scholarly journals Measures to Prevent and Control Vancomycin-Resistant Enterococci: Do They Really Matter?

2017 ◽  
Vol 38 (4) ◽  
pp. 507-509 ◽  
Author(s):  
Hilary Humphreys
Keyword(s):  
Vancomycin Resistant Enterococci ◽  
Vancomycin Resistant ◽  
And Control

scholarly journals Transmission of Vancomycin-Resistant Enterococci in the Hospital Setting: Uncovering the Patient–Environment Interplay

2020 ◽  
Vol 8 (2) ◽  
pp. 203 ◽  
Author(s):  
Carlos L. Correa-Martinez ◽  
Hauke Tönnies ◽  
Neele J. Froböse ◽  
Alexander Mellmann ◽  
Stefanie Kampmeier
Keyword(s):  
Core Genome ◽  
Hospital Setting ◽  
Hospital Environment ◽  
Environmental Isolates ◽  
Resistance Determinants ◽  
Vancomycin Resistant Enterococci ◽  
Vancomycin Resistant ◽  
And Control ◽  
Sequence Types

Vancomycin-resistant enterococci (VRE) are relevant nosocomial pathogens with an increasing incidence in the last decades. Their transmission is optimal in the hospital setting, as it offers two potential, large reservoirs that are closely related: susceptible patients and their environment. Here we investigate the role of the hospital environment in the nosocomial transmission of VRE by establishing concrete links between contaminated surfaces and colonized/infected patients in outbreak and non-outbreak settings. Environmental and patient VRE isolates were collected between 2013 and 2019 and analyzed by whole-genome sequencing (WGS), subsequent multilocus sequence typing (MLST), and core genome (cg) MLST. Pairs of isolates differing in <3 alleles were rated as closely related, making a transmission likely. Fifty-three environmental VRE isolates were analyzed. MLST sequence types (ST) ST203 (50.0%), ST192 (21.3%), ST117 (17.3%), ST721 (8.8%), ST80 (2%), and ST1489 (0.7%) were detected, carrying the resistance determinants vanA (72.7%), vanB (24%), or both (3.3%). Of the 53 environmental isolates, 51 were found to form five clusters with genetically related patient isolates (n = 97 isolates). WGS confirms the role of the environment in the transmission dynamics of VRE in both the outbreak and non-outbreak settings, highlighting the importance of prevention and control of VRE spread.

scholarly journals Modeling the regional spread and control of vancomycin-resistant enterococci

2013 ◽  
Vol 41 (8) ◽  
pp. 668-673 ◽  
Author(s):  
Bruce Y. Lee ◽  
S. Levent Yilmaz ◽  
Kim F. Wong ◽  
Sarah M. Bartsch ◽  
Stephen Eubank ◽  
...  
Keyword(s):  
Vancomycin Resistant Enterococci ◽  
Vancomycin Resistant ◽  
And Control

EPIDEMIOLOGY AND CONTROL OF VANCOMYCIN‐RESISTANT ENTEROCOCCI (VRE) IN A RENAL UNIT

Nephrology ◽  
2000 ◽  
Vol 5 (3) ◽  
pp. A107-A107
Author(s):  
MacGinley R ◽  
Bartley P ◽  
Schooneveldt J ◽  
Isbel N ◽  
Campbell Sc ◽  
...  
Keyword(s):  
Renal Unit ◽  
Vancomycin Resistant Enterococci ◽  
Vancomycin Resistant ◽  
And Control

Persistent environmental reservoirs for Vancomycin-resistant enterococci requiring repeated decontamination to achieve eradication

2002 ◽  
Vol 3 (3) ◽  
pp. 10-13 ◽  
Author(s):  
T Sexton ◽  
E Creamer ◽  
M Turley ◽  
E Smyth ◽  
E Humphreys
Keyword(s):  
Daily Basis ◽  
Control Measures ◽  
Vancomycin Resistant Enterococci ◽  
Cleaning Equipment ◽  
Hospital Infection Control ◽  
Vancomycin Resistant ◽  
Environmental Measures ◽  
And Control ◽  
Predominant Strain

