scholarly journals NADiA ProsVue Prostate-specific Antigen Slope Is an Independent Prognostic Marker for Identifying Men at Reduced Risk of Clinical Recurrence of Prostate Cancer After Radical Prostatectomy

Urology ◽  
2012 ◽  
Vol 80 (6) ◽  
pp. 1319-1327 ◽  
Author(s):  
Judd W. Moul ◽  
Hans Lilja ◽  
O. John Semmes ◽  
Raymond S. Lance ◽  
Robert L. Vessella ◽  
...  
2014 ◽  
Vol 184 (9) ◽  
pp. 2430-2437 ◽  
Author(s):  
Johannes Stein ◽  
Michael Majores ◽  
Magdalena Rohde ◽  
Soyoung Lim ◽  
Simon Schneider ◽  
...  

2006 ◽  
Vol 176 (2) ◽  
pp. 559-563 ◽  
Author(s):  
Shomik Sengupta ◽  
Carl M. Christensen ◽  
Horst Zincke ◽  
Jeffrey M. Slezak ◽  
Bradley C. Leibovich ◽  
...  

2015 ◽  
Vol 33 (1) ◽  
pp. 16.e1-16.e7 ◽  
Author(s):  
Heikki Seikkula ◽  
Kari T. Syvänen ◽  
Samu Kurki ◽  
Tuomas Mirtti ◽  
Pekka Taimen ◽  
...  

1993 ◽  
Vol 149 (4) ◽  
pp. 787-792 ◽  
Author(s):  
Thomas A. Stamey ◽  
Howard C.B. Graves ◽  
Nancy Wehner ◽  
Michelle Ferrari ◽  
Fuad S. Freiha

2020 ◽  
Author(s):  
Yosuke Takakusagi ◽  
Takahiro Oike ◽  
Kio Kano ◽  
Wataru Anno ◽  
Keisuke Tsuchida ◽  
...  

Abstract Background This study aimed to explain the dynamics of prostate-specific antigen (PSA) levels in patients with prostate cancer who were treated with carbon ion radiotherapy (CIRT) and neoadjuvant androgen-deprivation therapy (ADT). Methods Eighty-five patients with intermediate-risk prostate cancer who received CIRT and neoadjuvant ADT from December 2015 to December 2017 were analyzed in the present study. The total dose of CIRT was set at 51.6 Gy (relative biological effectiveness) delivered in 12 fractions over 3 weeks. The PSA bounce was defined as a ≥0.4 ng/ml increase of PSA levels from the nadir, followed by any decrease. PSA failure was defined using the Phoenix criteria.Results The median patient age was 68 (range, 48–81) years. The median follow-up duration was 33 (range, 20–48) months. The clinical T stage was T1c, T2a, and T2b in 26, 44, and 14 patients, respectively. The Gleason score was 6 in 3 patients and 7 in 82 patients. The median pretreatment PSA level was 7.37 (range, 3.33–19.0) ng/ml. All patients received neoadjuvant ADT for a median of 6 (range, 2–116) months. PSA bounces were observed in 39 patients (45.9%), occurring a median of 12 (range, 6–30) months after CIRT. PSA failure was observed in eight patients (9.4%), occurring a median of 21 (range, 15–33) months after CIRT. The 3-year PSA failure-free survival rate was 88.5%. No clinical recurrence was observed during the follow-up period. Younger age was a significant predictor of PSA bounces and PSA failure. Conclusions The dynamics of PSA levels after CIRT was investigated in the present study. Further follow-up is needed to reveal the clinical significance of PSA dynamics.


Urology ◽  
2007 ◽  
Vol 70 (6) ◽  
pp. 1141-1145 ◽  
Author(s):  
Vladimir Mouraviev ◽  
Leon Sun ◽  
John F. Madden ◽  
Janice M. Mayes ◽  
Judd W. Moul ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document