Optimal Time Duration for Low-Pressure Controlled Reperfusion to Efficiently Protect Ischemic Rat Heart

2007 ◽  
Vol 39 (8) ◽  
pp. 2615-2616 ◽  
Author(s):  
J.C. Bopassa ◽  
C. Nemlin ◽  
L. Sebbag ◽  
C. Rodriguez ◽  
M. Ovize ◽  
...  
2009 ◽  
Vol 41 (2) ◽  
pp. 703-704 ◽  
Author(s):  
C. Nemlin ◽  
S. Benhabbouche ◽  
J.C. Bopassa ◽  
L. Sebbag ◽  
M. Ovize ◽  
...  

Pain Medicine ◽  
2017 ◽  
Vol 19 (1) ◽  
pp. 29-39
Author(s):  
Jan Willem Kallewaard ◽  
José W Geurts ◽  
Michel Terheggen ◽  
Chris Terwiel ◽  
Alfons Kessels ◽  
...  

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
I Arshukova ◽  
T Dugina ◽  
E Dobretsova

Abstract Background Search for possible improvements in outpatient clinic services is a key task for health care professionals worldwide. It is important to consider the satisfaction of the main participants in primary care: patients and doctors. If patients unsatisfied with primary care will not seek help again, this will reduce their life quality and life expectancy. Unsatisfied doctors will work not efficiently nor for a long time. The work is devoted to the search for possible factors, which change may affect the improvement of the situation in clinics in terms of both doctors and patients. Methods The opinions of 1672 patients of Krasnoyarsk outpatient clinics were investigated with the usage of semi-structured interviews. The opinions of 283 physicians of the city were collected using an anonymous questionnaire. Data were analyzed using SPSS 22 by the following methods (p < 0.05): descriptive statistics, U test, χ2-test. Results Coherence of doctors' and patients' opinions investigated in different ways such as primary care satisfaction, desirable main changes, optimal time, duration and structure of appointment, physician's mission, the possibilities of additional medical remote consultations and difficulties in doctors' access. At some points, the answers were consistent; at some, a compromise or new ways of the solutions were required. Conclusions Almost 61% of the doctors prefer morning work time (8-12 am) and 15.5% prefer work in the evenings (18-20 pm) while only 38.1% of patients can visit a doctor in the morning time and 39.5% in the evening. The main changes to be made according to the general opinion of doctors and patients is a reduction of a waiting time of doctors' appointment (38.1% and 38.5% respectively) and the creation of an electronic queue (26.5% and 30.5% respectively). Remote consultation service have to be organized for patients: phone service is more appropriate as for the doctors (30.5%) so as for the patients (34.7%). Key messages The reduction of a waiting time of doctors’ appointment, creations of an electronic queue and a remote consultation service have to be organized to improve primary care system. There is inconsistency in time preferences that have to be solved: doctors prefer to work in morning time and many patients can visit clinics only in the evenings.


2019 ◽  
Author(s):  
Amber M. Johnson ◽  
Marvi Bikak ◽  
Paul M. Griffin ◽  
Mohammad Adibuzzaman

ABSTRACTObjectivesThe aim of this research was to develop data-driven models using electronic health records (EHRs) to conduct clinical studies for predicting clinical outcomes through probabilistic analysis that considers temporal aspects of clinical data. We assess the efficacy of antibiotics treatment and the optimal time of initiation for in-hospitalized diagnosed with acute exacerbation of COPD (AECOPD) as an application to probabilistic modeling.Materials and MethodsWe developed a semi-automatic Markov Chain Monte Carlo (MCMC) modeling and simulation approach that encodes clinical conditions as computable definitions of health states and exact time duration as input for parameter estimations using raw EHR data. We applied the MCMC approach to the MIMIC-III clinical database, where ICD-9 diagnosis codes (491.21, 491.22, and 494.1) were used to identify data for 697 AECOPD patients of which 25.9% were administered antibiotics.ResultsThe average time to antibiotic administration was 27 hours, and 32% of patients were administered vancomycin as the initial antibiotic. The model simulations showed a 50% decrease in mortality rate as the number of patients administered antibiotics increased. There was an estimated 5.5% mortality rate when antibiotics were initially administrated after 48 hours vs 1.8% when antibiotics were initially administrated between 24 and 48 hours.DiscussionOur findings suggest that there may be a mortality benefit in initiation of antibiotics early in patient with severe respiratory failure in settings of COPD exacerbations warranting an ICU admission.ConclusionProbabilistic modeling and simulation methods that considers temporal aspects of raw clinical patient data can be used to adequately generate evidence for clinical guidelines.


Angiology ◽  
1989 ◽  
Vol 40 (6) ◽  
pp. 574-580 ◽  
Author(s):  
Christian Müller ◽  
Wolf Isselhard ◽  
Josef Sturz ◽  
Alfred Wahle ◽  
Henryk Witmanowski ◽  
...  

Author(s):  
Wiwik Handayani ◽  

Project construction activities must be analyzed from the planning stage to the execution stage so that they can be achieved optimally and achieve the best performance point. Project planning relies on a project scheduling system, of course requiring updates and modifications that show the project conditions in real time. The aims of this paper is propose a project scheduling system that can accommodate projects that have large-scale activities by proposing scheduling and risk analysis using Primavera P6 and Primavera risk analysis. A case study was conducted on the construction of an inlet separator fabrication project in Batam, Indonesia. The proposed method aims to calculate the optimal project completion time through automatic scheduling with primavera software. The method demonstrates practical value for project managers in identifying the shortest project duration and estimating the most optimal time duration for carrying out activities. In addition, using automatic scheduling can provide more complex information including successors and predecessors of activities, critical times, estimates of the overall duration of the project.


1992 ◽  
Vol 24 ◽  
pp. 50
Author(s):  
Wolf Isselhard ◽  
Joseph Sturz ◽  
Thorsten Stein ◽  
Thomas Minor ◽  
Stefan Schockhoven ◽  
...  

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