scholarly journals 2053

2017 ◽  
Vol 1 (S1) ◽  
pp. 43-43
Author(s):  
Yue Zang ◽  
Tom Greene ◽  
Trent Matheson ◽  
Erin Rothwell

OBJECTIVES/SPECIFIC AIMS: In this study, we propose to investigate effectiveness of 2 core services provided by the Center for Clinical and Translational Science (CCTS), home for CTSA program in the School of Medicine at the University of Utah. METHODS/STUDY POPULATION: We will apply a longitudinal database of research and tenure track faculty (n>600) in the School of Medicine at the University of Utah from 2006 to 2016 to estimate the effect of initial usage of the biostatistics and clinical services cores of the University of Utah CCTS on the probability of (a) ≥1 peer reviewed publication, (b) external grant funding, and (c) academic promotion within 1, 2, and 3 years after the initial contact. We will apply a “new users” design (Hernan et al., Epidemiology, 2008; 19: 766–779) to compare the outcomes of faculty initiating use of the 2 CCTS cores Versus faculty without prior use of these cores in a series of cohorts defined by the calendar year of initial contract with the 2 cores, with covariate adjustment performed within each cohort to account for measured confounders. Separate outcome models will be specified for each cohort, but the statistical models will be fit to stacked augmented data sets which include the data from each cohort. Using the stacked data set, results will be pooled across each of the cohorts to increase statistical power. Robust sandwich estimates of standard errors will be used to account for the inclusion of multiple assessments for each faculty member. RESULTS/ANTICIPATED RESULTS: Estimates of the effect of initiation of new CTSA usage on academic productivity outcomes will be obtained, and provided in conjunction with sensitivity analyses to address the potential impact of uncontrolled confounding. DISCUSSION/SIGNIFICANCE OF IMPACT: The proposed evaluation strategy should overcome some of the biases inherent in typical metrics for effectiveness of CTSA programs, and will be applied to evaluate success of future initiatives.

1994 ◽  
Vol 58 (3) ◽  
pp. 313-320 ◽  
Author(s):  
G. Simm ◽  
R. F. Veerkamp ◽  
P. Persaud

AbstractThe aim of this study was to examine the relationship between pedigree index for kg fat plus protein and the financial margins between milk returns and food, health and reproduction costs in individual lactations. Records of milk and milk component production, food intake, health and reproduction were obtained for individual Holstein-Friesian cows over 38 weeks of lactation over a 7-year period, at the University of Edinburgh/Scottish Agricultural College Langhill dairy cattle research centre. Records for a total of 302 lactations were collected. Milk prices, input costs and margins were calculated for individual animals, using 1989/90 values. Regressions of margin over food costs (MF) and margin over food, health and reproduction costs (MFHR) on pedigree index (PI) for kg fat plus protein were all positive and ranged from £2·50± 3·00 per kg PI for MFHR for heifers, to £6·50 ± 2·10 per kg PI for MFHR for all animals. The lower regression for heifers was attributed to higher reproduction costs in animals of higher genetic merit, though the standard error for the regression estimated in this smaller data set was high. Sensitivity analyses showed that the regression coefficients remained very similar, even with ±50% changes in food, health or reproduction costs. It was concluded that selection on PI for kg fat plus protein is likely to lead to increased margin over food, health and reproduction costs.


2015 ◽  
Vol 5 (2) ◽  
pp. 137-148 ◽  
Author(s):  
Jeremy N.V Miles ◽  
Priscillia Hunt

Purpose – In applied psychology research settings, such as criminal psychology, missing data are to be expected. Missing data can cause problems with both biased estimates and lack of statistical power. The paper aims to discuss these issues. Design/methodology/approach – Recently, sophisticated methods for appropriately dealing with missing data, so as to minimize bias and to maximize power have been developed. In this paper the authors use an artificial data set to demonstrate the problems that can arise with missing data, and make naïve attempts to handle data sets where some data are missing. Findings – With the artificial data set, and a data set comprising of the results of a survey investigating prices paid for recreational and medical marijuana, the authors demonstrate the use of multiple imputation and maximum likelihood estimation for obtaining appropriate estimates and standard errors when data are missing. Originality/value – Missing data are ubiquitous in applied research. This paper demonstrates that techniques for handling missing data are accessible and should be employed by researchers.


2017 ◽  
Vol 26 (2) ◽  
pp. 323-334 ◽  
Author(s):  
Piyabute Fuangkhon

AbstractMulticlass contour-preserving classification (MCOV) has been used to preserve the contour of the data set and improve the classification accuracy of a feed-forward neural network. It synthesizes two types of new instances, called fundamental multiclass outpost vector (FMCOV) and additional multiclass outpost vector (AMCOV), in the middle of the decision boundary between consecutive classes of data. This paper presents a comparison on the generalization of an inclusion of FMCOVs, AMCOVs, and both MCOVs on the final training sets with support vector machine (SVM). The experiments were carried out using MATLAB R2015a and LIBSVM v3.20 on seven types of the final training sets generated from each of the synthetic and real-world data sets from the University of California Irvine machine learning repository and the ELENA project. The experimental results confirm that an inclusion of FMCOVs on the final training sets having raw data can improve the SVM classification accuracy significantly.


