scholarly journals A large knee osteochondral lesion treated using a combination of osteochondral autograft transfer and second-generation autologous chondrocyte implantation: A case report

2019 ◽  
Vol 10 ◽  
pp. 10-16 ◽  
Author(s):  
Yuki Kato ◽  
Joverienne Chavez ◽  
Shin Yamada ◽  
Soichi Hattori ◽  
Shuzo Takazawa ◽  
...  
Keyword(s):  
Case Report ◽  
Autologous Chondrocyte Implantation ◽  
Second Generation ◽  
Osteochondral Lesion ◽  
Osteochondral Autograft ◽  
Chondrocyte Implantation ◽  
Osteochondral Autograft Transfer ◽  
Autologous Chondrocyte

Etiology of Cartilage Lesions Does Not Affect Clinical Outcomes of Patellofemoral Autologous Chondrocyte Implantation

Cartilage ◽  
2021 ◽  
pp. 194760352110309
Author(s):  
Alexandre Barbieri Mestriner ◽  
Jakob Ackermann ◽  
Gergo Merkely ◽  
Pedro Henrique Schmidt Alves Ferreira Galvão ◽  
Luiz Felipe Morlin Ambra ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Autologous Chondrocyte Implantation ◽  
Second Generation ◽  
Cartilage Lesion ◽  
Chondrocyte Implantation ◽  
Group 3 ◽  
Group 2 ◽  
Autologous Chondrocyte ◽  
Group 1

Objective To determine the relationship between cartilage lesion etiology and clinical outcomes after second-generation autologous chondrocyte implantation (ACI) in the patellofemoral joint (PFJ) with a minimum of 2 years’ follow-up. Methods A retrospective review of all patients that underwent ACI in the PFJ by a single surgeon was performed. Seventy-two patients with a mean follow-up of 4.2 ± 2.0 years were enrolled in this study and were stratified into 3 groups based on the etiology of PFJ cartilage lesions: patellar dislocation (group 1; n = 23); nontraumatic lesions, including chondromalacia, osteochondritis dissecans, and degenerative defects (group 2; n = 28); and other posttraumatic lesions besides patellar dislocations (group 3; n = 21). Patient’s mean age was 29.6 ± 8.7 years. Patients in group 1 were significantly younger (25.4 ± 7.9 years) than group 2 (31.7 ± 9.6 years; P = 0.025) and group 3 (31.5 ± 6.6 years; P = 0.05). Body mass index averaged 26.2 ± 4.3 kg/m2, with a significant difference between group 1 (24.4 ± 3.2 kg/m2) and group 3 (28.7 ± 4.5 kg/m2; P = 0.005). A clinical comparison was established between groups based on patient-reported outcome measures (PROMs) and failure rates. Results Neither pre- nor postoperative PROMs differed between groups ( P > 0.05). No difference was seen in survivorship between groups (95.7% vs. 82.2% vs. 90.5%, P > 0.05). Conclusion Cartilage lesion etiology did not influence clinical outcome in this retrospective study after second generation ACI in the PFJ. Level of Evidence Level III, retrospective comparative study.

Second-generation arthroscopic autologous chondrocyte implantation for the treatment of degenerative cartilage lesions

2011 ◽  
Vol 20 (9) ◽  
pp. 1704-1713 ◽  
Author(s):  
Giuseppe Filardo ◽  
Elizaveta Kon ◽  
Alessandro Di Martino ◽  
Silvio Patella ◽  
Giulio Altadonna ◽  
...  
Keyword(s):  
Autologous Chondrocyte Implantation ◽  
Second Generation ◽  
Cartilage Lesions ◽  
Chondrocyte Implantation ◽  
Degenerative Cartilage ◽  
Autologous Chondrocyte

Patellofemoral Full-Thickness Chondral Defects Treated With Second-Generation Autologous Chondrocyte Implantation

2009 ◽  
Vol 37 (6) ◽  
pp. 1083-1092 ◽  
Author(s):  
Alberto Gobbi ◽  
Elizaveta Kon ◽  
Massimo Berruto ◽  
Giuseppe Filardo ◽  
Marco Delcogliano ◽  
...  
Keyword(s):  
Autologous Chondrocyte Implantation ◽  
Second Generation ◽  
Full Thickness ◽  
Chondral Defects ◽  
Chondrocyte Implantation ◽  
Autologous Chondrocyte
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