Eotaxin/CCL11 Levels Correlate With Myocardial Fibrosis and Mast Cell Density in Native and Transplanted Rat Hearts

2010 ◽  
Vol 42 (7) ◽  
pp. 2763-2766 ◽  
Author(s):  
M. Zweifel ◽  
K. Matozan ◽  
C. Dahinden ◽  
T. Schaffner ◽  
P. Mohacsi
2007 ◽  
Vol 39 (7) ◽  
pp. 2347-2349 ◽  
Author(s):  
M. Batlle ◽  
F. Pérez-Villa ◽  
A. Lázaro ◽  
E. Garcia-Pras ◽  
J. Ramirez ◽  
...  

2005 ◽  
Vol 99 (1) ◽  
pp. 20-25 ◽  
Author(s):  
John K. Chan ◽  
Alessandra Magistris ◽  
Vera Loizzi ◽  
Fritz Lin ◽  
Joanne Rutgers ◽  
...  

1977 ◽  
Vol 42 (2) ◽  
pp. 174-178 ◽  
Author(s):  
A. Tucker ◽  
I. F. McMurtry ◽  
A. F. Alexander ◽  
J. T. Reeves ◽  
R. F. Grover

Changes in the density and distribution of pulmonary mast cells were determined in six mammalian species exposed to hypobaric hypoxia (PB = 435 Torr) for 19–48 days. Control animals were studied at 1,600 m (PB = 635 Torr). Total lung mast cell hyperplasia was observed only in calves exposed to high altitude. Pigs, rats, and sheep exhibited small, but insignificant, increases in mast cell density. Perivascular mast cell proliferation adjacent to vessels of 30–500 mum in diameter was seen in both calves and pigs. Bronchial, alveolar septal, and systemic tissue (tongue) mast cell hyperplasia was not observed in any of the species. Three indices of pulmonary hypertension (right ventricular hypertrophy, medial thickness of pulmonary arteries, and pulmonary arterial pressure) correlated with perivascular mast cell density. The findings indicate that perivascular mast cell proliferation may relate more to the morphological pulmonary vascular changes and to pulmonary hypertension than to hypoxia, leading to the speculation that mast cells increase in number in response to the hypertension, rather than to mediate and maintain the hypertension.


Author(s):  
Joanne L. Van Der Velden ◽  
Donna Barker ◽  
Garry Barcham ◽  
Emmanuel Koumoundouros ◽  
Stuart Hirst ◽  
...  

2001 ◽  
Vol 30 (6) ◽  
pp. 325-335 ◽  
Author(s):  
Rafael Ramı́rez-Romero ◽  
Kim A. Brogden ◽  
Jack M. Gallup ◽  
Ioana M. Sonea ◽  
Mark R. Ackermann

1999 ◽  
Vol 120 (2) ◽  
pp. 187-197 ◽  
Author(s):  
M.M. Welle ◽  
T. Olivry ◽  
S. Grimm ◽  
M. Suter

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