2021 ◽  
Vol 2 (1) ◽  
pp. 96-112
Author(s):  
Ben Wesley Beachy

This article is a basic quantitative analysis of widowhood and remarriage trends among several Plain churches. When compared to past studies of similar topics, a remarkable consistency of findings across both time and sect can be identified. Bereaved Plain spouses have largely experienced widowhood along separate gender-specific paths, in data sets ranging from 1730 to 2019 and from relatively liberal to traditional communities. Positing that much of Amish and Amish Mennonite society is designed to socialize and retain children, this article offers opportunities for deeper study of the parental roles undergirding that society. The primary research suggestions include spousal function in the context of family life, the various factors influencing the health of bereaved spouses, and the "marriage squeeze" present in many churches. The central data sets used in this study were collected from the 2019 edition of the Amish Mennonite Directory and the 2015 Church Directory of the Lancaster County Amish and Outlying Daughter Settlements. These reference books were sampled on a one-in-five and one-in-three basis, respectively. The resultant widowhood cases were contextualized by widowhood cases from studies by Elmer Lewis Smith and researchers at the University of Maryland School of Medicine.


2020 ◽  
Vol 13 (2) ◽  
pp. 373-404 ◽  
Author(s):  
Andrew M. Sayer ◽  
Yves Govaerts ◽  
Pekka Kolmonen ◽  
Antti Lipponen ◽  
Marta Luffarelli ◽  
...  

Abstract. Recent years have seen the increasing inclusion of per-retrieval prognostic (predictive) uncertainty estimates within satellite aerosol optical depth (AOD) data sets, providing users with quantitative tools to assist in the optimal use of these data. Prognostic estimates contrast with diagnostic (i.e. relative to some external truth) ones, which are typically obtained using sensitivity and/or validation analyses. Up to now, however, the quality of these uncertainty estimates has not been routinely assessed. This study presents a review of existing prognostic and diagnostic approaches for quantifying uncertainty in satellite AOD retrievals, and it presents a general framework to evaluate them based on the expected statistical properties of ensembles of estimated uncertainties and actual retrieval errors. It is hoped that this framework will be adopted as a complement to existing AOD validation exercises; it is not restricted to AOD and can in principle be applied to other quantities for which a reference validation data set is available. This framework is then applied to assess the uncertainties provided by several satellite data sets (seven over land, five over water), which draw on methods from the empirical to sensitivity analyses to formal error propagation, at 12 Aerosol Robotic Network (AERONET) sites. The AERONET sites are divided into those for which it is expected that the techniques will perform well and those for which some complexity about the site may provide a more severe test. Overall, all techniques show some skill in that larger estimated uncertainties are generally associated with larger observed errors, although they are sometimes poorly calibrated (i.e. too small or too large in magnitude). No technique uniformly performs best. For powerful formal uncertainty propagation approaches such as optimal estimation, the results illustrate some of the difficulties in appropriate population of the covariance matrices required by the technique. When the data sets are confronted by a situation strongly counter to the retrieval forward model (e.g. potentially mixed land–water surfaces or aerosol optical properties outside the family of assumptions), some algorithms fail to provide a retrieval, while others do but with a quantitatively unreliable uncertainty estimate. The discussion suggests paths forward for the refinement of these techniques.


2017 ◽  
Vol 1 (S1) ◽  
pp. 1-1
Author(s):  
Andrew Middleton Redd

OBJECTIVES/SPECIFIC AIMS: This research seeks to create a next generation documentation system that exists independent of but is complimentary to the packaging system in R. The new documentation can be manipulated programmatically as with all R objects. It also implements multiple translators for creating documentation from different sources, including documentation pages written in latex and code comments. METHODS/STUDY POPULATION: This work is based on input from the R Documentation Task Force, which is a working group, supported by the R Consortium and the University of Utah Center for Clinical and Translational Science, consisting of R Core developers, representatives from the R Consortium member companies and community developers with relevant interest in documentation. An abstraction of the documentation currently in use was created and extended. This abstraction was translated to a class system in R so that documentation can be stored and manipulated in R. RESULTS/ANTICIPATED RESULTS: The class system representing the documentation and the tools for creating the translators are currently being implemented in R. A preview of the system is scheduled to be available at the time of the conference. DISCUSSION/SIGNIFICANCE OF IMPACT: Good documentation is critical for researchers to disseminate computational research methods, either internally or externally to their organization. This work will facilitate the creation of documentation by making documentation immediately accessible and promote documentation consumption through multiple outputs which can be implemented by developers.


2019 ◽  
Vol 11 (2) ◽  
pp. 895-920
Author(s):  
Katrin Latarius ◽  
Ursula Schauer ◽  
Andreas Wisotzki

Abstract. During summer 2014 and summer 2015 two autonomous Seagliders were operated over several months close to the ice edge of the East Greenland Current to capture the near-surface freshwater distribution in the western Greenland Sea. The mission in 2015 included an excursion onto the East Greenland Shelf into the Norske Trough. Temperature, salinity and drift data were obtained in the upper 500 to 1000 m with high spatial resolution. The data set presented here gives the opportunity to analyze the freshwater distribution and possible sources for two different summer situations. During summer 2014 the ice retreat at the rim of the Greenland Sea Gyre was only marginal. The Seagliders were never able to reach the shelf break nor regions where the ice just melted. During summer 2015 the ice retreat was clearly visible. Finally, ice was present only on the shallow shelves. The Seaglider crossed regions with recent ice melt and was even able to reach the entrance of the Norske Trough. The data processing for these glider measurements was conducted at Alfred Wegener Institute (AWI). The first part consists of the Seaglider Toolbox from the University of Each Anglia; the second was exclusively composed for the data from the Greenland Sea. The final hydrographic, position and drift data sets can be downloaded from https://doi.org/10.1594/PANGAEA.893896 (Latarius et al., 2018).


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