scholarly journals Selection of SARS-Coronavirus-specific B cell epitopes by phage peptide library screening and evaluation of the immunological effect of epitope-based peptides on mice

Virology ◽  
2007 ◽  
Vol 359 (2) ◽  
pp. 264-274 ◽  
Author(s):  
Hua Yu ◽  
Li-Fang Jiang ◽  
Dan-Yun Fang ◽  
Hui-Jun Yan ◽  
Jing-Jiao Zhou ◽  
...  
Keyword(s):  
B Cell ◽  
Peptide Library ◽  
Library Screening ◽  
Sars Coronavirus ◽  
B Cell Epitopes ◽  
Immunological Effect ◽  
Phage Peptide Library ◽  
Selection Of

Effect of adjuvant formulations on the selection of B-cell epitopes expressed by a malaria peptide vaccine

Vaccine ◽  
1992 ◽  
Vol 10 (8) ◽  
pp. 547-550 ◽  
Author(s):  
Pascal Millet ◽  
Marcia L. Kalish ◽  
William E. Collins ◽  
Robert L. Hunter
Keyword(s):  
B Cell ◽  
Peptide Vaccine ◽  
B Cell Epitopes ◽  
Selection Of

scholarly journals Selection of Poly-α 2,8-Sialic Acid Mimotopes from a Random Phage Peptide Library and Analysis of Their Bioactivity

2004 ◽  
Vol 279 (29) ◽  
pp. 30707-30714 ◽  
Author(s):  
Pascal Torregrossa ◽  
Lone Buhl ◽  
Mircea Bancila ◽  
Pascale Durbec ◽  
Claus Schafer ◽  
...  
Keyword(s):  
Sialic Acid ◽  
Peptide Library ◽  
Phage Peptide Library ◽  
Selection Of

SELECTION OF CRYPTIC B-CELL EPITOPES USING INFORMATIONAL ANALYSIS OF PROTEIN SEQUENSES

2006 ◽  
Vol 04 (02) ◽  
pp. 389-402 ◽  
Author(s):  
ELENA SVIRSHCHEVSKAYA ◽  
LUDMILA ALEKSEEVA ◽  
ALEXEI MARCHENKO ◽  
SERGEI BENEVOLENSKII ◽  
VALENTINA M. BERZHEC ◽  
...  
Keyword(s):  
B Cell ◽  
Information Structure ◽  
Cell Epitope ◽  
Protein Sequences ◽  
Major Protein ◽  
Protein Antigens ◽  
B Cell Epitopes ◽  
Fel D 1 ◽  
B Cell Epitope ◽  
Selection Of

Sub-unit vaccines are synthetic or recombinant peptides representing T- or B-cell epitopes of major protein antigens from a particular pathogen. Epitope selection requires the synthesis of peptides that overlap the protein sequences and screening for the most effective ones. In this study a new method of immunogenic peptide selection based on the analysis of information structure of protein sequences is suggested. The analysis of known B-cell epitope location in the information structure of Aspergillus fumigatus proteins Asp f 2 and Asp f 3 has shown that epitopes are scattered along the sequences of proteins for the exception of sites with Increased Degree Information Coordination (IDIC). Based on these results peptides from different allergens such as Asp f 2, Der p 1, and Fel d 1 were selected and produced in a recombinant form in the context of yeast virus-like particles (VLPs). Immunization of mice with VLPs containing peptides form allergens has induced the production of IgG able to recognize full-length antigens. This result suggests that the analysis of information structure of proteins can be used for the selection of peptides possessing cryptic B-cell epitope activity.

scholarly journals A novel method for selection of chymotrypsin inhibitors from a phage peptide library

IUBMB Life ◽  
1998 ◽  
Vol 45 (1) ◽  
pp. 155-161
Author(s):  
Ying Liu ◽  
Bin Li ◽  
Shu Zhang ◽  
Tianyu Li ◽  
Hui Zhou ◽  
...  
Keyword(s):  
Peptide Library ◽  
Novel Method ◽  
Phage Peptide Library ◽  
Chymotrypsin Inhibitors ◽  
Selection Of

Selection of Trypsin Inhibitors in Phage Peptide Library

1996 ◽  
Vol 220 (1) ◽  
pp. 53-56 ◽  
Author(s):  
Rui Fang ◽  
Jie Qi ◽  
Zhi-bin Lu ◽  
Hui Zhou ◽  
Wei Li ◽  
...  
Keyword(s):  
Peptide Library ◽  
Trypsin Inhibitors ◽  
Phage Peptide Library ◽  
Selection Of

scholarly journals Selection of Mimotopes of the Cell Surface Adhesion Molecule Mel-CAM from a Random pVIII-28aa Phage Peptide Library

2002 ◽  
Vol 119 (4) ◽  
pp. 865-869 ◽  
Author(s):  
Christine Hafner ◽  
Ursula Samwald ◽  
Stefan Wagner ◽  
Franco Felici ◽  
Elisabeth Heere-Ress ◽  
...  
Keyword(s):  
Cell Surface ◽  
Adhesion Molecule ◽  
Peptide Library ◽  
Surface Adhesion ◽  
Cell Surface Adhesion Molecule ◽  
Phage Peptide Library ◽  
Selection Of

scholarly journals Identification of two linear B-cell epitopes from West Nile virus NS1 by screening a phage-displayed random peptide library

2011 ◽  
Vol 11 (1) ◽  
pp. 160 ◽  
Author(s):  
En-Cheng Sun ◽  
Jian-Nan Ma ◽  
Ni-Hong Liu ◽  
Tao Yang ◽  
Jing Zhao ◽  
...  
Keyword(s):  
West Nile Virus ◽  
B Cell ◽  
Peptide Library ◽  
West Nile ◽  
B Cell Epitopes ◽  
Random Peptide Library ◽  
Random Peptide ◽  
Linear B
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