V ancomycin-resistant enterococci (VRE) are increasingly recognised nosocomial pathogens in clinical areas with high antibiotic usage. Patients with chronic renal failure, including those requiring haemodialysis, are at particular risk. Investigation and control of an outbreak of VRE in two renal wards, highlighting mattresses as reservoirs and environmental measures to control VRE are reported in this paper. Outbreak control measures included standard isolation in accordance with the Recommendations of the Hospital Infection Control Practices Advisory Committee (HICPAC). Patients were screened on admission and weekly using a rectal swab. The inanimate environment including mattresses was also screened. Enhanced environmental decontamination was performed on a daily basis. The outbreak continued over a 20-week period with most cases occurring in the first 6 weeks. The results of screening indicated that 59 (13%) of 451 patients and 54 (8.3%) of 647 environmental samples were positive for VRE. VRE was isolated from 35 (8%) of 433 mattresses, 12 (8.1%) of 148 environmental ledges, 4 (8%) of 50 toilets, and 3 (18.8%) of 16 items of cleaning equipment. Molecular typing indicated that a predominant strain was also implicated in mattress contamination, thus highlighting a potential and important reservoir for transmission of VRE. Difficulty with eradication of VRE from the environment was encountered despite enhanced cleaning regimens and a doubling of use of disinfectant was necessary. Restriction of antibiotics, hand hygiene, hygiene and education are the cornerstone of VRE prevention and control. Lessons from this outbreak highlight the role of the environment in VRE transmission and the need for attention to the environment, especially mattress decontamination.

scholarly journals Outbreak of vancomycin-resistant enterococcus on a haematology ward: management and control

2017 ◽  
Vol 18 (3) ◽  
pp. 149-153 ◽  
Author(s):  
Diego García Martínez de Artola ◽  
Beatriz Castro ◽  
María José Ramos ◽  
Zaida Díaz Cuevas ◽  
Sunil Lakhwani ◽  
...  
Keyword(s):  
Infection Control ◽  
Multidisciplinary Approach ◽  
Bloodstream Infections ◽  
Vancomycin Resistant Enterococcus ◽  
Control Policies ◽  
Vancomycin Resistant Enterococci ◽  
Vancomycin Resistant ◽  
Control And Management ◽  
And Control

Vancomycin-resistant enterococci (VRE) infections and outbreaks are still infrequent in Spain. A six-month outbreak, which took place in a haematology ward, its control and management are described in this study. A total of 22 patients were colonised and two bloodstream infections occurred during this period. Even though there were two waves of new colonised patients, a multidisciplinary approach, quick interventions and enhanced infection control policies were required in order to control this outbreak.

Epidemiology and control of vancomycin-resistant enterococci (VRE) in a renal unit

1998 ◽  
Vol 40 (2) ◽  
pp. 115-124 ◽  
Author(s):  
A.R. Brown ◽  
S.G.B. Amyes ◽  
R. Paton ◽  
W.D. Plant ◽  
G.M. Stevenson ◽  
...  
Keyword(s):  
Renal Unit ◽  
Vancomycin Resistant Enterococci ◽  
Vancomycin Resistant ◽  
And Control

EPIDEMIOLOGY AND CONTROL OF VANCOMYCIN‐RESISTANT ENTEROCOCCI (VRE) IN A RENAL UNIT

Nephrology ◽  
2000 ◽  
Vol 5 (3) ◽  
pp. A107-A107
Author(s):  
MacGinley R ◽  
Bartley P ◽  
Schooneveldt J ◽  
Isbel N ◽  
Campbell Sc ◽  
...  
Keyword(s):  
Renal Unit ◽  
Vancomycin Resistant Enterococci ◽  
Vancomycin Resistant ◽  
And Control
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