scholarly journals Serum prostate-specific antigen value adjusted for non-cancerous prostate tissue volume in patients undergoing radical prostatectomy: a new predictor of biochemical recurrence in localized or locally advanced prostate cancer

2010 ◽  
Vol 13 (2) ◽  
pp. 248-253 ◽  
Author(s):  
Ja Hyeon Ku ◽  
Kyung Chul Moon ◽  
Sung Yong Cho ◽  
Cheol Kwak ◽  
Hyeon Hoe Kim
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Prostate Specific Antigen ◽  
Biochemical Recurrence ◽  
Advanced Prostate Cancer ◽  
Locally Advanced ◽  
Specific Antigen ◽  
Locally Advanced Prostate Cancer ◽  
Tissue Volume ◽  
Cancerous Prostate Tissue

scholarly journals Treatment of locally advanced prostatic cancer

2010 ◽  
Vol 63 (9-10) ◽  
pp. 689-695 ◽  
Author(s):  
Goran Marusic ◽  
Sasa Vojinov ◽  
Ivan Levakov
Keyword(s):  
Prostate Cancer ◽  
Surgical Treatment ◽  
Radical Prostatectomy ◽  
Lymph Nodes ◽  
Hormonal Therapy ◽  
Advanced Prostate Cancer ◽  
Locally Advanced ◽  
Specific Antigen ◽  
Seminal Vesicles ◽  
Locally Advanced Prostate Cancer

Introduction. A locally advanced prostate cancer is defined as a malignant process spreading beyond the prostate capsule or in seminal vesicles but without distant metastasis or regional lymph nodes invasion. Clinical classification, prediction and treatment of prostate cancer. An exact staging of clinical T3 stadium is usually difficult because of the frequent over and under staging. The risk prognostic stratification is performed through nomograms and ANN (artificial neural networks). The options for treatment are: radical prostatectomy, external radiotherapy and interstitial implantation of radioisotopes, hormonal therapy by androgen blockade. Radical prostatectomy is considered in patients with T3 stage but extensive dissection of lymph nodes, dissection of neurovascular bundle (on tumor side), total removal of seminal vesicle and sometimes resection of bladder neck are obligatory. Postoperative radiotherapy is performed in patients with invasion of seminal vesicles and capsular penetration or with prostate specific antigen value over 0.1 ng/ml, one month after the surgical treatment. Definitive radiotherapy could be used as the best treatment option considering clinical stage, Gleason score, age, starting prostate specific antigen (PSA) value, concomitant diseases, life expectancy, quality of life, through multidisciplinary approach (combined with androgen deprivation). Hormonal therapy in intended for patients who are not eligible for surgical treatment or radiotherapy. Conclusion. Management of locally advanced prostate cancer is still controversial and studies for better diagnosis and new treatment modalities are ongoing.

scholarly journals Complex evaluation of prognostic factors for biochemical recurrence after radical prostatectomy for patients with clinical locally advanced prostate cancer

Health of Man ◽  
2017 ◽  
Vol 0 (1(60)) ◽  
pp. 105-109 ◽  
Author(s):  
В. М. Григоренко ◽  
М. В. Вікарчук ◽  
Р. О. Данилець ◽  
О. О. Банас ◽  
Н. В. Бровко ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Prognostic Factors ◽  
Radical Prostatectomy ◽  
Biochemical Recurrence ◽  
Advanced Prostate Cancer ◽  
Locally Advanced ◽  
Locally Advanced Prostate Cancer ◽  
Complex Evaluation
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