journals Draft Genome Sequence of a Burkholderia cepacia Complex Strain Isolated from a Human Intra-abdominal Abscess

2021 ◽  
Vol 10 (11) ◽  
Author(s):  
Yuting Zhai ◽  
Kathryn E. DeSear ◽  
Kartik Cherabuddi ◽  
J. Glenn Morris ◽  
Kwangcheol C. Jeong
Keyword(s):  
Genome Sequence ◽  
Burkholderia Cepacia ◽  
Draft Genome ◽  
Immunocompetent Patient ◽  
Burkholderia Cepacia Complex ◽  
Draft Genome Sequence ◽  
Abdominal Abscess ◽  
Opportunistic Pathogens ◽  
Content Type ◽  
Complex Strain

ABSTRACT Burkholderia cepacia complex (Bcc) bacteria are opportunistic pathogens with high transmissibility and mortality. Here, we report the draft genome sequence of a Bcc strain isolated from a deep abscess culture in an immunocompetent patient with no relevant prior medical history.

scholarly journals Identical Burkholderia cepacia complex strain types isolated from multiple patients attending a hospital in Brazil

2006 ◽  
Vol 55 (2) ◽  
pp. 247-249 ◽  
Author(s):  
Wail Assaad ◽  
Marcelo Magalhães ◽  
Maria Plesa ◽  
C. Anthony Hart ◽  
Pierre Cornelis ◽  
...  
Keyword(s):  
Burkholderia Cepacia ◽  
Burkholderia Cepacia Complex ◽  
Complex Strain ◽  
Multiple Patients

scholarly journals Comparison of Microbiological Characteristics and Genetic Diversity between Burkholderia cepacia Complex Isolates from Vascular Access and Other Clinical Infections

2020 ◽  
Vol 9 (1) ◽  
pp. 51
Author(s):  
Min Yi Wong ◽  
Yuan-Hsi Tseng ◽  
Tsung-Yu Huang ◽  
Bor-Shyh Lin ◽  
Chun-Wu Tung ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Vascular Access ◽  
Burkholderia Cepacia ◽  
Bacterial Species ◽  
Diversity Indices ◽  
Burkholderia Cepacia Complex ◽  
Reca Gene ◽  
Clinical Effects ◽  
Environmental Distribution ◽  
Microbiological Characteristics

Burkholderia cepacia complex (BCC) is a group of closely related bacteria with widespread environmental distribution. BCC bacteria are opportunistic pathogens that cause nosocomial infections in patients, especially cystic fibrosis (CF). Multilocus sequence typing (MLST) is used nowadays to differentiate species within the BCC complex. This study collected 41 BCC isolates from vascular access infections (VAIs) and other clinical infections between 2014 and 2020. We preliminarily identified bacterial isolates using standard biochemical procedures and further conducted recA gene sequencing and MLST for species identification. We determined genetic diversity indices using bioinformatics software. We studied 14 isolates retrieved from patients with VAIs and observed that Burkholderia cepacia was the predominant bacterial species, and B. contaminans followed by B. cenocepacia were mainly retrieved from patients with other infections. According to MLST data, we identified that all B. contaminans isolates belonged to ST102, while a wide variety of sequence types (STs) were found in B. cenocepacia isolates. In summary, the high diversity and easy transmission of BCC increase BCC infections, which provides insights into their potential clinical effects in non-CF infections.

Multi-institutional outbreak of Burkholderia cepacia complex associated with contaminated mannitol solution prepared in compounding pharmacy

2013 ◽  
Vol 41 (11) ◽  
pp. 1038-1042 ◽  
Author(s):  
Maria Beatriz Souza Dias ◽  
Larissa G.T. Cavassin ◽  
Valeska Stempliuk ◽  
Luciene S. Xavier ◽  
Renata D. Lobo ◽  
...  
Keyword(s):  
Burkholderia Cepacia ◽  
Burkholderia Cepacia Complex ◽  
Mannitol Solution

Clonal diversity among Burkholderia cepacia complex isolates from cystic fibrosis patients in a reference unit

2013 ◽  
Vol 31 (10) ◽  
pp. 665-668 ◽  
Author(s):  
Laura Barrado ◽  
M. Teresa Martinez ◽  
Jennifer Villa ◽  
M. Ángeles Orellana ◽  
Esther Viedma ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Burkholderia Cepacia ◽  
Clonal Diversity ◽  
Burkholderia Cepacia Complex

scholarly journals Differential Persistence among Genomovars of the Burkholderia cepacia Complex in a Murine Model of Pulmonary Infection

2002 ◽  
Vol 70 (5) ◽  
pp. 2715-2720 ◽  
Author(s):  
Karen K. Chu ◽  
Donald J. Davidson ◽  
T. Keith Halsey ◽  
Jacqueline W. Chung ◽  
David P. Speert
Keyword(s):  
Cystic Fibrosis ◽  
Clinical Outcomes ◽  
Murine Model ◽  
Burkholderia Cepacia ◽  
Pulmonary Infection ◽  
Burkholderia Cepacia Complex ◽  
Clinical Infection ◽  
Minimal Toxicity

ABSTRACT Cystic fibrosis patients infected with strains from different genomovars of the Burkholderia cepacia complex can experience diverse clinical outcomes. To identify genomovar-specific determinants that might be responsible for these differences, we developed a pulmonary model of infection in BALB/c mice. Mice were rendered leukopenic by administration of cyclophosphamide prior to intranasal challenge with 1.6 × 104 bacteria. Five of six genomovar II strains persisted at stable numbers in the lungs until day 16 with minimal toxicity, whereas zero of seven genomovar III strains persisted but resulted in variable toxicity. We have developed a chronic pulmonary model of B. cepacia infection which reveals differences among genomovars in terms of clinical infection outcome.

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