scholarly journals Phosphorylation in Protein-Protein Binding: Effect on Stability and Function

Structure ◽  
2011 ◽  
Vol 19 (12) ◽  
pp. 1807-1815 ◽  
Author(s):  
Hafumi Nishi ◽  
Kosuke Hashimoto ◽  
Anna R. Panchenko
Keyword(s):  
Protein Binding ◽  
Binding Effect ◽  
And Function

Evaluation of Protein Binding Effect on Local Disposition of Oxacillin in Rat Liver by a Two-compartment Dispersion Model

1990 ◽  
Vol 42 (9) ◽  
pp. 632-636 ◽  
Author(s):  
YOSHITAKA YANO ◽  
KIYOSHI YAMAOKA ◽  
TOSHIOMI MINAMIDE ◽  
TERUMICHI NAKAGAWA ◽  
HISASHI TANAKA
Keyword(s):  
Protein Binding ◽  
Rat Liver ◽  
Dispersion Model ◽  
Binding Effect

Synthesis of polyvinylidene fluoride (PVDF) membranes for protein binding: Effect of casting thickness

2012 ◽  
Vol 128 (5) ◽  
pp. 3438-3445 ◽  
Author(s):  
A. L. Ahmad ◽  
N. Ideris ◽  
B. S. Ooi ◽  
S. C. Low ◽  
A. Ismail
Keyword(s):  
Protein Binding ◽  
Polyvinylidene Fluoride ◽  
Binding Effect

Electrostatics in Protein Binding and Function

2002 ◽  
Vol 3 (6) ◽  
pp. 601-614 ◽  
Author(s):  
Neeti Sinha ◽  
Sandra Smith-Gill
Keyword(s):  
Protein Binding ◽  
And Function

scholarly journals Nature and function of insulator protein binding sites in the Drosophila genome

2012 ◽  
Vol 22 (11) ◽  
pp. 2188-2198 ◽  
Author(s):  
Y. B. Schwartz ◽  
D. Linder-Basso ◽  
P. V. Kharchenko ◽  
M. Y. Tolstorukov ◽  
M. Kim ◽  
...  
Keyword(s):  
Protein Binding ◽  
Binding Sites ◽  
Drosophila Genome ◽  
Protein Binding Sites ◽  
Insulator Protein ◽  
And Function

Amitriptyline plasma protein binding: Effect of plasma pH and relevance to clinical overdose

1986 ◽  
Vol 4 (2) ◽  
pp. 121-125 ◽  
Author(s):  
M.Andrew Levitt ◽  
John B. Sullivan ◽  
S.Michael Owens ◽  
Leah Burnham ◽  
Paul R. Finley
Keyword(s):  
Protein Binding ◽  
Plasma Protein Binding ◽  
Plasma Protein ◽  
Binding Effect

scholarly journals Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair

2010 ◽  
Vol 189 (3) ◽  
pp. 445-463 ◽  
Author(s):  
Martijn S. Luijsterburg ◽  
Gesa von Bornstaedt ◽  
Audrey M. Gourdin ◽  
Antonio Z. Politi ◽  
Martijn J. Moné ◽  
...  
Keyword(s):  
Dna Repair ◽  
Protein Binding ◽  
Bound State ◽  
Living Cells ◽  
Dna Lesions ◽  
Trade Off ◽  
Nucleotide Excision ◽  
And Function ◽  
Site Recognition

To understand how multiprotein complexes assemble and function on chromatin, we combined quantitative analysis of the mammalian nucleotide excision DNA repair (NER) machinery in living cells with computational modeling. We found that individual NER components exchange within tens of seconds between the bound state in repair complexes and the diffusive state in the nucleoplasm, whereas their net accumulation at repair sites evolves over several hours. Based on these in vivo data, we developed a predictive kinetic model for the assembly and function of repair complexes. DNA repair is orchestrated by the interplay of reversible protein-binding events and progressive enzymatic modifications of the chromatin substrate. We demonstrate that faithful recognition of DNA lesions is time consuming, whereas subsequently, repair complexes form rapidly through random and reversible assembly of NER proteins. Our kinetic analysis of the NER system reveals a fundamental conflict between specificity and efficiency of chromatin-associated protein machineries and shows how a trade off is negotiated through reversibility of protein binding.

Morphology and polymorph study of a polyvinylidene fluoride (PVDF) membrane for protein binding: Effect of the dissolving temperature

Desalination ◽  
2011 ◽  
Vol 278 (1-3) ◽  
pp. 318-324 ◽  
Author(s):  
A.L. Ahmad ◽  
N. Ideris ◽  
B.S. Ooi ◽  
S.C. Low ◽  
A. Ismail
Keyword(s):  
Protein Binding ◽  
Polyvinylidene Fluoride ◽  
Pvdf Membrane ◽  
Binding Effect
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