scholarly journals Mast Cell Density in Oral Submucous Fibrosis : A Possible Role in Pathogenesis

2013 ◽  
Vol 7 (1) ◽  
pp. 23-29 ◽  
Author(s):  
Ravikumar Pujari ◽  
Vidya N.
Keyword(s):  
Mast Cell ◽  
Cell Density ◽  
Oral Submucous Fibrosis ◽  
Mast Cell Density ◽  
Submucous Fibrosis

scholarly journals Immunohistochemical Expression of Mast Cells Using c-Kit in Various Grades of Oral Submucous Fibrosis

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Musarrat J. Khatri ◽  
Rajiv S. Desai ◽  
G. S. Mamatha ◽  
Meena Kulkarni ◽  
Jay Khatri
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Connective Tissue ◽  
Cell Density ◽  
Toluidine Blue ◽  
Oral Submucous Fibrosis ◽  
Blue Staining ◽  
Mast Cell Density ◽  
Submucous Fibrosis ◽  
Pharmacologically Active

Oral submucous fibrosis (OSF) is a high risk precancerous condition characterized by changes in the connective tissue fibers of lamina propria and deeper parts of mucosa. Mast cells are local residents of connective tissue and have been identified to participate in fibrotic process. These cells produce pharmacologically active substances necessary for the physiological function of our body in response to various stimuli as and when required and also play a significant role in the pathogenesis of oral diseases. Ten healthy volunteers and 30 clinically diagnosed OSF cases with histopathological confirmation were included in the study. Immunohistochemical (c-kit) as well as acidified toluidine blue staining techniques were used to evaluate density and expression of mast cells. The mast cell density assessed using c-kit and toluidine blue showed significant difference in various stages of OSF. In general the mean number of mast cells obtained using c-kit was found to be more than that obtained using toluidine blue in various stages of OSF. The comparison of mast cell densities using immunohistochemistry (c-kit) and toluidine blue stain confirmed that c-kit is a more reliable technique to assess mast cell density in OSF.

Mast cell density, angiogenesis, blood clotting, and prognosis in women with advanced ovarian cancer

2005 ◽  
Vol 99 (1) ◽  
pp. 20-25 ◽  
Author(s):  
John K. Chan ◽  
Alessandra Magistris ◽  
Vera Loizzi ◽  
Fritz Lin ◽  
Joanne Rutgers ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Mast Cell ◽  
Cell Density ◽  
Blood Clotting ◽  
Advanced Ovarian Cancer ◽  
Mast Cell Density

Lung mast cell density and distribution in chronically hypoxic animals

1977 ◽  
Vol 42 (2) ◽  
pp. 174-178 ◽  
Author(s):  
A. Tucker ◽  
I. F. McMurtry ◽  
A. F. Alexander ◽  
J. T. Reeves ◽  
R. F. Grover
Keyword(s):  
Cell Proliferation ◽  
Pulmonary Hypertension ◽  
Mast Cell ◽  
Mast Cells ◽  
Cell Density ◽  
Mammalian Species ◽  
Cell Hyperplasia ◽  
Mast Cell Density ◽  
Lung Mast Cell ◽  
Mast Cell Hyperplasia

Changes in the density and distribution of pulmonary mast cells were determined in six mammalian species exposed to hypobaric hypoxia (PB = 435 Torr) for 19–48 days. Control animals were studied at 1,600 m (PB = 635 Torr). Total lung mast cell hyperplasia was observed only in calves exposed to high altitude. Pigs, rats, and sheep exhibited small, but insignificant, increases in mast cell density. Perivascular mast cell proliferation adjacent to vessels of 30–500 mum in diameter was seen in both calves and pigs. Bronchial, alveolar septal, and systemic tissue (tongue) mast cell hyperplasia was not observed in any of the species. Three indices of pulmonary hypertension (right ventricular hypertrophy, medial thickness of pulmonary arteries, and pulmonary arterial pressure) correlated with perivascular mast cell density. The findings indicate that perivascular mast cell proliferation may relate more to the morphological pulmonary vascular changes and to pulmonary hypertension than to hypoxia, leading to the speculation that mast cells increase in number in response to the hypertension, rather than to mediate and maintain the hypertension.

Peripheral Airway Function Is Inversely Correlated With Mast Cell Density In A Sheep Model Of Chronic Asthma

2010 ◽  
Author(s):  
Joanne L. Van Der Velden ◽  
Donna Barker ◽  
Garry Barcham ◽  
Emmanuel Koumoundouros ◽  
Stuart Hirst ◽  
...  
Keyword(s):  
Mast Cell ◽  
Cell Density ◽  
Chronic Asthma ◽  
Sheep Model ◽  
Airway Function ◽  
Mast Cell Density ◽  
Peripheral Airway

scholarly journals Mast cell density and substance P-like immunoreactivity during the initiation and progression of lung lesions in ovineMannheimia (Pasteurella) haemolytica pneumonia

2001 ◽  
Vol 30 (6) ◽  
pp. 325-335 ◽  
Author(s):  
Rafael Ramı́rez-Romero ◽  
Kim A. Brogden ◽  
Jack M. Gallup ◽  
Ioana M. Sonea ◽  
Mark R. Ackermann
Keyword(s):  
Mast Cell ◽  
Substance P ◽  
Cell Density ◽  
Pasteurella Haemolytica ◽  
Lung Lesions ◽  
Mast Cell Density

Mast Cell Density and Subtypes in the Skin of Dogs with Atopic Dermatitis

1999 ◽  
Vol 120 (2) ◽  
pp. 187-197 ◽  
Author(s):  
M.M. Welle ◽  
T. Olivry ◽  
S. Grimm ◽  
M. Suter
Keyword(s):  
Atopic Dermatitis ◽  
Mast Cell ◽  
Cell Density ◽  
Mast Cell Density

Correlation Between Mast Cell Density and Myocardial Fibrosis in Congestive Heart Failure Patients

2007 ◽  
Vol 39 (7) ◽  
pp. 2347-2349 ◽  
Author(s):  
M. Batlle ◽  
F. Pérez-Villa ◽  
A. Lázaro ◽  
E. Garcia-Pras ◽  
J. Ramirez ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Mast Cell ◽  
Cell Density ◽  
Myocardial Fibrosis ◽  
Heart Failure Patients ◽  
Mast Cell Density
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